The invention belongs to the technical field of high-rise building pipeline laying, and particularly relates to a segmented-assembled high-rise building tube well vertical pipeline structure and a construction method thereof. The construction method comprises the steps of tube well vertical pipe data collection, tube well vertical pipe module structure design checking calculation, tube well vertical pipe deepening design, vertical pipe module factory manufacturing, vertical pipe module transportation, field installation construction preparation, vertical pipe module field hoisting, welding connection between modules and welding flaw detection acceptance. According to the construction method of the segmented-assembled high-rise building tube well vertical pipeline, modular factory machiningis adopted, the manufacturing precision is high, the machining quality is good, the efficiency is high, modular field installation is achieved, the hoisting frequency is small, field welding is small, construction is easy and convenient, the efficiency is high, the quality is good, the field construction safety is good, the operation risk in the construction process is low, the material loss is small, the construction period is short, the economic efficiency is good, and energy conservation and environmental protection are achieved.