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37results about How to "Give full play to the medicinal effect" patented technology

Medical biological hydrogel functional dressing for hemorrhoid and preparation method thereof

The invention relates to the technical field of medical dressing, and specifically relates to a medical biological hydrogel functional dressing for hemorrhoid and a preparation method thereof. The dressing is composed of the following raw materials: glycerin, chitosan quaternary ammonium salt, Chinese lobelia extract, scutellariae barbatae extract, sedum verticallatum extract, smilax glabra extract, stephanotis extract, rabdosia rubescens extract, mint extract, polyhexamethylene guanidine, and the balance being purified water. The dressing other than the auxiliary materials is made of pure traditional Chinese herbals, thus has little irritation, does not have any side or toxic effect, is safe to use, and has the advantages of good permeability and curative effect, fully-exerted effect, long-lasting effect, and difficult relapse. The dressing can be applied to anus to relieve the symptoms of internal hemorrhoid, external hemorrhoid, and mixed hemorrhoid, and symptoms caused by anal fissure / anal fistula surgery such as bleeding, aches, anal pendant expansion, etc. The dressing can also promote hemorrhoid shrinkage, prevent hemorrhoid prolapse, and relieve hyperemia and edema of hemorrhoid mucous membrane, and is capable of being applied to antibacterial nursing of anus diseases such as hemorrhoid.
Owner:DONGGUAN DAQING MEDICAL DEVICES CO LTD +2

Cynanchum otophyllum schneid dispersible tablets and preparation method thereof

The invention discloses a cynanchum otophyllum dispersible tablet and a preparation method thereof, relating to medicines. The cynanchum otophyllum dispersible tablet is made of the following raw materials by weight portions: 50-200 portions of an extract of cynanchum otophyllum total glucoside, 20-100 portions of an disintegrating agent, 1-10 portions of a lubricant and 1-20 portions of a surfactant, wherein, the disintegrating agent is CMS-Na, CCNa, PVPP, L-HPC and dry starch, the lubricant is magnesium stearate or talcum powder or superfine silica gel powder, the surfactant is SDS, sodium hexadecyl sulfate and sodium stearyl sulfate. The preparation method consists of the following steps: 20-200 portions of total glucoside of the cynanchum otophyllum by weight is taken out and sieved with a 100-mesh sieve; 20-100 portions of the disintegrating agent by weight and 1-10 portions of the lubricant by weight are taken out and respectively sieved with the 100-mesh sieve; 1-20 portions of the surfactant by weight is taken out and sieved with a 80-mesh sieve; then the sieved extract, the sieved disintegrating agent, the sieved lubricant and the sieved surfactant are ground and evenly mixed, and then the mixture is sieved with the 80-mesh sieve, and direct compression and sieving are carried out on the sieved mixture to obtain the dispersible tablet. The dispersible tablet has high dissolution and high bioavailability, can fully exert the drug action of the cynanchum otophyllum, and the preparation method is simple and feasible while suitable for industrialized production.
Owner:GUIZHOU UNIV

Transdermal delivery based pharmaceutical composition and preparation method and application thereof

The present invention discloses a transdermal delivery based pharmaceutical composition. The composition comprises a compound as shown in a formula (I) or pharmaceutically acceptable salt thereof, a macromolecular dispersing carrier material, a hot melting protecting agent and an optional fluxing agent. A preparation method of the transdermal delivery based pharmaceutical composition comprises thesteps of micronizing the compound as shown in the formula (I) or the pharmaceutically acceptable salt thereof, the macromolecular dispersing carrier material and the hot melting protecting agent, optionally adding the fluxing agent, mixing the components uniformly, and performing hot melting extrusion and micronizing to obtain microparticles of the compound as shown in the formula (I) or the pharmaceutically acceptable salt thereof. In addition, the invention provides an application of the pharmaceutical composition. The transdermal delivery based pharmaceutical composition can enable the compound as shown in the formula (I) to be quickly absorbed, so that the purpose of calming before anesthesia is achieved, breathing is not affected, and the adverse psychological effects on children dueto intramuscular injection or intravenous injection are avoided. Meanwhile, the pharmaceutical composition also can be used for preventing and/or treating hyperactivity.
Owner:YICHANG HUMANWELL PHARMA

Medical biological dressing suppository for treating hemorrhoid

The invention discloses a medical biological dressing suppository for treating hemorrhoid. The medical biological dressing suppository is prepared from a medicinal component and a suppository matrix, wherein the medicinal component is prepared from the following components in parts by weight: 18-20 parts of golden cypress, 12-15 parts of radix sophorae flavescentis, 12-15 parts of purslane, 5-8 parts of gleditsia sinensis, 6-8 parts of dried ginger, 8-12 parts of rheum officinale, 5-8 parts of verdigris, 8-10 parts of borneol, 3-6 parts of realgar, 15-18 parts of bidens pilosa L, 12-15 parts of rhizoma smilacis glabrae, 8-10 parts of common cnidium fruits, 5-8 parts of cortex dictamni, 5-8 parts of curcuma zedoary, 8-10 parts of folium artemisiae argyi, 6-8 parts of dried alum, 12-15 parts of blue salt and 6-8 parts of Sichuan pepper; the suppository matrix is prepared from the following components in percentage by weight: 22% of chitosan, 8% of carbopol and 70% of polyethylene glycol. The medical biological dressing suppository is prepared according to a traditional Chinese medicine formula so as to be free of toxic or side effect and capable of ensuring that hemorrhoid is not easy to recur; the suppository is used as the dosage form so as to have the advantages of high disintegration speed, absorption completeness, no injury to mucous membranes and cleanness, and effects are rapid to take; in addition, the medical biological dressing suppository is good in curative effect, long in acting time and favorable in curative effect for hemorrhage, swell, pain, astriction and the like caused by internal hemorrhoid, external hemorrhoid and mixed hemorrhoid.
Owner:安徽承庆堂国药股份有限公司

Tapentadol pharmaceutical composition for transdermal administration as well as preparation method and application of pharmaceutical composition

The invention discloses a pharmaceutical composition for transdermal administration. The pharmaceutical composition contains tapentadol or a pharmaceutically acceptable salt thereof, a polymer dispersion carrier material, a hot-melt protective agent and an optional solubilizer. A preparation method of the pharmaceutical composition includes the following steps: mixing the tapentadol or the pharmaceutically acceptable salt thereof, the polymer dispersion carrier material, the hot-melt protective agent and the optional solubilizer, performing hot-melt extrusion, and performing micronization to obtain the microparticles of the tapentadol or the pharmaceutically acceptable salt thereof. The pharmaceutical composition for the transdermal administration can make the tapentadol or the pharmaceutically acceptable salt thereof rapidly absorbed, and achieve the purpose of sedation before anesthesia without affecting breathing, thereby avoiding the adverse psychological effects of intramuscular injection or intravenous injection acupuncture on children; and at the same time, the pharmaceutical composition can also be used to prevent and/or treat and delay the development of Parkinson disease.
Owner:YICHANG HUMANWELL PHARMA

Sufentanil pharmaceutical composition for transdermal administration as well as preparation method and application of composition

The invention discloses a pharmaceutical composition for transdermal administration. The pharmaceutical composition comprises sufentanil or a pharmaceutically acceptable salt thereof, a polymer dispersion carrier material, a hot-melt protective agent and an optional solubilizer. The pharmaceutical composition for transdermal administration is obtained by the following steps: mixing the sufentanilor the pharmaceutically acceptable salt thereof, the polymer dispersion carrier material, the hot-melt protective agent and the optional solubilizer, performing hot-melt extrusion and micronization toobtain microparticles of the sufentanil or the pharmaceutically acceptable salt of the sufentanil. In addition, the invention provides a preparation method and application of the above pharmaceuticalcomposition. According to the pharmaceutical composition for transdermal administration, the sufentanil can be quickly absorbed, the purpose of treating postoperative pain without affecting breathingcan be achieved, and adverse psychological effects of intramuscular injection or intravenous injection acupuncture on patients can be avoided; and at the same time, the pharmaceutical composition canbe used to prevent and/or treat postherpetic neuralgia.
Owner:YICHANG HUMANWELL PHARMA

Alfentanil pharmaceutical composition for transdermal administration as well as preparation method and application of pharmaceutical composition

The invention provides an alfentanil pharmaceutical composition for transdermal administration as well as a preparation method and application of the pharmaceutical composition. The pharmaceutical composition for transdermal administration disclosed by the invention comprises alfentanil or a pharmaceutically acceptable salt thereof, a polymer dispersion carrier material, a hot-melt protective agent and an optional solubilizer, the pharmaceutical composition is obtained by the steps of mixing the alfentanil or the pharmaceutically acceptable salt thereof, the polymer dispersion carrier material, the hot-melt protective agent and the optional solubilizer, and performing hot-melt extrusion and micronization to obtain microparticles of the alfentanil or the pharmaceutically acceptable salt ofthe alfentanil. In addition, the invention provides the preparation method and application of the above pharmaceutical composition. According to the pharmaceutical composition for transdermal administration, the alfentanil or the pharmaceutically acceptable salt thereof can be quickly absorbed to achieve the purpose of pain anesthesia in treating without affecting breathing, and avoids the adversepsychological effects brought to patients by intramuscular injection or intravenous injection; and at the same time, the pharmaceutical composition can also be used to prevent and / or treat skin itching.
Owner:YICHANG HUMANWELL PHARMA

Pharmaceutical composition of morphin-6-glucuronid for transdermal administration and preparation method and application of pharmaceutical composition

The invention discloses a pharmaceutical composition for transdermal administration. The pharmaceutical composition comprises morphin-6-glucuronid or a pharmaceutically acceptable salt thereof, a polymer disperse carrier material, a hot melt protecting agent and an optional fluxing agent, wherein the pharmaceutical composition for transdermal administration is prepared by mixing the morphin-6-glucuronid or the pharmaceutically acceptable salt thereof, the polymer disperse carrier material, the hot melt protecting agent and the optional fluxing agent, and then carrying out hot melt extrusion and micronization to obtain particles of the morphin-6-glucuronid or the pharmaceutically acceptable salt thereof. In addition, the invention further provides a preparation method and application of thepharmaceutical composition. According to the pharmaceutical composition for transdermal administration, the morphin-6-glucuronid or the pharmaceutically acceptable salt thereof can be quickly absorbed to achieve the target of postoperative analgesia without affecting breathing, so that an adverse psychological effect to a patient caused by acupuncture of intramuscular injection or intravenous acupuncture is avoided; and meanwhile, the pharmaceutical composition can also be used for preventing and / or treating lumbar and cervical diseases of the patient.
Owner:YICHANG HUMANWELL PHARMA

Cynanchum otophyllum schneid dispersible tablets and preparation method thereof

The invention discloses a cynanchum otophyllum dispersible tablet and a preparation method thereof, relating to medicines. The cynanchum otophyllum dispersible tablet is made of the following raw materials by weight portions: 50-200 portions of an extract of cynanchum otophyllum total glucoside, 20-100 portions of an disintegrating agent, 1-10 portions of a lubricant and 1-20 portions of a surfactant, wherein, the disintegrating agent is CMS-Na, CCNa, PVPP, L-HPC and dry starch, the lubricant is magnesium stearate or talcum powder or superfine silica gel powder, the surfactant is SDS, sodium hexadecyl sulfate and sodium stearyl sulfate. The preparation method consists of the following steps: 20-200 portions of total glucoside of the cynanchum otophyllum by weight is taken out and sieved with a 100-mesh sieve; 20-100 portions of the disintegrating agent by weight and 1-10 portions of the lubricant by weight are taken out and respectively sieved with the 100-mesh sieve; 1-20 portions ofthe surfactant by weight is taken out and sieved with a 80-mesh sieve; then the sieved extract, the sieved disintegrating agent, the sieved lubricant and the sieved surfactant are ground and evenly mixed, and then the mixture is sieved with the 80-mesh sieve, and direct compression and sieving are carried out on the sieved mixture to obtain the dispersible tablet. The dispersible tablet has high dissolution and high bioavailability, can fully exert the drug action of the cynanchum otophyllum, and the preparation method is simple and feasible while suitable for industrialized production.
Owner:GUIZHOU UNIV
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