85results about How to "Accurate Sensitivity" patented technology

A method for predicting sensitivity to an EGFR inhibitor includes: (a) determining whether there is a KRAS gene-derived nucleic acid or a protein thereof in a blood sample which has been collected from a subject, and whether the KRAS gene-derived nucleic acid or the protein thereof in the blood sample is wild type or mutant; and (b) determining that there is a high possibility that a tumor of the subject is sensitive to an EGFR inhibitor when a wild type KRAS gene-derived nucleic acid or a protein thereof is detected and no mutant KRAS gene-derived nucleic acid or a protein thereof is detected in the blood sample in the process (a).

An azimuth processing device is designed for outputting azimuth data based on measurement data sequentially output from a compass sensor. In the device, an accumulation section selectively accumulates substantially new pieces of the measurement data. An offset data updating section updates offset data of the compass sensor based on plural pieces of the measurement data accumulated by said accumulation section. An azimuth data output section outputs the azimuth data based on substantially newest measurement data and the offset data.

In order to suppress at least one interference signal in an incoming audio signal using a directional microphone system having at least two microphones, that directional microphone signal which has the lowest interference signal component is selected from two or more directional microphone signals that have been produced by weighted combination from the signals of the microphones, with the weighting in each case determining a direction-dependent sensitivity. If a sensitivity distribution has a minimum in the direction of the interference signal source, then a low signal energy is detected, which characterizes a lower interference signal component.

The invention discloses a liquid phase chip for CYP19A1 gene SNP (Single Nucleotide Polymorphism) detection, which comprises wild type and mutant type specific ASPE primers designed targeting CYP19A1 gene SNPs of rs4646, rs10046C>T, rs700519C>T, rs1870050C>A, hCV1664178A>C, rs12900137G>C, rs730154G>A, rs936306T>C and rs1902586A>G, microballoon spheres respectively coated with specific anti-tag sequences and primers used for amplifying CYP19A1 gene SNPs with target sequences to be detected. Each ASPE primer comprises a tag sequence at 5' end and a specific primer sequence at 3' end, wherein the specific primers are selected from SEQ ID NO. 19-36 and the tag sequences are selected from SEQ ID NO.1-18; and the anti-tag sequences can be correspondingly in complementary pairing with the tag sequences. The invention also discloses a CYP19A1 gene SNP detection method. The coincidence rate of the detection method provided by the invention and a sequencing method is as high as 100%; and the prepared liquid phase chip for CYP19A1 gene SNP (Single Nucleotide Polymorphism) detection has excellent signal-to-noise rate, and basically no cross reaction exists between a design probe and the anti-tag sequences.

A magnetic resonance imaging apparatus 20 includes a scan executing unit that executes scan to generate sensitivity map data of an RF coil 24, a region reduction unit 44b that applies region reduction to a signal region near a no-signal region of image data obtained by the scan, a sensitivity map data generating unit 44 that generates sensitivity map data using image data after the region reduction, and a smoothing processing unit 44i that applies three-dimensional smoothing filter to the sensitivity map data.

An implantable cardiac stimulation system capable of automatic capture verification is provided with an associated method for performing automatic testing functions using programmable, or automatically determined, AV delays. Automatic threshold testing and evoked response sensitivity testing performed at a user-specified AV delay setting, rather than a preset setting, allows assessment of automatic capture verification based on an AV delay relevant to daily system function. Further features of the present invention are an adjustable frequency with which automatic threshold tests are performed and an adjustable frequency with which threshold test results are stored in memory in a threshold record for better monitoring of lead stability or impending clinical problems. The frequency of performing threshold tests and the frequency of storing threshold test results may be varied according to the threshold stability. Stored threshold test results are advantageously displayed with respect to a fixed or variable time scale.

An X-ray image diagnostic device of the invention has sensitivity-information-acquisition controlling means commanding synchronization between X-ray irradiation from the X-ray source and readout of X-ray plane detector for correcting sensitivity. When sensitivity information of the X-ray plane detector is calculated using the intensities of X-rays irradiated onto the X-ray plane detector and X-rays detected by the X-ray plane detector, readout of the X-ray plane detector is performed synchronously with X-ray irradiation, and sensitivity information corresponding to variation of the amount of X-ray radiation onto the X-ray plane detector during the reading time is determined using data of every readout channel. Therefore, sensitivity information enabling an accurate sensitivity correction can be obtained from a single output image. This sensitivity information is stored in sensitivity-information-storing means and used for correcting sensitivity of X-ray image data acquired in actual measurements.

A simple and quick protocol for chemical treatment, enzymatic or chemical digestion, and subsequent identification of proteins on protein chip arrays is disclosed, together with kits therefor. The chemical treatment comprises denaturation, reduction and alkylation while enzymatic digestion encompasses deglycosylation, dephosphorylation, and digestion by various proteases. Digestion is also accomplished by various chemicals that are known to induce proteolysis. All reactions are carried out sequentially on chip. Subsequent peptide mass fingerprinting or product ion searches allow the identification of specific peptides which can be correlated to proteins. The method of the present invention can be applied to the analysis of biological samples such as urine and plasma to identify biomarkers in diseased states. The methods of the present invention allow complete on chip treatment, which can be used for rapid protein identification and structural characterization of heavily posttranslationally modified proteins.

A pressure sensor comprising a plurality of sensor parts arranged in matrix. A first electrode being connected with first wiring and a second electrode being connected with second wiring are disposed oppositely through a cavity part in the sensor part. The second electrode bends to the first electrode side in response to a pressure from a specimen and touches the first electrode upon application of a pressure of a specified level or above. When the specimen is pressed against a pressure detecting region, both electrodes touch each other at a sensor part corresponding to a protrusions of the specimen and are separated at a sensor part corresponding to a recess. When a scanning signal is fed from a scanning circuit to one wiring and presence of a signal flowing through the second wiring is detected by a sensing circuit, a pressure being applied to each sensor part can be detected. Furthermore, the shape is detected by feeding the scanning signal from the scanning circuit to each first wiring sequentially and scanning the pressure detecting region generally.

A touch type input terminal that includes a base substrate, a piezoelectric sensor and an electrostatic sensor which are flat membrane-shaped, respectively. The electrostatic sensor includes a plurality of segment electrodes on a first main surface of a base film and a plurality of common electrodes on a second main surface. The piezoelectric sensor includes a piezoelectric film formed of PLLA drawn uniaxially. Displacement detecting electrodes are formed on a third main surface of the piezoelectric film so as to divide the third main surface into four portions. Displacement detecting electrodes are formed on a fourth main surface of the piezoelectric film so as to be opposed to the displacement detecting electrodes on the third main surface.

The invention provides a method and system for detecting and verifying partial discharge of a power transformer through ultrasonic sensors. The method for detecting and verifying the partial discharge of the power transformer through the ultrasonic sensors includes the steps that A longitudinal wave detection is carried out on the ultrasonic sensors, B the ultrasonic sensors carry out partial discharge detection on the power transformer, and C the ultrasonic sensors carry out positioning detection on the partial discharge. The system for detecting and verifying the partial discharge of the power transformer through the ultrasonic sensors includes an ultrasonic sensor longitudinal wave detection system, an ultrasonic sensor power transformer partial discharge detection system and an ultrasonic sensor power transformer partial discharge positioning detection system. Compared with the prior art, the method and system for detecting and verifying the partial discharge of the power transformer through the ultrasonic sensors achieves the performance evaluation of the power transformer partial discharge and positioning detection accurately, simply and conveniently through the different sensors.

A method of generating an MR image based on respective data obtained by n (≧2) coils, respective low resolution images are generated using partial data in a low frequency region for the data obtained by the n coils. The intensities and phases of the low resolution images are corrected. The post-correction images are added together to generate one composite low resolution image. Sensitivity maps of the respective coils are created from the composite low resolution image and the respective low resolution images. One image is generated from the respective data and the respective sensitivity maps.

The invention relates to a zoom lens system which is compatible with a TTL optical finder having a diagonal field angle of at least 70° at the wide-angle end and about 7 to 10 magnifications and is fast as represented by an F-number of about 2.8 at the wide-angle end. The zoom lens system comprises a first lens group G1 which is movable along its optical axis during zooming and has positive refracting power, a second lens group G2 which moves toward the image side along the optical axis during zooming from the wide-angle end to the telephoto end and has negative refracting power and rear lens groups G3 to G6 having at least two spacings variable during zooming. In particular, the focal length f1 of the first lens group G1 should meet 6<F1 / L<20 where L is the diagonal length of an effective image pickup surface I located in the vicinity of an image-formation plane.

A method for fabricating an active device array substrate is provided. A first patterned semiconductor layer, a gate insulator, a first patterned conductive layer and a first dielectric layer is sequentially formed on a substrate. First contact holes exposing the first patterned semiconductor layer are formed in the first dielectric layer and the gate insulator. A second patterned conductive layer and a second patterned semiconductor layer disposed thereon are simultaneously formed on the first dielectric layer. The second conductive layer includes contact conductors and a bottom electrode. The second patterned semiconductor layer includes an active layer. A second dielectric layer having second contact holes is formed on the first dielectric layer, wherein a portion of the second contact holes exposes the active layer. A third patterned conductive layer electrically connected to the active layer through a portion of the second contact holes is formed on the second dielectric layer.

The invention discloses a sub-THz nano-biosensor for quickly frame-detecting bacteria and a detection method thereof, and belongs to the technical field of sensors. The sensor includes a microfluid unit and a sample detection pool consisting of slot nanotube antennas, wherein the microfluid unit includes at least one microfluid body which is with a tubular structure, a positive pressure generating device arranged at the cell inlet end of the microfluid body, and a negative pressure generating device arranged at the cell outlet end of the microfluid body. The invention also discloses a detection method of the sensor, wherein bacterium sample liquid is fully diluted and passes through the microfluid sample detection pool to be subjected to THz spectrum detection. According to the sub-THz nano-biosensor for quickly frame-detecting bacteria and the detection method thereof, enough negative pressure is generated in the microfluid, so that cells to be detected only can pass through the microfluid body with small diameter singly or in small number, so that detection specificity is effectively improved; in addition, the signal of single cell is amplified by the slot nanotube antennas, so that the sensitivity problem of single cell detection is thoroughly solved, and thereby the bacterium cells with different characters can be distinguished and recognized.

The invention relates to the filed of car crash experimental devices, particularly to a device and method for calibrating sensitivity of chest displacement sensors in a dummy in a car crash test. The device includes a plurality of mutually independent measuring blocks suitable for being mounted at the chest of the dummy, to push the chest displacement sensors at the original positions in the chest of the dummy to move; and the measuring blocks are different in length, so as to prompt the chest displacement sensors to generate corresponding displacement. As the calibrating device is provided with the plurality of mutually independent measuring blocks suitable for being mounted at the chest of the dummy respectively and being different in length, the chest displacement sensors can be calibrated through adopting the measuring blocks to push the chest displacement sensors at the original positions in the chest of the dummy to move, as a result, the influence on the sensitivity of the chest displacement sensors, caused by dismounting and mounting of the chest displacement sensors in the prior art can be reduced.

The invention, which belongs to the technical field of tobacco component detection, relates to an analytical method for quantitatively measuring super-multi-target aroma components in tobacco. The method comprises the following steps that: a tobacco sample is immersed in an acidic buffer solution and extraction is performed by an organic solvent; a multi-walled carbon nanotube is used as a reversesolid phase-dispersed adsorbent and vortexing and centrifugation are performed to purify the sample; and then simultaneous detection of 345 kinds of aroma component in tobacco is realized by combining gas chromatography-tandem mass spectrometry. The method has advantages of simple and rapid operation, high flux, low cost, low solvent dosage, good environmental friendly effect, wide range of analytical compounds, high accuracy, high precision, high sensitivity and high repeatability and can satisfy the demand of rapid detection and analysis of aroma component in tobacco.

An image signal output device for use in a passive range finder. The device can correct the sensitivities of sensor arrays according to the amount of incident light. The output device has line sensor portions that produce pixel outputs. An A / D converter portion A / D converts these pixel outputs. At this time, the A / D conversion range of the A / D converter portion is modified according to the difference in sensitivity between the line sensor portions.

Voltage signals outputted from a CCD are subjected to correlated double sampling processing by a correlated double sampling circuit (CDS), after which digital gain processing is carried out at a gain control amplifier (GCA). A gain difference between G color signals and R / B color signals outputted from the CCD is caused by a difference between a G exposure duration tG and an R / B exposure duration tR / B. When the value of a ratio between the tG and the tR / B falls below a predetermined value, the GCA applies digital gain for compensating for the gain difference by multiplying respective signal values of R, G and B by gain correction coefficients as follows: (gain compensation coefficient α)=(G exposure duration tG) / (R / B exposure duration tR / B)=(G exposure duration tG) / ((G exposure duration tG)+(exposure duration difference Δt)).

The present invention provides methods for culturing primary cells and tissues from a subject in the presence of the subject's own serum, ascites or pleural effusion fluid. Methods of treating cancer, and screening for the effectiveness or toxicity of drugs are also provided herein.

The invention discloses a reactive compensation method applicable to areas accessed by wind power plant groups, and belongs to the technical field of power system analysis, operation and control. On the basis of the current condition that wind power plants massively and intensely access to power grids, supporting effect of reactive adjustment amount and far-field reactive compensation to voltages of observation points is determined through equivalent sensitivity of active increment, and a reactive compensation scheme is analyzed according to the supporting effect. The reactive compensation method includes the steps of forming of a modified wind-power-plant voltage correction equation, determination of reactive compensation points and determination of reactive compensation capacity. By the reactive compensation method, influences of volatility and randomness of wind power on determination of voltage adjustment amount are removed, calculation accuracy is improved, compensated candidate node number is increased, and system reactive adjustment is more flexible.

The present invention is directed to an image-forming optical system. The image-forming optical system according to the present invention contains, in order from an object side: an iris diaphragm; a first lens having a positive refractive power and at least one aspheric surface; and a second lens having a negative refractive power and at least one aspheric surface. In accordance with the present invention, there is provided an image-forming optical system for cameras using an image pickup device that has a small number of lenses to easily realize the compactness and satisfies a requirement for a high optical performance.

The invention discloses a method for testing the cost of an optical channel, which is suitable for a product calibrated by a receiver. Compared with a method for testing the cost of the optical channel by measuring sensitivity twice on the basis of an optical attenuator, the method for testing the cost of the optical channel solves the problems of plugging consistency of optical fibers, calibration of the variable optical attenuator and the like. Compared with a method for testing the cost of the optical channel by utilizing an optical switch, the method for testing the cost of the optical channel does not need to use an optical splitter or the optical switch. The method can reduce the cost of a test system and can also improve the accuracy of testing the cost of the optical channel.

Provided is a potentiostatic electrolytic gas sensor that can perform gas detect with high reliability. In the potentiostatic electrolytic gas sensor, a working electrode and a counter electrode are provided inside a casing with an electrolytic solution interposed therebetween. A working electrode lead member is drawn out of the casing at one end, and electrically connected to the working electrode at the other end. A counter electrode lead member is drawn out of the casing at one end and electrically connected to the counter electrode at the other end. The potentiostatic electrolytic gas sensor is characterized in that at least one of the working electrode lead member and the counter electrode lead member is made of a metal selected from gold, tungsten, niobium, and tantalum.

The invention relates to a fiber grating two-dimensional vibration sensor with an adjustable measuring range. The fiber grating two-dimensional vibration sensor comprises a cylindrical and hollow base, the inner surface of the base is provided with a convex ring, a coaxial threaded round rod is fixed to the inner bottom surface of the base, the middle of the threaded round rod is sleeved by a pair of mass rings through screw-thread fit, a coaxial fiber fixing plate is fixed at the top end of the threaded round rod, a fiber grating is fixed on the fiber fixing plate and the convex ring, a first grating to a fourth grating are arranged on the fiber grating successively and are all located in the annulus space between the fiber fixing plate and the convex ring. When a certain point on the axis of the threaded round rod is used as an origin, a plane passing through the origin and perpendicular to the axis is defined as a coordinate plane. The first grating and the second grating are located in the X-axis direction, the third grating and the fourth grating are located in the Y-axis direction, and the pre-tightening forces of the first grating to the fourth grating are equal. The sensor uses a fiber grating as a sensing element, is high in measurement accuracy, can flexibly change sensitivity to adjust a measuring range, and eliminates the influence of the accidental factors.

The invention belongs to the field of traditional Chinese medicines, and the invention discloses a content determination method of a traditional Chinese medicine composition. The method comprises (a) the preparation of a sample solution, (b) the preparation of a reference solution, (c) chromatographic conditions, to be more specific, a chromatographic column of C18 reversed phase chromatographic column, the column temperature of 30 DEG C, mobile phases of A acetonitrile and B trifluoroacetic acid solution, the gradient elution flow rate of 0.4ml / min, detection wavelengths of 230nm and 327nm, and (d) determination. The method is strong in specificity and simple in operation, and the quality of the traditional Chinese medicine composition can be effectively controlled.

The invention discloses a method for zeroing the initial null voltage of a bridge sensor. The method comprises a step 1 of accurately measuring the Wheatstone bridge initial null voltage, the input resistance and the output resistance of the bridge sensor before the bridge sensor is fabricated and packaged; a step 2 of calculating the average resistance of the bridge sensor; a step 3 of calculating zeroing resistance connected in parallel with an arm with higher potential; a step 4 of forming a zeroing resistor with the required resistance by means of series connection or parallel connection from a zeroing resistor sequence; a step 5 of connecting the zeroing resistor in parallel to the arm with the higher potential, and completing the package test of the bridge sensor. In the invention, an external zeroing method of the sensor is transformed into an internal zeroing method, and a zeroing test and production are carried out by a sensor manufacturer. When using the bridge sensor, the user does not need to zero the bridge sensor anymore. A high receiving degree is achieved. Compared with the zeroing of an external parallel potentiometer, the method is stable and reliable in connection and prolongs a service life.

The invention discloses a liquid phase chip for CYP19A1 gene SNP (Single Nucleotide Polymorphism) detection, which comprises wild type and mutant type specific ASPE primers designed targeting CYP19A1 gene SNPs of rs4646, rs10046C>T, rs700519C>T, rs1870050C>A, hCV1664178A>C, rs12900137G>C, rs730154G>A, rs936306T>C and rs1902586A>G, microballoon spheres respectively coated with specific anti-tag sequences and primers used for amplifying CYP19A1 gene SNPs with target sequences to be detected. Each ASPE primer comprises a tag sequence at 5' end and a specific primer sequence at 3' end, wherein the specific primers are selected from SEQ ID NO. 19-36 and the tag sequences are selected from SEQ ID NO.1-18; and the anti-tag sequences can be correspondingly in complementary pairing with the tag sequences. The invention also discloses a CYP19A1 gene SNP detection method. The coincidence rate of the detection method provided by the invention and a sequencing method is as high as 100%; and the prepared liquid phase chip for CYP19A1 gene SNP (Single Nucleotide Polymorphism) detection has excellent signal-to-noise rate, and basically no cross reaction exists between a design probe and the anti-tag sequences.