The invention discloses a tire vulcanization production control system and an operative plan execution method. According to a vulcanization production control process, production on-line integrated control system and method are provided in the hope of realizing automatic management of vulcanization production and realizing operative plan formulation and control system configuration meeting the requirements of the vulcanization production process so as to improve the vulcanization production efficiency, and control and reduce energy consumption during batch production. The tire vulcanization production control system comprises a database server, an application server, a client working station, an interface management server, an upper computer and a computer network. A technological parameter setting module, an algorithm parameter setting module, a production order form information receiving module, a production process real-time data receiving module, a daily production plan formulation module, an operative plan formulation module, an operative plan result release module, a technological parameter loading module and a production process monitoring module are arranged on the application server.