46 results about "Cell cavity" patented technology

The invention relates to a multi-pass cell cavity structure capable of realizing single-concentration standard gas rapid double-point calibration, which is characterized by comprising a laser device, a cavity mirror I with an entrance port, a cavity mirror II with an entrance port, a reflecting mirror and a detector, and the laser device, the reflecting mirror and the detector are positioned on the outer side of the cavity mirror I; the first cavity mirror and the second cavity mirror are oppositely arranged, a double-face cavity mirror is arranged between the first cavity mirror and the second cavity mirror, emitted light of the laser enters the light cavity between the first cavity mirror and the second cavity mirror from the incidence port according to the incidence angle designed by the multi-pass cell, goes back and forth in the light cavity for multiple times and then is emitted out from the incidence port, and emitted emergent light enters the detector through the reflecting mirror. The detector is used for measuring laser intensity changes. The multi-pass cell cavity is ingenious in structure, double-point calibration based on single-concentration standard gas can be achieved through the additionally-arranged double-face cavity mirror, the calibration frequency can be reduced, the calibration rate can be increased, then the standard gas for calibration can be saved subsequently, the use cost can be reduced, and the use experience can be enhanced.

The invention relates to the technical field of tissue engineering, in particular to a 3D printing platform integrated with holographic optical tweezers and a bionic tissue construction method.The printing platform comprises a holographic optical tweezers module used for forming an optical trap array in an objective lens focal region of the holographic optical tweezers module; the charging barrel is used for storing biological materials and can move between a storage position and a working position; the printing base can move between the feeding station and the optical tweezer control station; the objective table is installed on the printing base and can move in the horizontal direction and the vertical direction; the light curing device is fixed on the objective table and is used for emitting light to induce the biological material to be cured; the cell culture plate is fixed on the objective table and stacked on the photocuring device; the cell culture plate is provided with a printing chamber and a cell chamber, and the printing chamber and the cell chamber are communicated through a channel. A macroscopic ordered three-dimensional structure can be constructed, and ordering and patterning of microscale organisms in the macroscopic three-dimensional structure are also realized.

An ultra-high flux quantitative phase imaging (QPI) system incorporates a real-time rotating cell detection based platform with concentric annular cell chambers (20). Each chamber (20) has a detection region (22) and a pair of access channels (24) with openings (25) between the ends. The access channel (24) serves to deliver a fluid containing the cell sample introduced into the opening (25) to the detection region (22). The opening (25) faces an inner radial position of the rotating platform compared to the detection area (22) so as to prevent liquid within the detection area (22) from being squeezed out by centrifugal force when the platform rotates, while communicating with the external environment before, during and after rotation.

The present application relates to the technical field of quantum sensing based on atomic cell, in particular to a light glue inner mirror surface reflection multi-optical path atomic cell and application thereof. The light glue inner mirror surface reflection multi-optical path atomic cell of the present application increases the optical path of the probe laser in the atomic cell cavity and amplifies the signal without changing the size of the spectral analysis cell chamber; ultimately, the fundamental sensitivity of the measurement is limited by the quantum shot noise of the atoms, and the limit of such sensitivity is called the standard quantum limit, which is inversely proportional to the square root of the number of atoms simultaneously detected in the chamber. The multi-optical path design of the light glue inner mirror surface reflection multi-optical path atomic cell of the present application can make the probe laser cover the entire cross section of the atomic cell cavity and simultaneously detect almost all the atoms in the atomic cell cavity, thereby greatly improving the signal-to-noise ratio of the measurement and the sensitivity under the standard quantum limit caused by the shot noise.

The utility model provides a superconducting electron linear accelerator device for isotope production, which comprises an injector, a superconducting acceleration module and an irradiation target area which are arranged in sequence, and the superconducting acceleration module is connected with a low-temperature cooling system, a radio frequency driving system and a control system; the superconducting acceleration module comprises a low-beta-value Ni3Sn superconducting cavity and five standard Ni3Sn superconducting cavity modules, the low-beta-value superconducting cavity is an SRF acceleration cavity of a 2-cell cavity with beta = 0.7, and each standard superconducting cavity module consists of four SRF acceleration cavities of the 2-cell cavity with beta = 1 which are connected in series; and the input end of the standard superconducting cavity module adopts a symmetrical double-input coupler. According to the linear accelerator device provided by the utility model, the Ni3Sn superconducting cavity adopts a 2-cell and double-input coupler structure, so that the power requirement of high-power input coupling can be reduced under high flow intensity, a high-power electron beam is generated at lower cost, and efficient and economic production of isotopes is realized.

The invention relates to a chip for cell sorting by laser-induced forward transfer, relates to the technical field of cell sorting, and solves the technical problems that in the cell sorting process in the prior art, micro-explosion can strongly impact and damage cells and interfere with research and analysis on cells obtained through sorting. The chip comprises a substrate, a sacrificial layer, an explosion cavity membrane, an isolation layer membrane and a cell cavity membrane which are sequentially arranged from bottom to top. When the chip for cell sorting through laser-induced forward transfer is used for LIFT target cell sorting, impact damage to target cells in the LIFT process can be effectively buffered and reduced, and the activity of the target cells obtained through sorting is improved.

A magnetorheological apparatus includes a flexible body formed of an elastomer material, a plurality of cell cavities defined by the flexible body, a magnetorheological (MR) fluid disposed within each cell cavity of the plurality of cell cavities, and a magnetic field inductor positioned adjacent to at least one of the cell cavities. Each cell cavity of the plurality of cell cavities is fluidly encapsulated within the flexible body. The magnetic field inductor is selectively operable to vary a magnetic field, and the MR fluid within the at least one cell cavity is configured to vary a stiffness of the at least one cell cavity in response to the magnetic field.

The present application discloses an electrocatalytic in-situ Mössbauer spectroscopy sample cell and its application; the electrocatalytic in-situ Mössbauer spectroscopy sample cell includes a proton exchange membrane, a working electrode cell cavity, and a counter electrode cell cavity; the working electrode cell cavity is horizontally fixedly connected to the counter electrode cell cavity; a through hole is provided on the cavity wall connecting the working electrode cell cavity and the counter electrode cell cavity; a concave groove is provided at the through hole, and the proton exchange membrane is located in the concave groove. The working electrode is perpendicular to the radiation source. Due to the different positions of the radiation source, two sample cells with different orientations are designed. The electrolytic cell can avoid the interference caused by the oxygen evolution reaction of the counter electrode and can better obtain the real reaction state of the catalyst; it is suitable for Mössbauer spectroscopy devices of different elements (Fe / Sn); it can also be applied to different electrocatalytic reactions (CO2 / N2 reduction reaction).

The application discloses a kind of frame of battery pack, battery pack and vehicle, it is related to new energy technology field.Frame includes: edge beam, elastomer and drive adjustment structure.Edge beam is connected in sequence multiple roots, and multiple edge beams are enclosed to form cell cavity, and at least one edge beam is provided with accommodating groove on the side towards cell cavity;Elastomer is arranged in accommodating groove, one end of elastomer is connected with edge beam, and the other end is used to extrude cell to adjust the expansion force of cell;Drive adjustment structure is connected with elastomer to adjust the expansion amount of elastomer.According to the frame of battery pack of the embodiment of the application, the constraint force of cell can be dynamically adjusted, the use reliability of cell is ensured, and then the use performance of battery pack is optimized.

The present invention relates to the technical field of tissue engineering, and in particular to a 3D printing platform integrated with holographic optical tweezers, and a bionic tissue construction method. The printing platform comprises: a holographic optical tweezer module configured to form an optical trap array in a focal region of an objective lens of the holographic optical tweezer module; material barrels configured to store biological materials and capable of moving between a storage position and a working position; a printing base capable of moving between a material loading station and an optical tweezer manipulation station; an object stage mounted on the printing base and capable of moving in horizontal and vertical directions; a photocuring device fixed on the object stage and configured to emit light to induce the biological materials to be cured; and a cell culture plate fixed on the object stage and stacked on the photocuring device, wherein the cell culture plate has a printing chamber and a cell chamber, and the printing chamber and the cell chamber are in communication with each other by means of a channel. A macroscopic ordered three-dimensional structure can be constructed, and micro-scale organisms inside the macroscopic three-dimensional structure are also ordered and patterned.

The utility model provides a kind of battery pack and electric equipment, battery pack includes first cabinet and second cabinet, first cabinet forms the cell cavity with one side opening, and second cabinet cover is located in opening;Support is located in cell cavity, and is supported between first cabinet and second cabinet, support is provided with hollow structure along its length direction and is penetrated.This application technical scheme is by being provided with hollow structure in support, so, when support is deformed inward by external pressure or impact force, hollow structure in support can be deformed in support Space is left for bracket, to relieve stress concentration caused by external impact, reduce the stress damage probability of support, prolong the service life of support.

The utility model belongs to the technical field of flow cells, and particularly relates to a low-optical-path flow cell which comprises a cell cover and a cell cover, the cell cover is fixedly connected to one end of the cell cover, a cell inlet pipe and a cell outlet pipe which are symmetrically distributed are arranged in the middle of the cell cover, a cell cavity is formed in the middle of the cell cover, stepped grooves are formed in the two sides of the cell cover, and the stepped grooves are communicated with the cell cover. A stepped groove is formed in one side of the pool cover, one end of the stepped groove communicates with the pool cavity, a pool window assembly is in threaded connection with the interior of the stepped groove, a lens is connected to the middle of the pool window assembly in a clamped mode and detachably installed in the stepped groove through the pool window assembly, and a square groove is fixedly connected to one side of the pool cover; one end of the pool inlet pipe and one end of the pool outlet pipe are embedded in the square groove. According to the utility model, the lens is installed inside the pool cavity through the pool window assembly, during installation, the lens is clamped on the pool window assembly firstly and then is installed inside the pool cavity, and during disassembly and assembly, the pool window assembly and the lens are of an integrated structure, so that disassembly and assembly are convenient, and the disassembly and assembly efficiency is improved.

The application relates to a carbonate carbon and oxygen isotope analysis device which comprises a rotating table and a measuring mechanism, a plurality of ablation cell cavities are arranged on the rotating table along the circumference of the rotating table, the ablation cell cavities are provided with gas inlets and outlets; components of the measuring mechanism are sequentially arranged along the ablation cell cavities, and the measuring mechanism comprises a laser system, an exhaust unit, a purification sampling unit and a gas isotope mass spectrometer; the laser system is located above the ablation cell cavities and is provided with a laser action area, the laser action area is located on the movement path of the ablation cell cavities; the exhaust unit is used for being connected with the gas inlets and outlets to replace air in the ablation cell cavities with helium; the purification sampling unit is used for being connected with the gas inlets and outlets to sample; and the gas isotope mass spectrometer is connected with the purification sampling unit. The ablation cell cavities are arranged on the rotating table, and the measuring mechanism is matched, so that different samples can be independently and continuously subjected to exhaust, ablation reaction and purification test, and the test efficiency can be improved.

The present invention discloses a compact and efficient pump-probe optical system, which relates to the field of pump-probe technology. The optical path structure includes a first reflector, a second reflector, an ultraviolet reflector, and a multi-pass cell cavity. The first reflector and the second reflector are respectively provided with a first circular hole and a second circular hole at their centers. The ultraviolet reflector is mounted at the first circular hole in the center of the first reflector, and its working surface is convex and faces the second reflector. The incident beam of the photolysis laser enters through the second circular hole and is incident on the ultraviolet reflector along the optical axis of the multi-pass cell. It is then diverged and reflected by the ultraviolet reflector to the second reflector. It is reflected and collimated by the second reflector into a collimated beam, which covers the probe laser reflected back and forth in the multi-pass cell. The present invention has high mirror surface utilization, dense reflected light spots, and the photolysis beam completely covers the probe beam. It can obtain an effective overlapping optical path of up to 100 meters with a short base length, achieving a small size and high sensitivity.

The invention provides a non-structural PHT spline storage and calculation method and system, and belongs to the field of computer-aided geometric design, and the method comprises the steps: S1, inputting a complex curved surface # imgabs0 # which needs to be fitted; a proper parameterization method is selected, and the # imgabs1 # is mapped to a cube parameter domain or a rectangular parameter domain; s2, generating an initial grid # imgabs2 on the basis of the half-edge data structure and the parameter domain; s3, geometric information of # imgabs3 # at a # imgabs4 # base point of the initial grid is calculated, and a Bezier longitudinal mark of a # imgabs5 # cell cavity is updated by using an interpolation theorem; s4, comprehensively considering the fitting precision and the number of grid layers, subdividing the cells which do not meet the requirements in the current layer layer by layer, updating the Bezier longitudinal standard, and finally obtaining an optimized grid # imgabs6 #; and S5, outputting the PHT spline corresponding to the # imgabs7 # as an STEP format. According to the method, the algorithm process of fitting the open curved surface and the closed curved surface through the PHT spline is unified, the continuity of the spline curved surface is guaranteed, and a solution is provided for downstream tasks of complex curved surface modeling.

The present application relates to the technical field of quantum sensing based on atomic cell, in particular to a light cement total reflection multi-optical path atomic cell and its application. The light cement total reflection multi-optical path atomic cell comprises an atomic cell cavity, a window sheet and a right-angle prism; two side opening positions of the atomic cell cavity are provided with the window sheet, the window sheet is connected with the atomic cell cavity by light cement, and the side of the window sheet away from the atomic cell cavity is provided with the right-angle prism allowing multiple reflections of the probe laser; the window sheet is provided with an entrance and an exit allowing the probe laser to enter and exit. In use, the probe laser beam is totally reflected back and forth between the two right-angle prisms and passes through the atomic cell cavity multiple times; the atomic cell cavity allows the light intensity of the probe laser to be uniformly distributed in the atomic cell cavity, so that almost all the atoms in the atomic cell cavity can be detected at the same time, thereby improving the detection signal intensity and the sensitivity under the standard quantum limit determined by the atomic shot noise.

The invention discloses a cold connection integrated liquid cooling battery box, which comprises a box frame and a liquid cooling assembly, the liquid cooling assembly is installed in the box frame, the box frame is enclosed by a front beam, a rear beam and two side beams, the liquid cooling assembly comprises an upper layer liquid cooling plate, a middle layer liquid cooling plate and a lower layer liquid cooling plate, the upper layer liquid cooling plate is installed at the top of the box frame, and the middle layer liquid cooling plate is installed at the bottom of the box frame. The lower-layer liquid cooling plate is mounted at the bottom of the box body frame, the middle-layer liquid cooling plate is mounted in the box body frame, an upper-layer battery cell cavity is formed between the middle-layer liquid cooling plate and the upper-layer liquid cooling plate, and the middle-layer liquid cooling plate and the upper-layer liquid cooling plate can be used for cooling the upper surface and the lower surface of a battery cell in the upper-layer battery cell cavity respectively; a lower-layer battery cell cavity is formed between the middle-layer liquid cooling plate and the lower-layer liquid cooling plate, the middle-layer liquid cooling plate and the lower-layer liquid cooling plate can perform heat dissipation on the upper surface and the lower surface of a battery cell in the lower-layer battery cell cavity respectively, and synchronous heat dissipation of the upper surface and the lower surface of the battery cell is achieved through the embedded design of the three layers of liquid cooling plates; and stable cold connection installation of the liquid cooling plate is realized through combination of glue joint and threaded connection.

This invention belongs to the field of computer image processing and computational wood science, specifically relating to an intelligent batch identification and analysis system for cells in cross-sections of gymnosperm wood. The system includes sequentially connected modules for image input, preprocessing, cell instance segmentation, unique ID generation and management, batch calculation of geometric parameters, and result output and interactive filtering. The method involves: after preprocessing the input image, using instance segmentation based on traditional image processing algorithms to batch identify cell outlines; assigning a unique ID to each cell and establishing a mapping; calculating the cell lumen area, diameter, and wall thickness in batches based on the mapping relationship; and finally, performing visualization and interactive filtering. This invention, by integrating batch parallel processing and cell instance-ID mapping management, achieves minute-level fully automated identification and measurement of massive numbers of cells in wood cross-sections, improving efficiency by hundreds of times compared to manual serial operations, and supports fine-grained data management and statistics.

The invention relates to the technical field of decellularization systems, and discloses an animal material decellularization system and a use method.The animal material decellularization system comprises a tank body, a liquid inlet pipe is installed at the top of the tank body, and a liquid outlet pipe is installed at the bottom of the tank body of a decellularization cavity; a decellularization treatment module is arranged in a tank body area between the liquid inlet pipe and the liquid outlet pipe; the decellularization treatment module comprises a frequency-adjustable ultrasonic generator and a vibrating screen and is used for providing physical stimulation with different intensities required by decellularization treatment. Through the arrangement of the decellularization processing module comprising the frequency-adjustable ultrasonic generator and the vibrating screen, a user can select ultrasonic waves with different frequencies according to the characteristics of cell materials, and the decellularization requirements of different types of animal materials are met; by arranging the temperature control module, the animal material decellularization system can adjust the temperature in real time, and the problems that in the decellularization process in the prior art, the temperature is inconvenient to monitor, the decellularization efficiency is low, and the decellularization quality is poor are solved.

The application discloses a PMIA / F127 / TA porous membrane and a preparation method thereof. The membrane is prepared by using PMIA polymer as a film-forming main matrix, Pluronic F127 as an additive, and placing the membrane in a TA coagulation bath by adopting the NIPS method. The surface of the membrane presents a uniform, smooth and porous structure, and the cross section of the membrane has a typical asymmetric structure, including a compact epidermis layer on the upper surface, a transition sublayer with finger-like pores and a supporting bottom layer containing a large number of cell cavity structures. With the increase of the Pluronic F127 additive amount, the finger-like sublayer of the membrane gradually changes into a network pore structure composed of connected large pores. Due to the introduction of TA, the segregation phenomenon on the surface of the membrane is improved, the roughness of the film formation is increased, the hydrophilicity is improved, the average pore diameter presents a moderate downward trend, and the porosity presents an upward trend. Therefore, the porous membrane with an ideal pore structure and excellent permeability is prepared.

The invention discloses a negative Poisson's ratio honeycomb composite structural member filled with functional liquid and a preparation method and application thereof, and relates to the technical field of composite material structures, the negative Poisson's ratio honeycomb composite structural member comprises a negative Poisson's ratio honeycomb core layer composed of periodically arranged cell elements with negative Poisson's ratio characteristics; the functional liquid is filled and packaged in the cell element cavities of the negative poisson ratio honeycomb core layer; the composite material skin covers at least one surface of the negative Poisson's ratio honeycomb core layer in a sealed mode, the composite material skin and the core layer jointly form a sandwich structure used for sealing the functional liquid, and the negative Poisson's ratio honeycomb structure is combined with the functional liquid to form the negative Poisson's ratio honeycomb structure. According to the composite structural part, integration of multiple functions is achieved on the basis that the light weight characteristic is kept. The negative Poisson's ratio honeycomb core layer provides deformation stability and energy absorption efficiency superior to those of a traditional honeycomb structure, and the functional liquid packaged in the negative Poisson's ratio honeycomb core layer can provide additional damping dissipation, thermal management or safety protection functions according to the characteristics of the negative Poisson's ratio honeycomb core layer.

A hybrid bioelectronic implantable device containing engineered cells for delivery of therapeutic agents to a subject to treat a medical condition of the subject. The device comprises an implantable device implantable inside the subject's body, wherein the implantable device comprises at least one cell housing containing the engineered cells; and an optical stimulating system within the at least one cell housing, wherein the optical stimulating system is configured to control production of at least one type of therapeutic agents by the engineered cells; wherein the medical condition of the subject comprises one of a sleep disorder, a circadian rhythm disorder, neuro disorders, infertilities, diabetes, obesity, eating disorders, cancers, bone marrow disorders, autoimmune disorders, addictive disorders.

The invention discloses a coniferous wood cross section tracheid cell cavity detection method, device, medium and equipment, and belongs to the technical field of wood identification. Based on the technical scheme of the active learning method, sparse data sampling is carried out in combination with the generative adversarial network, the output of the target detection model is adopted as an SAM prompt strategy, automatic segmentation of the cross section cell cavity of the coniferous wood is achieved, and quantitative anatomical data is obtained. According to the method, by optimizing the data sampling process and enhancing the adaptability of the model, the precision and efficiency of cell cavity segmentation can be effectively improved, and the method can be suitable for any coniferous material cross section microscopic images. The construction of a low-cost coniferous material microscopic image database and the development of a coniferous material tracheid cell cavity detection, segmentation and measurement model are realized, and the problems of difficulty in manual detection, high acquisition and labeling cost and the like caused by complex structure and sampling difficulty of the tracheid cell cavity of the cross section of the coniferous material are solved; and automatic and rapid detection, segmentation and measurement of the coniferous wood tracheid cell cavity are realized.

To provide a suitable means for delivering a therapeutic biomolecule to a patient, wherein a stable and therapeutically effective blood level of the biomolecule occurs in a stable and convenient form over an extended period of time.SOLUTION: Provided is a device for treating a disease in a subject, wherein the subject may have Crohn's disease, ulcerative colitis, primary sclerosing cholangitis, eosinophilic esophagitis, autoimmune hepatitis, the device comprising a cell chamber comprising a population of cells that secrete a biomolecule for delivery to the subject.SELECTED DRAWING: None

The utility model relates to a kind of honeycomb cavity automatic perfusion device, belong to composite material intelligent manufacturing technical field, solve the problem of low efficiency of manual handheld injection gun single-hole perfusion large amount of honeycomb hole in prior art.The utility model includes three-dimensional scanning module (1), truss robot module (2), rotating base (3), track movement structure (4), single-hole perfusion module (5) and whole perfusion module (6);The honeycomb cavity needing to be perfused is scanned by three-dimensional scanning module (1), according to scanning result, single-hole perfusion module (5) or the whole perfusion module (6) is selected to be used, to facilitate the automatic perfusion of the honeycomb cavity of arc honeycomb product or round plate type honeycomb product.The utility model realizes the automatic perfusion of different types of honeycomb product using two kinds of perfusion modules, and improves production efficiency.

The invention relates to the technical field of electrochemical sensors, in particular to a horizontal insertion type pH meter titration cell and application thereof. Comprising a titration cell cavity, a pH electrode horizontally arranged on the side wall of the titration cell cavity, and an electrolyte bottle for providing a reference solution for the pH electrode through a liquid supplementing connecting pipe. The titration cell with the horizontally inserted pH electrode is adopted, so that a sample injection operation space is reserved at the upper opening end of the titration cell, and an operator can directly inject a sample into the titration cell by using a sample injector easily; in the determination process, reagent adding, sodium hydroxide titration, titration cell liquid emptying and cleaning are automatically performed according to program setting, and an operator only needs to add a sample into the titration cell by using a microsyringe. The operation is simple, the result is accurate, the reagent dosage is small, the test cost is low, human interference factors are avoided, and a full-automatic analysis device and method are provided for amino nitrogen determination.

The utility model provides a metal lithium electrolytic bath and belongs to the technical field of electrolytic baths. Comprising a base, a tank body is fixed to the base, an electrolytic tank cavity and a communicating tank cavity are formed in the tank body, the electrolytic tank cavity is communicated with the bottom of the communicating tank cavity to form a U-shaped communicating vessel, an anode is arranged in the middle of the interior of the electrolytic tank cavity, and a cathode is arranged around the anode in the electrolytic tank cavity. A communicating groove cavity is formed in the upper end face of the groove body, a liquid level window is arranged on the side face of the communicating groove cavity, an input pipe is installed in the communicating groove cavity, the top end of the input pipe extends out of the upper end face of the groove body, and a slag discharging pipe is connected to the bottom of the communicating groove cavity. The U-shaped communicating vessel is formed by the electrolytic cell cavity and the communicating cell cavity, so that electrolyte in the electrolytic cell cavity can be conveniently and quickly replaced through the communicating cell cavity, high-intensity current can be supported to pass through by optimizing the structure of the electric row, a good heat dissipation effect is ensured, long-time high-current work is facilitated, and the electrolytic efficiency is improved.

The present invention relates to a multi-pass cell cavity structure capable of quickly performing double-point calibration with a single-concentration calibration gas, which includes a laser, a first cavity mirror with an incident port, a second cavity mirror, a reflector, and a detector. The laser, the reflector, and the detector are located outside the first cavity mirror. The first cavity mirror and the second cavity mirror are arranged opposite to each other, and a double-sided cavity mirror is provided between the first cavity mirror and the second cavity mirror. The emitted light of the laser enters the optical cavity between the first cavity mirror and the second cavity mirror from the incident port according to the incident angle designed by the multi-pass cell, and travels back and forth multiple times in the optical cavity and then exits from the incident port. The emitted light that exits is directed into the detector through the reflector, and the detector is used to measure the change in laser light intensity. This multi-pass cell cavity structure is ingenious. By adding the double-sided cavity mirror, double-point calibration can be achieved based on a single-concentration calibration gas, which can reduce the number of calibration times, improve the calibration rate, and subsequently save the calibration gas used, reduce the usage cost, and enhance the usage experience.

The invention discloses a nano particle measuring device. A nanoparticle measurement device according to one embodiment of the present invention may comprise: a flow cell having a cell cavity formed therein for flowing a liquid sample; a cell seat coupled with the flow cell and supporting the flow cell; the piezoelectric sensor is opposite to the flow cell and is connected with the flow cell; the cell seat cover is arranged opposite to the flow cell, the piezoelectric sensor is located between the cell seat cover and the flow cell, and the cell seat cover is fixed on the cell seat.

The present invention relates to an implantable cell chamber device capable of retaining cells but permitting diffusion of biomolecules. Also disclosed are methods for delivering a therapeutic biomolecule to a subject in need thereof on a continuous or semi-continuous basis, by administering to the subject a cell chamber device comprising cells that secrete the therapeutic biomolecule.