156 results about "Cell shape" patented technology

Several inventions are disclosed. A cell architecture using hexagonal shaped cells is disclosed. The architecture is not limited to hexagonal shaped cells. Cells may be defined by clusters of two or more hexagons, by triangles, by parallelograms, and by other polygons enabling a variety of cell shapes to be accommodated. Polydirectional non-orthogonal three layer metal routing is disclosed. The architecture may be combined with the tri-directional routing for a particularly advantageous design. In the tri-directional routing arraingement, electrical conductors for interconnecting terminals of microelectronic cells of an integrated circuit preferrably extend in three directions that are angularly displaced from each other by 60°. The conductors that extend in the three directions are preferrably formed in three different layers. A method of minimizing wire length in a semiconductor device is disclosed. A method of minimizing intermetal capacitance in a semiconductor device is disclosed. A novel device called a "tri-ister" is disclosed. Triangular devices are disclosed, including triangular NAND gates, triangular AND gates, and triangular OR gates. A triangular op amp and triode are disclosed. A triangular sense amplifier is disclosed. A DRAM memory array and an SRAM memory array, based upon triangular or parallelogram shaped cells, are disclosed, including a method of interconnecting such arrays. A programmable variable drive transistor is disclosed. CAD algorithms and methods are disclosed for designing and making semiconductor devices, which are particularly applicable to the disclosed architecture and tri-directional three metal layer routing.

Methods and apparatus are disclosed for determining the volume, hemoglobin concentration, maturity and cell shape of mammalian red blood cells in a sample and simultaneously monitoring system standardization.

A method for manufacture of application specific solar cells includes providing and processing custom design information to determine at least a cell size and a cell shape. The method includes providing a transparent substrate having a back surface region, a front surface region, and one or more grid-line regions overlying the front side surface region. The one or more grid regions provide one or more unit cells having the cell size and the cell shape. The method further includes forming a layered structure including photovoltaic materials overlying the front surface region. Additionally, the method includes aligning a laser beam from the back surface region to illuminate a first region within the one or more grid-line regions, subjecting a first portion of the layered structure overlying the first region to the laser beam to separate the first portion of the layered structure from the first region, and scanning the laser beam along the one or more grid-line regions to cause formation of one or more unit cells having the cell size and cell shape. The method further includes transferring the one or more unit cells.

Methods and apparatus are disclosed for determining the volume, hemoglobin concentration, maturity and cell shape of mammalian red blood cells in a whole blood sample and simultaneously monitoring system standardization. Methods for distinguishing red blood cells from other cellular particles, prior to the red blood cell analysis are also disclosed. Red blood cells are passed through a beam of light in single file at a selected wavelength, obtaining an initial cytogram by means of the resultant magnitude of one light loss signal and one forward angle light scatter signal at a selected angular interval and a third side angle light scatter or two forward angle light scatter signals at a selected angular intervals and a third side-angle light scatter signal, projecting the cytogram, point by point, onto a pre-calibrated 3-dimensional surface containing grid lines of volume and hemoglobin concentration and determining accurate values of cell volume and hemoglobin concentration.

Provided are methods for the selection and regulation of the mechanical properties of 2D or 3D biocompatible substrates or tissue microenvironments as a technique to regulate in vitro differentiation, cell shape and / or lineage commitment of anchorage-dependent cells, such as mesenchymal stem cells into, e.g., neurogenic-, myogenic-, and osteogenic-type cells. Substrate mechanical properties include elasticity, tension, adhesion, and myosin-based contractile mechanisms. Inhibitors can be introduced to further regulate differentiation.

Polymer substrates including adhesion layers for activating the surface of the substrate are provided, thereby allowing the substrate to react with organic, inorganic, metallic and / or organometallic materials. The surface of the polymer substrate is coated with a metal oxide layer that is subjected to conditions adequate to form an oxide adhesion layer. Combining deposition techniques for formation of functionalized polymer surfaces with photolithographic techniques enables spatial control of RGD presentation at the polymer surfaces are achieved with sub-cellular resolution. Surface patterning enables control of cell adhesion location at the surface of the polymer and influences cell shape. Metallization of polymers as described herein provides a means to prepare metal-based electrical circuitry on a variety of flexible substrates.

Multi-dimensional symbology codes that use plural characteristic features encoded in a data cell and related methods. Such methods include methods of encoding, methods of creating and methods of reading multi-dimensional symbology codes that use such plural characteristic features. The features, for example, include colors, grey scale levels, cell shape, patterns within a cell or any grouping discernable by an area array camera or similar device.

A method for manufacture of application specific solar cells includes providing and processing custom design information to determine at least a cell size and a cell shape. The method includes providing a transparent substrate having a back surface region, a front surface region, and one or more grid-line regions overlying the front side surface region. The one or more grid regions provide one or more unit cells having the cell size and the cell shape. The method further includes forming a layered structure including photovoltaic materials overlying the front surface region. Additionally, the method includes aligning a laser beam from the back surface region to illuminate a first region within the one or more grid-line regions, subjecting a first portion of the layered structure overlying the first region to the laser beam to separate the first portion of the layered structure from the first region, and scanning the laser beam along the one or more grid-line regions to cause formation of one or more unit cells having the cell size and cell shape. The method further includes transferring the one or more unit cells.

A method is disclosed for producing a 2D collimator element for a radiation detector, in which crossing webs made of a radiation-absorbing material are formed, layer-by-layer, by way of a rapid manufacturing technique. In at least one embodiment, the webs are aligned along a [phi]- and a z-direction and form a cell-shaped structure with laterally enclosed radiation channels, at least in the inner region of the 2D collimator element. In at least one embodiment, the invention moreover relates to a 2D collimator element for a radiation detector that has such a layered construction. This allows the provision of a very precise and rigid collimator arrangement which, at the same time, has a high collimation effect.

The present invention provides a series of methods, compositions, and articles for altering a property of a surface (for example, the cytophilicity and / or the hydrophilicity), by exposing at least a portion of the surface to a non-chemical, force-creating field and / or force, such as an electric field. The field / force may be created by any suitable technique. For instance, the field can be created by applying a voltage across the surface, by electrical induction, etc. In certain embodiments, the surface includes molecules attached thereto that can be detached when exposed to non-chemical, force-creating fields and / or forces, thereby altering the chemical composition of at least a portion of the surface. In one set of embodiments, the molecules attached to the surface may include molecules forming a self-assembled monolayer on the surface. In some embodiments, the molecules attached to the surface may include thiol moieties (e.g., as in an alkanethiol), by which the molecule can become attached to the surface. In certain cases, the molecules may be terminated at the unattached end with one or more hydrophilic groups, for example, unmodified ethylene glycol moieties. In some cases, the molecules attached to the surface may include one or more moieties that can bind to various entities such as proteins, peptides, nucleic acids, drugs, cells, etc. In certain embodiments, the techniques are used to enable novel assays for cell motility and / or spreading and screening tests for determining drugs and / or treatments effective in increasing or decreasing cell shape changes and / or motility on surfaces.

Several inventions are disclosed. A cell architecture using hexagonal shaped cells is disclosed. The architecture is not limited to hexagonal shaped cells. Cells may be defined by clusters of two or more hexagons, by triangles, by parallelograms, and by other polygons enabling a variety of cell shapes to be accommodated. Polydirectional non-orthogonal three layer metal routing is disclosed. The architecture may be combined with the tri-directional routing for a particularly advantageous design. In the tri-directional routing arraingement, electrical conductors for interconnecting terminals of microelectronic cells of an integrated circuit preferrably extend in three directions that are angularly displaced from each other by 60 DEG . The conductors that extend in the three directions are preferrably formed in three different layers. A method of minimizing wire length in a semiconductor device is disclosed. A method of minimizing intermetal capacitance in a semiconductor device is disclosed. A novel device called a "tri-ister" is disclosed. Triangular devices are disclosed, including triangular NAND gates, triangular AND gates, and triangular OR gates. A triangular op amp and triode are disclosed. A triangular sense amplifier is disclosed. A DRAM memory array and an SRAM memory array, based upon triangular or parallelogram shaped cells, are disclosed, including a method of interconnecting such arrays. A programmable variable drive transistor is disclosed. CAD algorithms and methods are disclosed for designing and making semiconductor devices, which are particularly applicable to the disclosed architecture and tri-directional three metal layer routing.

Several inventions are disclosed. A cell architecture using hexagonal shaped cells is disclosed. The architecture is not limited to hexagonal shaped cells. Cells may be defined by clusters of two or more hexagons, by triangles, by parallelograms, and by other polygons enabling a variety of cell shapes to be accommodated. Polydirectional non-orthogonal three layer metal routing is disclosed. The architecture may be combined with the tri-directional routing for a particularly advantageous design. In the tri-directional routing arraingement, electrical conductors for interconnecting terminals of microelectronic cells of an integrated circuit preferrably extend in three directions that are angularly displaced from each other by 60°. The conductors that extend in the three directions are preferrably formed in three different layers. A method of minimizing wire length in a semiconductor device is disclosed. A method of minimizing intermetal capacitance in a semiconductor device is disclosed. A novel device called a "tri-ister" is disclosed. Triangular devices are disclosed, including triangular NAND gates, triangular AND gates, and triangular OR gates. A triangular op amp and triode are disclosed. A triangular sense amplifier is disclosed. A DRAM memory array and an SRAM memory array, based upon triangular or parallelogram shaped cells, are disclosed, including a method of interconnecting such arrays. A programmable variable drive transistor is disclosed. CAD algorithms and methods are disclosed for designing and making semiconductor devices, which are particularly applicable to the disclosed architecture and tri-directional three metal layer routing.

The present invention relates to a method and an apparatus for sorting cells. The apparatus for determining the mechanical properties of cells comprises: —a microfluidic channel having an inlet and an outlet, the channel being configured to let a fluid containing cells pass therethrough, —a means for introducing a fluid containing cells into the channel so as to establish a flow of the fluid within the channel, —a cell shape measurement device arranged to obtain information of a deformed shape of a cell deformed due to the flow pattern created by the interaction of the fluid flow with the channel, and —an analysis means arranged to use data from the cell shape measurement device to obtain mechanical properties of the cells.

The invention discloses a stool sample preservation liquid, a preparation method and application thereof. Specifically, the stool sample preservation liquid contains: 45 vol%-60 vol% of a fixing agent; 0.1 mass%-15 mass% of a fixing agent adjuvant; 0.01 mass%-1.5 mass% of an anticoagulant; 10 vol%-15 vol% of a buffer solution; 0.01 mass%-1 mass% of an ionic strength maintenance agent; 0.01 vol%-0.5 vol% of a nonionic detergent; and the balance water. The stool sample preservation liquid provided by the invention has the characteristics of easy preparation and low cost, can preserve stool samples at room temperature, also can effectively inhibit DNA degradation and cell damage of stool samples, maintain cell shape, and can preserve samples for a long time, and the preserved samples have high qualification rate during reutilization.

Provided is a cell concentration and purification device, having: a function of continuously concentrating cells; a function of then subsequently disposing the cells continuously in a specific region of a channel; a function of simultaneously recognizing, based on an image, the shape and fluorescence emission of each single cell; and a function of recognizing the cells and then separating and purifying the same based on the data relating to the shape and fluorescence emission thereof.

The invention discloses an arid area desert sand fixation method. The method includes the steps that firstly, parallel strip-shaped sand barriers which are in a cell shape and have the side length ranging from 1 m to 2 m or parallel strip-shaped sand barriers with the interval ranging from 1 m to 2 m are pressed on a drought dessert area; secondly, wide-line densely-planted shrubbery strips are planted in the sand barriers mentioned in the first step, wherein due to the row spacing of the shrubbery strips, the ventilation coefficient of the shrubbery strips ranges from 0.3 to 0.45 after the shrubbery strips grow into forests, and the row spacing is 10 times to 20 times of the average height of the shrubbery strips after the shrubbery strips grow into the forests. The technology of conducting comprehensive sand fixation by combining the cell-shaped or the strip-shaped sand barriers with wide-line densely-planted forestation is adopted, and therefore the number of trees in the unit area is reduced, survival and normal growth of the trees can be ensured even in places where rainfall capacity is small, and the wind prevention and sand fixation effect can be given into full play for a long time to the maximum extent.

A medical image processor and a storage medium are shown. According to one implementation, the medical image processor includes the following. An input unit is used to input a cell shape image and a fluorescent image showing expression of a specific protein. A cell nucleus extracting unit extracts a cell nucleus. A fluorescent bright point extracting unit extracts a fluorescent bright point. A region estimating unit sets a predetermined region. When the set region does not overlap with another, it is estimated to include one cell. When a plurality of the set regions overlap, it is estimated to include a plurality of cells. A feature amount calculating unit calculates a feature amount. A determining unit determines whether each estimated cell region is cancer and determines an expression status in the region based on the calculated feature amount. An output unit outputs a determination result.

A medical image processor and storage medium are shown. According to one implementation, a medical image processor includes an input unit, an operation unit, a cell nucleus extracting unit, a fluorescent bright point extracting unit, a feature amount calculating unit, and an output unit. The input unit is used to input a cell shape image showing a shape of a cell and a fluorescent image showing expression of a specific protein as a fluorescent bright point. The operation unit is used to specify an analysis target region. The cell nucleus extracting unit extracts a region of a cell nucleus. The fluorescent bright point extracting unit extracts a fluorescent bright point. The feature amount calculating unit calculates a feature amount showing an expression amount of the specific protein. The output unit outputs the calculated feature amount.

The invention provides a microwave aging treatment method for cobalt-based rare earth permanent magnetic materials. Cobalt-based rare earth permanent magnetic material sintered blanks prepared by a powder metallurgy method are treated in a second-stage artificial aging or multi-stage artificial aging manner after the heating and the heat preservation in a microwave manner; by utilizing the high-frequency electromagnetic field of microwaves, on one hand, the electron spin magnetic moment orientation of 3d casing layers of transition metals in alloys is affected, the bonding energy between the transition metals and rare earth metals is weakened, the nucleation potential barriers of new Sm2Co17R phrases and SmCo5 phrases are reduced, nanocrystalline particles containing the Sm2Co17R phrases and the SmCo5 phrases are beneficial to form, and high saturation magnetization intensity and high mechanical property can be obtained; on the other hand, the microwaves can be converted into the diffused energy of atoms, the diffused speed of the atoms is increased, the sintering progress is accelerated, and the cell-shaped structures are refined. For the rare earth permanent magnetic materials treated by the method, the cell-shaped structures can be small and uniform. The method can be applied to prepare rare earth permanent magnetic materials which contain Sm (samarium), Co (cobalt), Fe (ferrum), Cu (copper), Zr (zirconium) or Ti (titanium) and have good mechanical property and high mechanical property, so that the method is suitable for industrialized application.

A non-aqueous electrolyte cell is provided having improved cell characteristics and which maintains a cell shape encapsulated in a laminate film even when overdischarged to a cell voltage of 0 V. The cell includes an anode, an electrolyte, and a cathode containing a compound having the formula LixFe1-yMyPO4, wherein 0.05≦x≦1.2 and 0≦y≦0.8, and wherein M is at least one element selected from the group consisting of Mn, Cr, Co, Cu, Ni, V, Mo, Ti, Zn, Al, Ga, Mg, B and Nb. Exposed portions of an anode current collector and a cathode current collector prevent internal shorting of the cell.

We describe an improved method for generating sizable numbers of mature dendritic cells from nonproliferating progenitors in human blood. The first step or “priming” phase is a culture of T cell depleted mononuclear cells in medium supplemented with GM-CSF and IL-4 to produce immature dendritic cells. The second step or “differentiation” phase requires the exposure to dendritic cell maturation factor such as monocyte conditioned medium. Using this two-step approach, substantial yields are obtained. The dendritic cells derive from this method have all the features of mature cells. They include a stellate cell shape, nonadherence to plastic, and very strong T cell stimulatory activity. The mature dendritic cells produced according to this invention are useful for activating T cells.

The present disclosure is directed, among other things, to automated systems and methods for analyzing, storing, and / or retrieving information associated with biological objects including lymphocytes. In some embodiments, a shape metric is derived for each detected and segmented lymphocyte and the shape metric is stored along with other relevant data.

A radio antenna of a radio base station is a directional antenna. The antenna searches for a peripheral radio base station by changing the directivity of the antenna. An operating channel and electric field intensity of the other base station are acquired by the searching and then stored as positional information. The operating channel of the base station, the directivity of the antenna, and a radio wave intensity communication area are set according to the acquired positional information. Further, the positional information is transmitted and received to and from the other base station to set the base station. When the base station was moved or when external noise occurred abruptly, channel change and change of a cell shape of the directional antenna are carried out. Consequently, interference between the base stations can be minimized and optimum setting of the channel and communicatable area can be realized.

The invention relates to a method for quantificationally characterizing cell shape features of flue-cured tobacco leaves by utilizing Photoshop software, which is characterized by comprising the following steps of: obtaining a surface cell feature image of the preliminarily-flue-cured tobacco leaves through a scanning electron microscope, accurately selecting cells by utilizing a magnetic lasso, a matte, a paintbrush, an eraser and other tools, respectively and quantificationally obtaining the cell circumference and the cell area by using a unit pixel length*number of pixels and pixel percentage*image area method, calculating shape feature parameters through taking the circumference and the area as variables by utilizing a formula to provide a method for objectively evaluating the cell development situations of the tobacco leaves and researching the quality features of the tobacco leaves from the microscopic field. Measurement results of a plurality of cells randomly selected from different places of origin show that the method is high in accuracy and high in fitting degree of the calculated cell shape feature parameters with software-defined roundness values (R2 is equal to 0.98-0.99), and meanwhile, the cell shape features (quality features) of the tobacco leaves from the different places of origin can be better distinguished.

The invention discloses a fresh water algae rough classification and counting method based on lensless holographic imaging. Binaryzation processing of a fresh water algae holographic image, which is acquired by using a lensless holographic imaging device, is carried out, and a ratio of an area of a whole image occupied by all of cells is calculated. Simple classification and simple counting of cell images having dispersed cells and less cells are carried out by using a method based on a cell shape characteristic. The simple classification and the simple counting of the cell images having the concentrated cells and a lot of cells are carried out by using a cross-correlation matching method based on normalization. The rough classification and the rough counting of the cells in the fresh water algae holographic image are carried out in a targeted and accurate manner, and different solutions are provided by aiming at the cell images having different cell distribution ways and different cell numbers, and therefore the better effects of the rough classification and the counting are realized; and at the same time, realization complexity is low, image processing time is short, and final rough classification and counting results are ideal.

The invention discloses an ovarian cancer tissue 3D cultivation method. The method includes the steps that matrigel is dripped into a pore plate, and standing is conducted at an indoor temperature or in a CO2 cultivation box so that the gel can be solidified; a tumor tissue block submerged in a cultivation solution is moved onto the solidified matrigel, then matrigel is dripped onto the tumor tissue block and the gel is solidified in the same way; a cultivation solution is added for cultivation for 1-3 days; the tumor tissue block is taken out and fixed. Chemotherapeutics can be added during cultivation, the tissue block is fixed after cultivation, the cell shape is observed after dyeing, and the nucleus malformation rate is calculated. By means of the established cultivation method and detection indexes, the pharmacological effects and the function characteristics of anti-tumor drugs can be evaluated more quickly and accurately, the technical defects of cell 2D cultivation and animal experimental evaluation can be overcome, and it is hopeful that the research and development of innovative anti-cancer drugs in China and the precision therapeutic process can be promoted.

A method and apparatus for transmitting a cell shaping / un-shaping indication in a wireless communication system is provided. A first eNodeB (eNB) transmits a cell shaping / un-shaping indication which indicates cell shaping / un-shaping of a cell, managed by the first eNB, in an active antenna system (AAS) to a second eNB. The cell shaping means that main coverage of the cell is maintained unchanged but an edge of the cell can be adapted to load demand. The cell un-shaping means that coverage of the cell goes back to original coverage.

Disclosed are an ultrasound probe and an ultrasound imaging device capable of reducing extraneous response that is caused by higher vibrational modes and that occurs when the cell shape of a capacitive micro-machined ultrasonic transducer is anisotropic. A representative aspect ratio (l / w) serving as a ratio of the longer length (l) to the shorter length (w) of a vibrating film included in the capacitive micro-machined ultrasonic transducer is set such that dips more than or equal to 6 dB are not formed in the transmission / reception band width of the probe. Alternatively, the representative aspect ratio is set such that six or more vibrational modes, each having an odd number of loops and values obtained by dividing the frequencies of the vibrational modes by the frequency of the fundamental mode being two or less, exist.

A stent for use with a prosthetic heart valve for replacement of a native valve includes an expandable stent body having a collapsed configuration and an expanded configuration, with an annulus section at an inflow end of the stent body and an aortic section at an outflow end. A plurality of commissure attachment features are positioned circumferentially around the stent body. A distal edge of the annulus section is generally parabolic and extends from one of the commissure attachment features to an adjacent one of the commissure attachment features, with the middle of the parabola being closest to the inflow end of the stent body.