30results about How to "Absorbable" patented technology

The invention discloses a preparation method for a composite hollow material. The preparation method comprises the following steps: growing a metal organic framework thin film by use of a liquid phaseepitaxial growth method, and then performing calcination. The method has the advantages of high synthesis speed, high preparation efficiency, controllable thin film thickness, environmental friendliness, low cost, simplicity for operation and the like, and a convenient method is provided for large-scale preparation. An obtained carbon-based composite material is of a hollow structure and relatively high in electrical conductivity, and has broad application prospect for super capacitors and other electrochemical fields, and electrons can be diffused and transported conveniently.

The invention relates to a preparation method of artificial skin, in particular to a preparation method of artificial skin with hair follicles and the skin made by the method, belonging to biomedical field. The preparation method comprises the following steps: (1) preparing the epithelial cells of the hair follicle; (2) culturing the dermal papilla cells; (3) culturing the artificial skin with hair follicles. The preparation method of artificial skin has the advantages that: (1) the invention originally prepares artificial skin with hair follicles on skin support by hair follicle cells, and reduces the antigenicity greatly compared with the artificial skin made by animal cells; (2) the artificial skin comprises hair follicles, and enable to do physiological functions of skin; (3) the artificial skin is not easy to shrink but easy to absorb; (4) the artificial skin can be used as wound-cover material for large area burn wounded person in clinic and accelerates the wound to heal naturally; (5) the invention resolves the trouble of skin source for large area burn; (6) the preparation method is reasonable in design, convenient in operation and easy in scale production.

The invention relates to an absorbable orthopedic apparatus material having antibiosis and bone growth promotion functions, and a preparation method thereof. The orthopedic apparatus material is obtained by compounding medical pure magnesium or magnesium alloy with an absorbable high-molecular polymer, the surface of the pure magnesium or magnesium alloy has a porous ceramic layer, the surface of the porous ceramic layer is a functional load layer loaded with bone morphogenetic proteins and copper ions with B-type gelatin as a carrier by adopting an electrophoresis-electrodeposition process, the volume fraction of the pure magnesium or magnesium alloy is 1-99%, the micropore aperture and the thickness of the porous ceramic layer on the surface of the pure magnesium or magnesium alloy are 1-100[mu]m and 1-100[mu]m respectively, and the surface of the porous ceramic layer is the functional load layer loaded with bone morphogenetic proteins and copper ions with B-type gelatin as the carrier by adopting the electrophoresis-electrodeposition process. An orthopedic apparatus can slowly release copper ions having a sterilizing effect and bone morphogenetic proteins having a bone growth promotion effect in the use process, can be applied to restore and fix various bone injuries, and has a wide application prospect.

The invention relates to an absorbable magnesium alloy staple having antibiosis and anti-inflammation functions, and a making method thereof. The staple is composed of a pure magnesium or magnesium alloy wire core with the surface containing a porous ceramic layer, an intermediate functional layer loaded with anti-inflammation medicines and copper ions with gelatin as a carrier, and a degradable high-molecular external surface layer. The copper ions and the anti-inflammation medicines are effectively loaded on the surface of the wire with gelatin as the carrier by adopting an electrophoresis-electrodeposition process, and the external surface layer of the staple is a degradable high-molecular layer having a protection effect. The staple can slowly release the copper ions having a sterilizing effect and the anti-inflammation medicines having an anti-inflammation effect in the use process. Additionally, the synergistic effect between the intermediate functional layer with the gelatin as the carrier and the external degradable high-molecular layer realizes the effective control of the medicine release rate and the staple degradation speed. The staple can be widely applied to the stitching or inosculation of the intestine, the stomach and other human body different positions, and has a wide application prospect.

The invention relates to an easy-to-eat food which is characterized by comprising the following components in percentage by weight: 50-60% of water, 8-15% of protein peptide, 20-30% of cereal powder,4-6% of dietary fiber, 1-3% of trehalose, 1-1.5% of DHA algae oil, 0.5-2.5% of thickener, 0-1% of mineral substance, 0-1% of vitamin, 0-0.5% of acidity agent and 0-0.3% of essence. The invention alsoprovides a preparation method of the easy-to-eat food. The easy-to-eat food disclosed by the invention is suitable for the eating requirements of old people with chewing or dysphagia, and the stable property of the product within the shelf life is ensured without water bleeding.

The invention discloses a method for preparing a matrix-induced autologous bone mesenchymal stem cell composite scaffold. The method specifically comprises the steps of preparing bone marrow suspension; taking peripheral blood of a patient and putting the peripheral blood of the patient in a blood bag; preparing autoserum; obtaining target cells; adding 15 ml DMEM high glucose culture medium to the target cells, inoculating a T25 cell culture bottle with the target cells, and placing the T25 cell culture bottle in an incubator for culture; rinsing the cells twice with PBS solution; adding the DMEM high glucose culture medium into the culture bottle dropwise to stop digestion; obtaining cleaned sediment; inoculating the cell culture bottle with the cells for continuous culture; conducting passage three times; adding trypsin-EDTA solution into the culture bottle; washing the cells three times with PBS; conducting cell resuspension; placing a sterile pig source I/III type collagen membrane in a sterile plastic culture dish, and soaking the membrane in the DMEM high glucose culture medium for one night; and dropping cell suspension onto the pig source I/III type collagen membrane, and conducting culture for 3 days. The method has the advantages of being high in treatment precision and the like.

The invention discloses a method for constructing a composite scaffold of pig-derived collagen membrane-autologous chondrocytes. The specific steps are as follows: take the patient's articular cartilage, shake and clean it; cut the cartilage tissue into pieces; obtain cell suspension; precipitate as chondrocytes; Dried the porcine type Ⅰ/Ⅲ collagen membrane, placed it in a sterile plastic plate, slowly dripped the cell suspension on the rough surface of the prepared porcine type Ⅰ/Ⅲ collagen membrane with a plastic sleeve until the collagen membrane reached Wet and saturated state; wait for 10-15 minutes after the collagen membrane adsorbs the cells. The invention has the advantages of good therapeutic effect and the like.

The invention discloses a preparation method and an application of UTY antibody nano-particles for fast separation of X/Y sperms of cattle and sheep. The preparation method comprises steps as follows: a monoclonal antibody resisting a Y sperm UTY antigen is prepared from Y sperm UTY antigen recombinant protein; the monoclonal antibody is subjected to enzyme digestion by pepsase, and Fab' fragments resisting an anti-UTY antigen are obtained through separation; calcium phosphate nano-particles containing the Fab' fragments are prepared. The prepared UTY antibody nano-particles have the capacity of performing antigen-antibody reaction on the surfaces of the Y sperms and inside the Y sperms, thereby leading to Y sperm agglutination, the separation efficiency of X/Y sperms reaches 80%-95%, and the UTY antibody nano-particles have the characteristics of simple, fast and cheap X/Y sperm separation, high efficiency and the like and has extremely small damage.

The invention discloses a medical inflation and curing bone-forming agent for strengthening a vertebral body, which is prepared by mixing the following components in percentage by weight: 10 to 20 percent of expanding agent, 30 to 40 percent of curing agent, 30 to 40 percent of bone-forming agent and the balance of water, wherein the total weight percentage of the expanding agent, the curing agent, the bone-forming agent and the distilled water is 100 percent. The whole strengthening degree of the vertebral body can be obviously enhanced under an osteoporosis condition; the stability of the vertebral body is improved; the leakage of a filled material is reduced; the distribution uniformity of the filled material in the vertebral body is improved; new bones are promoted to be formed in the vertebral body at the same time; an osteoporosis state is improved; and the clinical treatment effect is effectively improved. The medical inflation and curing bone-forming agent is a vertebral body strengthening material, which is obvious in expansion effect and good in mechanical property and bone-forming effect.

The invention discloses a dual-protein sport supplement and a preparation method thereof, and relates to the technical field of sport nutritional foods. The dual-protein sport supplement contains twoproteins consisting of soybean protein and whey protein, as well as nutrient elements such as fat, carbohydrates, vitamins and minerals. The sport supplement of the invention realizes complementary advantages through animal and vegetable proteins, exerts the functions of regulating physiological state, and enables the proteins to enhance the production of muscle protein. The B vitamins in the supplement can promote the burning of fat, and the inositol contained in the supplement can redistribute fat in vivo, has a certain effect on shaping and improving posture, but also can promote the recovery of fatigue after sports. The supplement has the excellent qualities of small particle size, good stability and low energy consumption, is good in taste and low in cost, and accords with the development trend of old and new power conversion of the country. The supplement is reasonable in nutrient collocation and easy to digest and absorb, can meet the nutrient needs of patients with muscle function injury due to age increase and high load sports.

The invention relates to the preparation of a metronidazole dental sustained-release film which is characterized in that the components of the film contain: 10.71% of metronidazole standard, 28.58 % of sodium carboxymethyl cellulose, 42.85% of polyvinyl alcohol-124, and 17.86% of starch. The invention solves the problems of big medicine dosage, poor medical effects and big side effects when oral tablets metronidazole cures parodontopathy, and is widely used by parodontopathy patients.

The invention belongs to the field of fertilizers, and particularly relates to a modified seaweed functional water-soluble fertilizer and a preparation method thereof. The fertilizer comprises the following components: 8-51% of a nitrogen fertilizer, 8-40% of a phosphorus fertilizer, 20-78% of a potassium fertilizer, 0.1-0.2% of a trace element fertilizer, 2-4% of seaweed, 0.1-0.2% of an AT modifier, and 0.1-0.2% of a stabilizer, wherein the AT modifier is prepared by compounding organic acids and alkylphenol ethoxylates. According to the invention, a scheme of mixing alkaline seaweed with macroelements, medium elements and trace elements is adopted, so that the problem of acid-base mixing between seaweed and a macroelement water-soluble fertilizer is solved, organic nutrients and inorganic nutrients are combined, the growth of crops can be activated during fertilization, the growth vigor of the crops is improved, and the quality and yield of the crops are improved; meanwhile, the organic nutrients also have an improvement effect on the soil, and rich absorbable organic nutrients are provided, so that the seaweed and the macroelement, medium element and microelement water-soluble fertilizers have a mutual synergistic effect.

Preparation of a metronidazole slow-release drug membrane for teeth is characterized in that the membrane comprises a metronidazole standard substance, sodium carboxymethylcellulose and polyvinyl alcohol-124. The membrane is made from, according to a ratio, 10.71% of metronidazole, 28.58% of sodium carboxymethylcellulose, 42.85% of polyvinyl alcohol-124, and 17.86% of starch. The problem that an orally-administered metronidazole tablet for treating periodontosis is large in consumption, poor in medical effect and large in side effect is solved. The membrane is widely suitable for patients who suffer from periodontosis.

The invention relates to a novel medical operation glue liquid and a preparation method thereof, and the novel medical operation glue liquid comprises the following components by weight: 100 parts of medical grade injection water, 1-10 parts of sodium carboxymethyl cellulose, 0.3-20 parts of calcium alginate and 2-40 parts of a medical polylactic acid modified polyether type waterborne polyurethane material. The novel medical operation glue liquid is packed by a sterile medical infusion bottle, is simple and easy to use, can be saved in the environment at room temperature for 24 months without losing efficacy, and has good flushing and hemostatic effects on surgical entocoele and acute wounds, the novel medical operation glue liquid is a human body-absorbable material without side effects and bio-risks, and after flushing, the novel medical operation glue liquid can form a tough protective film on the surface of the wounds, and has good anti infection, adhesion-preventing and wound healing accelerating effects.

The invention discloses a preparation method for a collagen membrane inoculated with autologous mesenchymal stem cells. The preparation method comprises the following concrete steps: carrying out uniform mixing so as to obtain a marrow suspension; preparing autologous serum; adding the marrow suspension into a centrifuge tube containing a cell separating medium and carrying out gradient centrifugation to obtain a sediment which is target cells; adding the target cells into 15 ml of a DMEM high-glucose medium containing FGF-2, the autologous serum and gentamycin, carrying out culturing in an incubator and replacing the DMEM high-glucose medium once every three days; after cell culture for 3 to 4 weeks, carrying out passage three times; subjecting cells to resuspension with normal saline; slowly adding the cell suspension onto the rough surface of a prepared pig-sourced I/III type collagen membrane with a plastic sleeve drop by drop; and allowing the collagen membrane to adsorb cells for 10 to 15 min so as to obtain the collagen membrane inoculated with the autologous mesenchymal stem cells. The collagen membrane inoculated with autologous mesenchymal stem cells prepared in the invention has the advantages of good treatment effect, convenience in treatment, low cost, etc.

The invention belongs to the technical field of nutritional foods, and particularly relates to a double-protein nutritional food for the intestinal cancer and a preparation method thereof. The double-protein nutritional food contains protein, fat, carbohydrate, vitamins, minerals, amino acids, ginkgetin and phytosterol nutritional elements. The double-protein nutritional food is suitable for the body characteristics of eaters with the intestinal cancer due to the high-protein, high-carbohydrate and low-fat formula, and is favorable to body rehabilitation; and two proteins are supplemented mutually by the mode of combining soybean protein and ovalbumin, sufficient and comprehensive nutrition is provided to a body, the flavor and state of a product can be improved, and cost of the product can be reduced.

A metronidazole dental slow-release drug film is characterized in that the composition includes: metronidazole standard substance, sodium carboxymethylcellulose, polyvinyl alcohol-124; its ratio is: metronidazole 10.71 1%, carboxy Sodium methylcellulose 28.58%, polyvinyl alcohol-124 42.85%, starch 17.86%. It solves the problems of oral tablet metronidazole in the treatment of periodontal disease, large dose of medicine, poor medical effect, and large side effects, and is widely suitable for the use of periodontal disease patients.

The invention relates to a drug-loaded bone guide/induction composite structure as well as a preparation method and application thereof. The preparation method comprises the following steps: 1) directly or indirectly dissolving an antibacterial drug in a medical adhesive to form a drug-loaded medical adhesive; (2) artificial bone particles with the size of 0.2-1.5 mm are uniformly laid, the thickness is 0.2-1.5 mm, and then the surfaces are coated or sprayed with medicine-carrying medical glue; (3) flatly pressing the collagen membrane to the surface of the medicine-carrying medical adhesive, and gluing the collagen membrane with the artificial bone granular layer to form a composite structure; and 4) after the drug-loaded medical adhesive is dried and solidified, treating the surface of one side of the artificial bone particle with the composite structure, and removing the drug-loaded medical adhesive infiltrated on the surface layer to expose the artificial bone particle, thereby obtaining the drug-loaded bone guiding/inducing composite structure. According to the invention, the convenience of material application, the stability of implantation in vivo and the reliability of guiding/inducing bone regeneration can be improved, and the material is suitable for regeneration of bone defects of different parts/sizes or stable protection of comminuted fracture blocks.

The invention provides a polyester catalyst with antibacterial and osteogenic activity, which is prepared by the following steps: carrying out pre-polycondensation on dicarboxylic acid or dibasic ester and excessive dihydric alcohol to fully react to form a prepolymer; and carrying out transesterification on the prepolymer by using a zinc catalyst, and simultaneously reducing the pressure to continuously remove small molecular byproducts. Compared with the prior art, the invention has the following prominent advantages: (1) the invention provides a novel transesterification catalyst, zinc is an important metal element in a living body, has the characteristics of no toxicity and absorbability, has biological activity and has a promoting effect on proliferation of bone osteoblasts of a human body, and meanwhile, zinc ions have a bactericidal effect, so that the catalyst is a novel transesterification catalyst; and the catalyst is low in cost, can be used massively, and can be applied to the field of biomedicine. And (2) the aliphatic polyester prepared by the invention has the characteristics of degradability and strong safety, and has good market space and value.

The invention provides a probiotic rainbow trout feed and a preparation method thereof. The probiotic rainbow trout feed comprises main materials and auxiliary materials, wherein the main materials comprise fish meal, soybean cake powder, brewer's grains, blood powder and a probiotic leavening agent; and the auxiliary materials comprise bone meal, flour and vegetable oil. After the main materials are fermented through the formula probiotic starter, the probiotics can still keep activity after sterilization and puffing granulation, crude protein and dietary fibers of the main materials are made to have absorbability, and meanwhile, the food calling performance of the feed particles is improved.