A novel resin sealant is prepared from the following raw materials in parts by weight: 20-40 parts of epoxy resin, 30-50 parts of cis-1,4-polybutadiene rubber, 25-35 parts of thermoplastic synthetic resin, 3-8 parts of diatomite, 15-20 parts of polyisobutylene, 4-8 parts of xylene solution of raw rubber, 8-14 parts of xylene, 6-10 parts of ebonite, 9-18 parts of dibutyl phthalate, 11-16 parts of asbestos powder, 10-15 parts of nanometer calcium carbonate, 7-14 parts of m-phenylenediamine, 3-6 parts of barium sulfate, 11-17 parts of rutile titanium dioxide and 6-12 parts of a phosphate fire retardant. The novel resin sealant is good in sealing property, resistant to water seepage, airtight, good in weatherability, good in low-temperature crack resistance, excellent in heat-insulation shock-proof performances, beneficial for construction and installation, and good in fireproof effect.