The invention discloses a zero-discharge process for treating desulfurization wastewater by integrating low-temperature flash evaporation, concentration and crystallization and concentrated liquid reflux, which comprises a flue gas heat exchange system, a low-temperature multi-effect evaporation system, a condensate water system, a solid-liquid separation system, a filtrate reflux and electric heating system and a PH (potential of hydrogen) regulating system, the flue gas heat exchange system, the low-temperature multi-effect evaporation system, the solid-liquid separation system and the filtrate backflow and electric heating system are sequentially connected, the flue gas heat exchange system and the condensate water system are connected with the low-temperature multi-effect evaporation system, and the filtrate backflow and electric heating system is connected with the low-temperature multi-effect evaporation system. According to the invention, a low-temperature flash evaporation, concentration and crystallization integrated and concentrated liquid reflux process is adopted, and a traditional high-temperature flue gas drying process is cancelled, so that not only is the disadvantage of insufficient two-effect and three-effect evaporation capacity of a low-temperature multi-effect flash evaporation system overcome, but also the problems of high equipment investment cost and low energy consumption caused by high-temperature flue gas drying of concentrated water are solved. The operation and maintenance cost is high; and crystallized salt is disposed.