The invention provides a profile modification agent for amphion jelly. The profile modification agent comprises the following components by weight percent: 0.1%-0.3% of amphion polymer, 0.1%-0.3% of compound cross-linking agent and the balance of water, wherein the molecule weight of the amphion polymer is above 1500 ten thousand. The compound cross-linking agent is prepared by a method comprising the following steps: firstly, adding phenol and formaldehyde in an enamel reaction kettle with a stirrer at a mass ratio of 1:1, heating and raising the temperature to 60 DEG C, then adding triethanolamine so that the phenol and formaldehyde are reacted to generate a mixture of monohydroxymethyl phenol, dihydroxymethyl phenol and trihydroxymethyl phenol for later use; next, adding sodium dichromate and thiourea in the reaction kettle with the stirrer at a weight ratio of 1:1, adding hydrochloric acid and a mixture of sodium acetate and sodium malonate which are at a weight ratio of 1:1 to react for 12 hours for later use; and mixing the products obtained from the former two steps at an isovolumetric ratio, and adding absolute ethyl alcohol for evenly stirring so as to obtain the compound cross-linking agent. According to the invention, the glue-forming property and glue-forming strength of the jelly profile modification agent in high-hypersalinity oil field water are improved, and the validity of the profile modification of the oil field is prolonged.