The invention discloses an agricultural pesticide and liquid fertilizer spraying device which comprises a trolley, a liquid blending device, a supporting rod, a liquid spraying device, a liquid suction pump, liquid suction hoses and a controller. A pesticide blending box is arranged at the right side of the top of the trolley, the supporting rod is arranged at the left side of the top of the trolley, and the liquid spraying device is arranged on the supporting rod; and the liquid suction pump is arranged on the trolley, the left side and the right side of the liquid suction pump are both connected with the liquid suction hoses, the inlet end of the liquid suction hose at the right side is communicated with the bottom of the liquid blending device, the outlet end of the liquid suction hose at the left side is communicated with the bottom of the supporting rod, and the liquid blending device, the liquid spraying device and the liquid suction pump are electrically connected with the controller arranged on the side face of the trolley. The spraying device is simple in structure, convenient to use, capable of meeting the requirements for fertilization and pesticide spraying, uniform in spraying, large in spraying range, capable of achieving accurate spraying, capable of improving the working efficiency, capable of saving manpower and reducing the labor cost, safe in operation and suitable for application and popularization.