The invention provides an industrial sewing machine operating panel with the voice prompt function. The industrial sewing machine operating panel comprises an MCU, an indicating unit, a display unit, an electric control connecting interface, a voice processing module and a loudspeaker, wherein the indicating unit, the display unit, the electric control connecting interface, the voice processing module and the loudspeaker are connected with the MCU, the electric control connecting interface is an interface connected with a motor controller of a control system, and the MCU is further provided with a keyboard interface for being connected with a keyboard. The industrial sewing machine operating panel with the voice prompt function can timely give out an alarm when an operator presses wrong keys, and therefore the phenomenon that a fault occurs to the industrial sewing machine because of error operation on the keyboard can be avoided; besides, when the fault occurs, received fault codes can be read by the MCU to find the corresponding fault and the corresponding solution through the voice processing module, and the fault and the solution are broadcast through the loudspeaker, and therefore a maintenance person only needs to maintain the fault according to the broadcast content, and maintenance difficulty of the industrial sewing machine is greatly reduced.