The invention discloses a nutritional diet meal replacement biscuit. The biscuit comprises the following components in parts by weight: 100 parts of low-gluten wheat flour, 20 parts of refined vegetable oil, 10.5 parts of Chinese wolfberry fruits, 2 parts of shortening, 4 parts of oat flour, 5.25 parts of red beans, 5 parts of quinoa flour, 8.4 parts of lotus leaves, 2 parts of galangal, 8 parts of skimmed milk powder, 20 parts of polydextrose, 2.65 parts of coix seeds, 1 part of white sesame, 1 part of wheat germ, 0.25 part of watermelon powder, 0.5 part of table salt, 3 parts of fresh eggs,10 parts of maltitol, 5 parts of buckwheat powder, 5 parts of inulin, 1 part of oatmeal, 2.5 parts of corn starch, 0.65 part of sodium bicarbonate, 2 parts of vitamin C, 0.035 part of vitamin B3, 0.0035 part of vitamin B1, 0.05 part of sucralose, 0.18 part of pyrophosphoric acid, 0.25 part of soybean lecithin, 0.15 part of vanillin and 0.05 part of cheese powder. The biscuit can nurse the body, prevent and treat obesity and condition hypertension, hyperglycemia and hyperlipidemia from the aspect of nutritional diet.