The invention relates to nitrile ester phosphorus potassium and amine actively organic fertilizer. The invention is characterized in that the high quality, high effect and environmental protection fertilizer is produced through wastes such as city organic waste, crop stalk, weed, rice hull, residual bone, residual fur, residual fat, dry cake, chisel, shell and eggshell based on resource use and environmental protection. The invention has the beneficial effect that the reproducible waste comprises a mass of carbohydrates such as fibrin, lignose, starch, polysaccharide, aliphatic acid, ketone, alcohols, protein, nitrile fatty and aminopeptidase, and organically biogenic salts such as organic nitrogen, phosphor, kalium, silicon, sulfur, autunite, magnesium, iron, manganese, copper, boron, zinc and molybdenum. The organic materials are transformed into active nutrients of a plurality of organic enzyme source functions through solidoid fermentation and zymohydrolysis of a plurality of zymogenic combination floras, and the active nutrients can be completely absorbed by crops. Besides, the invention has the advantages of improving the environment of soil, increasing the antibody of plants, decreasing the environmental pollution, increasing the quality of agricultural products and promoting the healthy lives of human being.