54results about How to "Good puncture effect" patented technology

The invention provides a radio frequency melting electrode for an otitis media minimally invasive surgery and a using method of the radio frequency melting electrode. The radio frequency melting electrode comprises a handle and an electrode which are mutually connected, wherein the electrode adopts a tubular structure, and comprises an inner tube electrode and an outer tube electrode; the inner tube electrode and the outer tube electrode are connected with two poles of a power source; the tube body of the outer tube electrode sleeves the tube body of the inner tube electrode; the headend of the outer tube electrode and the headend of the inner tube electrode are in the same direction and are exposed to form the electrode headend of the electrode; the external surface of the inner tube electrode is an insulation surface; and the tube body of the inner tube electrode and the tube body of the outer tube electrode are mutually isolated, and the headends of the inner tube electrode and theouter tube electrode can be electrically conducted through normal saline, so that a plasma field is formed by the electrode headend to perform melting and drilling on tympanic membrane tissue. A thinking set of a conventional high-temperature puncturing surgery manner of mechanical puncturing, electric burning or laser and the like is broken through, low-temperature plasma principle is utilized toform the plasma field in the electrode headend, and melting and drilling are performed on the tympanic membrane tissue under a low temperature, so that the efficiency and the treatment effect of theotitis media minimally invasive surgery are improved.

Provided are a microneedle and a microneedle array which have both aspects of safety and easiness to use and can administer a predetermined dose of a medical agent without causing a pain by smoothly running into the skin surface layer of a patient,

• • the microneedle comprising a frustum and a forward end portion thereon, having a forward end apex angle in the range of 15 to 60° and a forward end diameter in the range of 1 to 20 μm and satisfying the following expression (1),

H/D≧5  (1)

• • (H: Height of the whole, D: Diameter of bottom surface of the frustum).

The invention provides a puncture-preventing indwelling needle. The puncture-preventing indwelling needle comprises a catheter base, a needle file, a needle tube and a protection mechanism, wherein the needle file sleeves the catheter base in a sliding manner; the needle tube is mounted to the needle file, and the needle point can penetrate through the catheter base; the protection mechanism is arranged between the catheter base and needle file, and is composed of a protection base and a protection plate mounted on the protection base, the protection base is provided with a protection base body allowing the needle tube to pass through, and an accommodating cavity for accommodating part of the needle tube is formed in the protection base body; the protection plate is provided with a protection plate body, a baffle plate accommodated in the accommodating cavity is formed at one end of the protection plate body, the baffle plate has the first state of pushing against the needle tube and a second state of sheltering the needle point, a support structure is arranged in the accommodating cavity, the support structure applies a supporting force to the needle tube, and the direction of the supporting force is opposite to that of the resisting force applied by the baffle plate. For the puncture-preventing indwelling needle, the support structure applies the supporting force to the needle tube, the direction of the supporting force is opposite to that of the resisting force applied by the baffle plate, so that the needle tube has small possibility of deformation under the pushing and pressing of the baffle plate.

The invention relates to a Parallel output fastening device with puncture clamp and adjustable double shaft, which comprises a brushless electric machine, a striking block and two output shafts placed paralleling in turn. The brushless electric machine connects and drives gearbox. The gearbox drives striking block, and the striking block drives striking axle. An output terminal of the striking axle is connected to face gears ranged side by side. The face gear drives two face gear shafts respectively. The two face gear shafts keep synchronous operation completely and are connected to two output shafts ranged side by side. The device make it come true that two fastening nuts really are tightened and two output shafts of the device are connected to each other by gear mechanism rigidly without rotation speed difference, which can achieve the optimal effect of puncture.

The invention discloses a CT (computed tomography) guidance percutaneous puncture three-dimensional positioning frame. The CT guidance percutaneous puncture three-dimensional positioning frame is provided with a left camera and a right camera, a picture is converted by a sensor to a digital signal recognized by a controller so as to accurately locate a locator; moreover, the entire puncture process of a puncture needle is monitored, so that a purpose of precise puncturing can be realized; and the CT guidance percutaneous puncture three-dimensional positioning frame is provided with four contactors which are accurately located by the locator, so that the fixture in contact can be improved, the pain of a patient in the puncturing process can be alleviated, more precision in location during the percutaneous puncture process can be realized, the focal cells can be accurately destroyed, the normal tissue on the periphery of a focus is not damaged, and a good puncture effect can be realized. By adopting the CT guidance percutaneous puncture three-dimensional positioning frame, a focal target point can be accurately punctured, the focal tissues can be more effectively killed, and the unnecessary injury and complication can be reduced. The CT guidance percutaneous puncture three-dimensional positioning frame has the advantages of more accuracy in target point location, more convenience and rapidness in operation, capability of reducing the repeated puncturing and complication and the like.

The invention discloses an ultrasound-guided puncture positioning guide device. The ultrasound-guided puncture positioning guide device comprises a guide device body for installing a positioning plate on an ultrasonic probe, a first sliding groove with scales is arranged on the positioning plate, and a needle sleeve is assembled in the sliding groove; and the ultrasonic probe is detachably installed on the positioning plate. According to the ultrasound-guided puncture positioning guide device, an auxiliary laser positioning device is adopted, after the ultrasound position is determined, the scope where a puncture needle way can be built is determined through the laser positioning device, the position of the needle way can be displayed through a display screen all the time, and therefore the good auxiliary effect is provided for a doctor; a positioning plate structure matched with the probe is arranged so as to be capable of being matched with an ultrasound imaging device, under indication of puncture target spots displayed in the display screen of the ultrasound imaging device, the puncture position is precisely given through the scales on the positioning plate, and the puncture process can be implemented with a purpose; and the overall set of device can be applied to multiple positions on the body surface and can have the fixing effect on the ultrasonic probe, so that the overall puncture process is premise and simple, and the good puncture effect is achieved.

The invention discloses a stem cell exosome microneedle patch for removing freckles and wrinkles. The stem cell exosome microneedle patch comprises a microneedle and a waterproof backing layer for fixing the microneedle, wherein the microneedle is obtained by curing a needle tip solution and a needle body solution, the needle tip solution comprises a stem cell exosome, astaxanthin, trehalose, chitosan, bovine serum albumin and a phosphate buffer solution; and the needle body solution is prepared from PVP K30, PEG 400, squalane and sterile water. The microneedle patch disclosed by the inventioncan penetrate through a skin cuticle barrier, a novel administration path is provided for macromolecular drugs, and the problem of transdermal absorption of an exosome repair solution is solved. Themicroneedle patch can slowly release exosome repair solution, so that the absorptivity of an organism is improved. The microneedle patch has good puncture property, solubility and biological activity,is simple to operate and easy to store, and can be produced on a large scale.

The invention provides ceramic slurry, a ceramic diaphragm and a lithium ion battery. The ceramic slurry includes: a layered inorganic material; nano ceramic particles; a binder; an auxiliary agent; and water. The ratio of the radius to the thickness of the layered inorganic material is 150-400. The ceramic slurry is strong in stability, can meet the actual production requirements, and can prolongthe growth path of lithium dendrites in the lithium ion battery, so that the lithium dendrites puncture resistance of the ceramic diaphragm is good; meanwhile, the ceramic coating formed by the ceramic slurry can enable the thermal shrinkage degree of the ceramic diaphragm to be small and the stability to be good.

The invention discloses an endoscopic biopsy apparatus which comprises a handle assembly, an outer tube, a limiting piece, a needle tubing and an inner core wire. The handle assembly is composed of an adjustment handle, an outer tube handle, a limiting ring, an operation handle, a scale core rod, a needle tubing operation handle and an inner core wire control handle. The adjustment handle, the limiting ring and the operation handle are all arranged on the scale core rod and connected into a whole through the scale core rod. The outer tube handle is arranged in the adjustment handle and connected with the outer tube. The outer tube is connected with the scale core rod. The needle tubing operation handle is connected with the operation handle in a screwed mode. The operation handle is connected with the limiting piece in an inserted mode. The needle tubing is composed of a needle point section at the far end and a needle body section behind the needle point section. The needle tubing is located in the outer tube. The needle point section penetrates out of the far end of the outer tube. The needle body section is fixedly connected with the needle tubing operation handle. The inner core wire penetrates into the needle tubing. The far end of the inner core wire goes beyond the needle point end, and the near end of the inner core wire is connected with the inner core wire control handle. The biopsy operation is greatly simplified, the success rate and safety of operation are improved, operators can be easily trained, and wide promotion is easy.

The invention belongs to the technical field of lithium ion batteries, and particularly relates to a high-safety lithium ion battery electrolyte, which comprises an organic solvent, a lithium salt andan additive, wherein the additive comprises a main additive and an auxiliary additive, and the main additive is at least one of a pyrrole ionic liquid and a phosphorus-containing ionic liquid. The major characteristic of the lithium ion battery electrolyte is that the ionic liquid additives are combined, so that a formed protective film has better high voltage resistance, the side reaction loss of the electrolyte is effectively reduced, and the cycle life and the electrode stability of the battery are improved; and the thermal runaway rate of the battery is delayed through the thermal conductivity of the electrolyte, especially a flame retardant element or group is introduced, the flame retardant effect of the battery is improved, and the passing of puncture performance and weight impacttests of the battery is more facilitated.

The invention discloses a heptamethyl cyanine dye-crosslinked tetracyclic amine chelating agent conjugate. The conjugate comprises a heptamethyl cyanine dye (HMCD) group coupled by a crosslinking agent group L and a crosslinked tetracyclic amine (CTC) chelating agent residue R; the cross-linking agent group L is composed of zero or one or more amino acid residues; the residue R of the cross-linked tetracyclic amine (CTC) chelating agent is a group consisting of CB-TE2A or DiAmSar or a derivative of the CB-TE2A or DiAmSar; and the residue R of the cross-linked tetracyclic amine (CTC) chelating agent is combined with <64>Cu. According to the scheme, the copper compound containing DZ-1-(L)-CTC can provide improved serum stability compared with copper compounds known in the past, and meanwhile, the tumor targeting property is reserved, and good imaging quality is provided.

The invention discloses a side-lying auxiliary device for CT inspection and puncture. The side-lying auxiliary device comprises a base, a bed plate, a floating plate, a first splint, a second splint,a first driving mechanism and a second driving mechanism; wherein the bed plate is horizontally arranged and relatively fixed on the upper side of the base; a first through hole and a second through hole which penetrate the bed plate in the vertical direction are formed on the bed plate; the floating plate which is horizontally positioned and capable of sliding in the vertical direction is arranged between the base and the bed plate; the first splint and the second splint which are vertically positioned are relatively arranged on the floating plate and capable of relatively sliding in the width direction of a bed body; the first driving mechanism drives the floating plate to slide between a first position and a second position in the vertical direction; and the second driving mechanism drives the first splint and the second splint to move towards or against each other in opposite directions when the floating plate is located in the second position. The side-lying auxiliary device for CT inspection and puncture provided by the invention can assist a patient to keep lying on one side and ensure better effects in CT inspection and puncture, and is simple in structure and convenient for use.

The invention discloses an auxiliary device for coronary angiography, and mainly relates to the field of coronary angiography devices. The auxiliary device includes a puncture auxiliary device, a guide wire auxiliary device, a postoperative fixing device and a supporting frame body. The puncture auxiliary device, the guide wire auxiliary device and the postoperative fixing device are all arranged on the supporting frame body. The puncture auxiliary device comprises a pressure detection cover plate and a limiting rod; the guide wire auxiliary device comprises a guide wire tube and a tachometer wheel, wheel grooves are symmetrically formed in the side wall of the end of the outer side of the guide wire tube, and the tachometer wheel is arranged in the wheel grooves. The auxiliary device has the beneficial effects that a doctor can be helped to perform a coronary angiography operation more conveniently, so that the doctor does not depend on own experience to operate during the operation, the scientization and datamation of the operation are further guaranteed, and the harm of the coronary angiography operation to a patient is further reduced.

The invention relates to a composition with anti-inflammatory and analgesic effects, a soluble microneedle patch and a preparation method of the soluble microneedle patch. The composition with the anti-inflammatory and analgesic effects comprises the following components in parts by weight: 0.5-2 parts of capsaicin, 3-10 parts of methyl salicylate, 5-20 parts of a cannabis sativa leaf extract, and5-20 parts of paeonol. The soluble microneedle patch consists of a needle tip, and a substrate; the needle tip is prepared from the composition with the anti-inflammatory and analgesic effects, a solubiliser, and a microneedle framework material; and the composition with the anti-inflammatory and analgesic effects, the solubiliser and the microneedle framework material are proportioned in a massratio of 1 to 0.1-2 to 8-20. The soluble microneedle patch has good mechanical properties and a relatively high intradermal dissolution rate; and moreover the soluble microneedle patch has good anti-inflammatory and analgesic effects.

The invention provides a ceramic micro-needle crystal plate. The crystal plate is provided with a surface and a bottom surface; the surface is provided with needle-shaped bulges which are distributed in an array form; the crystal plate is prepared from the following components in percentage by weight: 60 percent to 80 percent of SiO2, 0.05 percent to 5 percent of Al2O3, 0.5 percent to 10 percent of LiO2, 0.1 percent to 5 percent of K2O, 0.1 percent to 5 percent of Na2O and 0.01 percent to 0.5 percent of Ag2O. The invention further provides a preparation method of the ceramic micro-needle crystal plate. The method comprises the following steps: (1) providing a parent plate and machining the parent plate to obtain reversed needle-shaped concave parts which are distributed in the array form; (2) mixing crystal plate raw materials and coating the surface of a wood plate with a raw material mixture; (3) sintering and molding the raw material mixture to obtain the crystal plate; (4) separating the parent plate from the crystal plate and cutting the crystal plate into needed sizes.

The invention discloses an extraction and suction integrated percutaneous endoscope puncture biopsy instrument which structurally comprises an extraction and suction device, a limit component, an outer tube, an outer tube handle, a syringe, a syringe handle and an inner core wire, the syringe is arranged into an inner cavity of the outer tube, the syringe comprises a needle tip section and a needle body section, the needle tip section penetrates the far end of the outer pipe, the needle body section penetrates the near end of the outer pipe and is connected with the syringe handle, the near end of the syringe handle is connected with the extraction and suction device, a limit component is rotatably connected with the near end of the outer tube handle, and a slider is arranged on the syringe handle and slidably connected with the limit component. The biopsy instrument can meet requirements of any ultrasound endoscope mediation of digestive tracts and tracheae and further can be used fora non-ultrasonic through the scope, deep puncture biopsy, liquid extraction and the like under direct vision are achieved, puncture operation is simplified to a great extent, and operation safety isimproved.

The invention discloses a concave natural rubber coated pad and a production technology thereof. The concave natural rubber coated pad comprises a natural rubber layer and a coating layer, the natural rubber layer comprises natural rubber, an accelerator, sulfur, stearic acid, zinc oxide, heavy calcium carbonate, titanium dioxide, iron oxide red, an antioxidant 264 and Vaseline, and the accelerator in the natural rubber layer includes at least one of an accelerator TRA and an accelerator TMTD; and the coating layer includes one of an FEP layer, a PTFE Layer and an ETFE layer. The concave natural rubber coated pad has the advantages of good supporting effect, good puncture resistance and good resilience.

To provide a leading-end tip for a catheter, having exceptional piercing properties. A leading-end tip 10 for a catheter has a first member 100 that is connected to the distal end of a catheter 2, anda second member 200 that is fixed so as to protrude in the axial direction from the distal-end surface of the first member 100. The material of the second member 200 is harder than the material of the first member 100, and formed in the first member 100 and/or the second member 200 is at least one anchoring protrusion 141 for engaging with the other of the first member 100 and the second member 200.

The invention discloses a multi-layer plastic film blowing method. The method comprises the steps that S1, hot melt adhesive resin of different materials or colors is subjected to melting treatment; S2, a first film bubble is formed in a molten material under the action of gas output by a die head assembly; S3, an anti-blocking agent solution is sprayed on the inner surface of the first film bubble for the first time, and a first film is formed under the action of a first traction assembly; S4, multi-stage heating is carried out on the first film; S5, the first film is aerated and subjected to secondary blow-up treatment, and the anti-blocking agent solution is sprayed on the inner surface of a second film bubble for the second time; and S6, a second film is subjected to online edge cutting, opening, film separating and winding operation, and waste obtained after edge cutting is recycled through a matched recycling device so that the waste can be rotated into a feeding assembly to be secondarily utilized.

The invention belongs to the technical field of waterproof materials and relates to a double root-resistant high polymer waterproof coiled material and a preparation method thereof. The composite material is prepared from the following components in weight percentage: 50% of modified asphalt; 5.6% of solvent type high polymer modified rubber; 15% of rubber filling oil; 15% of resin additive; 9% offiller; 5% of anti-aging agent; and 0.4% of chemical root retarder. The novel high polymer waterproof coiled material prepared by adopting a chemical and physical root blocking method has good puncture resistance and tear resistance; the waterproof coiled material can be effectively protected from being influenced by cross operation, and has physical root resistance and chemical root resistance,so that two functions of root resistance and water resistance are completed at a time; and the waterproof coiled material has reliable lap joint and adhesion performance.