The invention discloses a production process tail gas cleaning treatment device, which relates to the technical field of tail gas treatment, and comprises a purification box, a gas inlet mechanism, a spraying mechanism, a backflushing mechanism, a backflow preheating mechanism, a discharge box, a dehumidification adsorption mechanism, a backflow dehumidification mechanism and an absorption liquid discharge mechanism, a plurality of evenly-distributed electric heating wires are installed at the bottom end of the interior of the purification box, and a gas inlet mechanism used for tail gas treatment is installed in the purification box. Cold waste gas can be preheated through a backflow preheating mechanism, so that the absorption treatment effect on the waste gas is improved, and when the device is used, the waste gas can be recycled. And hot air in the purification box can enter the heat return pipe and enter the air inlet pipe through the top end of the heat return pipe, so that the hot air is in contact with cold air in the air inlet pipe, the heat transfer effect is achieved, the effect of preheating cold waste gas is achieved, resources consumed by subsequent air heating are reduced, and the neutralization reaction effect with absorption liquid is improved.