The invention relates to a vehicle transmission shaft straightening device, which comprises a base, guide rails, a sliding support mechanism, a measurement mechanism, a stand column mechanism and a straightening mechanism, wherein the guide rails are arranged on the base, the sliding support mechanism is connected with the guide rails in a sliding mode, the measurement mechanism is arranged on the sliding support mechanism, the stand column mechanism is arranged on the base, and is arranged on one side of the guide rails, the straightening mechanism is arranged on the stand column mechanism, a transmission shaft is arranged on the sliding support mechanism, the straightening mechanism downwardly moves to a position where is be about to contact with the upper surface of the transmission shaft, the measurement mechanism is contacted with the lower surface of the transmission shaft, and rotates the transmission shaft and pushes the sliding support mechanism, and the straightening mechanism straightens pressure of the transmission shaft through reading of the measurement mechanism. Compared with the prior art, the vehicle transmission shaft straightening device has the advantages that the vehicle transmission shaft straightening device improves straightening precision, and is simple in structure and convenient to operate and the like.