33 results about "Stomach ache" patented technology

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to stasis-removing and pain-relieving pills and a quality detection method thereof. The stasis-removing and pain-relieving pill is prepared by taking radix paeoniae alba, rhizoma corydalis, radix paeoniae rubra, angelica sinensis, ligusticum wallichii, rhizoma cyperi, rhizoma zingiberis, fennel and astragalus membranaceus as raw materials and taking 10% starch slurry as an adhesive. The quality detection method of the stasis-removing and pain-relieving pill comprises general inspection, microscopic identification and thin-layer chromatography identification. And high performance liquid chromatography content determination. According to the present invention, by researching the preparation process and the quality standard of the stasis removing and pain relieving pill, the new thought and the new method are provided for the development of the traditional Chinese medicine preparation, the excellent choice is hopefully provided for the common gynecologic symptoms such as irregular menstruation, dysmenorrhea, postpartum blood stasis abdominal pain and the like, and the pain caused by the illness is relieved.

The invention discloses an external application medicine formula for acute pancreatitis, and belongs to the field of traditional Chinese medicine preparation formulas, and the external application medicine formula for acute pancreatitis is prepared from the following raw materials in parts by weight: 1-2 parts of honeysuckle, 1-2 parts of wild chrysanthemum flower, 1-2 parts of dandelion, 1-2 parts of herba violae, 1 part of scutellaria baicalensis, 1 part of coptis chinensis, 1 part of raw rhubarb, 1 part of raw liquorice, 1 part of radix paeoniae rubra and 1 part of mangnolia officinalis. The traditional Chinese medicine composition can effectively reduce peripancreatic exudation and promote gastrointestinal motility, so that the symptoms of abdominal distension and abdominal pain of a patient are relieved, meanwhile, pancreatic microcirculation can be improved, disease recovery is facilitated, the preparation process is simple and easy to understand, complex equipment is not needed, and the production cost is greatly reduced.

The invention discloses application of a pain and diarrhea prescription to regulation and control of a BLP + macrophage subgroup to treat IBS-D. The pain and diarrhea prescription contains a liver soothing component (6-10 parts of pericarpium citri reticulatae and 6-10 parts of radix saposhnikoviae) and a spleen tonifying component (10-15 parts of rhizoma atractylodis macrocephalae and 10-15 parts of radix paeoniae alba) or a combination of the liver soothing component and the spleen tonifying component according to the ratio of 1: (1-2). By promoting the expression of anti-inflammatory cytokines IL-10 and TGF-beta, inhibiting the expression of pro-inflammatory cytokines IL-6 and TNF-alpha, activating an AMPK signal channel, inhibiting an NF-kappa B signal channel and promoting the expression of colonic mucosal barrier indexes ZO1 and OCLN, a colonic mucosal barrier is repaired, and the symptoms of IBS-D abdominal pain and diarrhea are relieved. The invention also provides a pharmaceutical composition containing the key active component, and the dosage forms comprise an aqueous solution, a tablet and the like. The traditional Chinese medicine composition solves the problems of large toxic and side effects, poor compliance and unknown mechanism in the existing IBS-D treatment, is definite and safe in curative effect, and has important clinical value and scientific significance.

The invention discloses a traditional Chinese medicine composition, a decoction, granules and application thereof. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 5-15 parts of radix scutellariae, 3-7 parts of rhizoma coptidis, 5-15 parts of radix puerariae, 5-15 parts of radix paeoniae alba, 8-16 parts of radix angelicae sinensis, 5-15 parts of raw radix sanguisorbae, 10-20 parts of herba portulacae, 4-8 parts of radix aucklandiae and 3-7 parts of honey-fried licorice root. The traditional Chinese medicine composition not only can directly act on the cause of damp-heat, but also can comprehensively cover enteritis symptoms such as abdominal pain, diarrhea, tenesmus, bloody purulent stool and the like, can relieve the disadvantage that the stomach is injured by bitter and cold medicines, is strong in clinical pertinence, and is suitable for enteritis caused by ulcerative colitis, bacteria, viruses, radioactivity and the like; the traditional Chinese medicine composition can also be matched with probiotics to treat western medicine chronic diarrhea and traditional Chinese medicine diarrhea. Therefore, the traditional Chinese medicine composition or the decoction and the granules thereof have the prospect of being developed into the medicine for treating enteritis or the prospect of being developed into the medicine for treating western medicine chronic diarrhea and traditional Chinese medicine diarrhea in cooperation with the probiotics.

The invention relates to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating postoperative digestive tract reaction of malignant tumors, a preparation and application. The traditional Chinese medicine composition comprises the following active ingredient raw materials in parts by weight: 10-20 parts of fried codonopsis pilosula, 10-20 parts of fried bighead atractylodes rhizome, 10-20 parts of poria cocos, 1-10 parts of liquorice, 10-20 parts of fried endothelium corneum gigeriae galli, 15-25 parts of fried malt, 25-35 parts of adina rubella hance root, 25-35 parts of wild grape root, 15-25 parts of Chinese actinidia root and 15-25 parts of coix seed. The traditional Chinese medicine composition and the preparation can effectively treat patients with malignant tumor postoperative digestive tract reaction, effectively improve symptoms of abdominal distension, stomachache, nausea, vomiting, diarrhea, constipation, anorexia, sour regurgitation, oral cavity / throat dryness and the like of the patients, improve the life quality of the patients and have good safety.

The invention discloses a compound composition based on a Gegen Qinlian decoction, and belongs to the technical field of medicines. The active ingredients of the compound composition comprise puerarin, baicalin, berberine, glycyrrhizic acid and paeoniflorin, and the compound composition comprises pharmaceutically acceptable auxiliary materials. The daily dose of the compound composition is prepared from the following components in parts by mass: 50 to 300 parts of puerarin, 50 to 800 parts of baicalin, 50 to 800 parts of berberine, 25 to 300 parts of glycyrrhizic acid and 30 to 150 parts of paeoniflorin. The compound composition is composed of five clear active components, and through accurate control and standardized quality control of the active components, the stability of the product quality and the reliability of the curative effect are fundamentally ensured. Network pharmacological analysis and animal experiment results show that the composition has antipyretic, anti-inflammatory and analgesic effects, is matched with the traditional Chinese medicine effects of relieving muscles and relieving exterior syndrome, clearing away heat and toxic materials, and promoting diuresis and stopping dysentery, and is suitable for treating stomachache, headache and body pain.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine intestinal administration preparation for treating UC and a preparation method. The traditional Chinese medicine intestinal administration preparation for treating UC comprises the following raw material medicines in parts by weight: 20-50 parts of rhizoma coptidis, 20-50 parts of cortex phellodendri, 20-50 parts of radix sanguisorbae, 20-50 parts of radix paeoniae alba, 20-50 parts of rhizoma bletillae, 10-40 parts of radix sophorae flavescentis and 10-40 parts of liquorice root. The composition is prepared by combining various medicines, has the effects of eliminating dampness and heat, cooling blood, stopping bleeding, astringing sores and promoting tissue regeneration, and the seven medicines are used together, so that the treatment effect is improved, a synergistic effect is achieved, and the composition is good in effect and free of toxic and side effects when being used for clinical treatment of UC for a long time; the preparation has strong heat-clearing and bleeding-stopping effects, can quickly relieve symptoms such as stomachache, tenesmus and hematochezia caused by UC, and effectively promotes intestinal mucosa healing.

The traditional Chinese medicine composition disclosed by the invention adopts a method of warming yang and relieving exterior syndrome to achieve the effects of freeing lung and inducing diuresis, tonifying spleen and warming kidney, and strengthening defensive qi and diminishing swelling, and is prepared to be used for treating the immune-related glomerular diseases, especially membranous nephropathy and minimal lesion nephropathy. The traditional Chinese medicine composition is a pure traditional Chinese medicine preparation, clinical observation and in-vivo and in-vitro basic tests show that the prescription can remarkably improve edema, massive proteinuria, hypoproteinemia and the like, meanwhile, compared with the prior art, the traditional Chinese medicine composition has a better effect on symptoms such as stomachache and diarrhea, has an anti-inflammatory effect and does not have obvious side effects in clinical application. The traditional Chinese medicine composition has an excellent effect on patients suffering from membranous nephropathy and minimal lesion nephropathy caused by syndrome differentiation of spleen-kidney yang deficiency, internal rheumatism and water-fluid overflowing.

The invention discloses a method for evaluating the analgesic effect of angelica sinensis stomachache dropping pills, belongs to the technical field of efficacy evaluation, and aims to solve the problem that no scientific method is provided for efficacy verification of dysmenorrhea traditional Chinese medicine preparations in the formula of angelica sinensis. The method comprises the steps of experimental mouse selection, acetic acid body twisting model test, hot plate pain model test and xylene inflammation model test. Selecting an experimental rat, and testing the primary dysmenorrhea model constructed by estradiol and oxytocin. The method comprises the following steps: constructing an analgesic effect evaluation model, and verifying analgesic and anti-inflammatory effects of angelica sinensis stomachache relieving; pharmacodynamic mechanism analysis is further carried out on the angelica sinensis stomachache dropping pill for simulating primary dysmenorrhea, it is revealed that the content of serum E2, IL-6, PROG, beta-EP and TNF-alpha of primary dysmenorrhea model rats treated by the angelica sinensis stomachache dropping pill has an adjusting effect, the effect of relieving dysmenorrhea can be achieved, the inflammation effect can be relieved by inhibiting NF-kappa B and MAPK channels, and the pain behavior can be relieved.

The invention relates to the field of medicines, in particular to a traditional Chinese medicine composition for treating pancreatitis and a preparation process thereof. The traditional Chinese medicine composition is prepared from more than 30 traditional Chinese medicines such as rheum officinale, codonopsis pilosula, astragalus membranaceus, cape jasmine, radix curcumae, polygonum cuspidatum and rhodiola rosea. Animal experiments prove that the traditional Chinese medicine composition disclosed by the invention can be used for remarkably reducing the ascites amount of rats with severe acute pancreatitis and expression of inflammatory factors such as amylase, serum lipase, IL-1beta and IL-18, and remarkably reducing the incidence rate of pancreatic pseudocyst and abscess. Observed from clinical curative effects, the traditional Chinese medicine composition disclosed by the invention has a relatively good treatment effect on severe acute pancreatitis, acute light pancreatitis and chronic pancreatitis, the symptoms of abdominal pain, diarrhea, nausea and abdominal distension of patients in the treatment process are obviously relieved, and the symptoms are obviously advanced and improved through gastrointestinal tract eating. And further popularization and application are facilitated.

The aloe particles are prepared from the following raw materials in parts by weight: 50 to 100 parts of fructus amomi rotundus, 100 to 150 parts of indigo naturalis, 100 to 150 parts of amber and 120 to 170 parts of aloe. According to the aloe particles capable of relaxing bowels and the preparation method, on the basis of a classic heat-clearing and bowels-relaxing formula composed of indigo naturalis, amber and aloe, cardamom is creatively introduced as a key adjuvant drug, and a wonderful compatibility system of monarch, minister, assistant and guide is constructed; the aloe is used as a monarch for purgation and bowel relaxing, the indigo naturalis is used as a minister for strengthening the effect of clearing heat, the amber is used for soothing the nerves, promoting blood circulation and regulating the drug property, and the cardamom has the effects of warming the middle warmer and promoting the circulation of qi, so that on one hand, the spleen yang is boosted, the transportation and transformation of the spleen and the stomach are promoted, the intestinal propulsive force is enhanced from the root of qi stagnation, and the qi is promoted to relax bowel; on the other hand, the cold and cool properties of aloe and indigo naturalis are precisely restricted, the core pain points of adverse reactions such as stomachache and weakness after diarrhea caused by the fact that traditional preparations are prone to damage spleen and stomach yang qi are thoroughly solved, and'tonification and purgation 'and'warm and cold'are achieved.

The invention discloses a processing method of rhubarb traditional Chinese medicine decoction pieces, and relates to the technical field of traditional Chinese medicine processing, and the processing method specifically comprises the following steps: S1, slicing rhubarb to obtain rhubarb slices; sealing and moistening the rhubarb tablets in the medicinal liquor mixed liquor until the medicinal liquor mixed liquor is completely absorbed; s2, steaming the rhubarb slices obtained in the step S1, then taking out the rhubarb slices, and airing the rhubarb slices until the water content is 13% or below; s3, sterilizing the rhubarb slices in the step S2, then adding a bacterial solution, uniformly mixing, and carrying out fermentation culture; and S4, steaming the fermented rhubarb slices in the step S3, taking out the steamed rhubarb slices, and airing the steamed rhubarb slices until the water content is 13% or below. The method is easy and convenient to operate, the bitter cold property of the rheum officinale can be effectively improved, the content of combined anthraquinone is reduced, the content of free anthraquinone is increased, and adverse reactions such as stomachache and diarrhea are reduced.

The invention provides a critical patient nursing liquid food taking device which comprises a feeding cylinder, a partition plate and a driving assembly, and the interior of the feeding cylinder is hollow to form a cavity; the partition plate is arranged in the cavity in the axial direction and divides the cavity into a stirring cavity and a feeding cavity. A through groove is formed in the end face of the partition plate, a conveying pipe is installed in the through groove, and a one-way conduction component is arranged on the conveying pipe. The driving assembly is arranged in the feeding cavity, and the driving end of the driving assembly extends to the outer side of the feeding cylinder; the driving assembly is used for enabling the feeding cavity to generate negative pressure, so that the liquid food in the stirring cavity enters the feeding cavity through the one-way conduction component. The amount of air inhaled by a patient in the feeding process is greatly reduced, the occurrence rate of uncomfortable symptoms such as gastrointestinal flatulence and stomachache can be remarkably reduced, meanwhile, the aspiration pneumonia risk caused by the fact that air enters an airway by mistake along with liquid food is effectively avoided, and the safety and comfort of liquid food feeding are improved.

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for improving gastrointestinal motility disorder and a preparation method thereof, and the traditional Chinese medicine composition is prepared from the following raw materials: fried malt, fried rice sprout, poria cocos, fructus amomi and liquorice. The traditional Chinese medicine composition disclosed by the invention can improve clinical symptoms such as postprandial fullness, early satiety, epigastric pain and epigastric discomfort caused by gastrointestinal motility disorder, epigastric burning feeling and epigastric spasmodic pain; insufficient gastric motility caused by gastrointestinal motility disorder is relieved, and nausea, vomiting, ozostomia, sour regurgitation or bitter regurgitation in the mouth are improved; the traditional Chinese medicine is used for treating weakness of spleen and stomach, and improving the symptoms of poor appetite, anorexia, fatigue, intolerance of cold, cold limbs and sweet excrement caused by stomach cold dull pain, stomach cold distention and fullness, warm and press liking.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition with kidney tonifying and bowel relaxing functions and a preparation method, a preparation and application thereof. The traditional Chinese medicine composition comprises the following components: wine-processed cistanche, angelica sinensis, cooked rhubarb, semen cassiae, achyranthes bidentata, radix paeoniae alba, pericarpium citri reticulatae, rhizoma alismatis, fructus aurantii and rhizoma cimicifugae. The traditional Chinese medicine composition provided by the invention is mainly used for warming the kidney, boosting essence and relaxing bowel. The traditional Chinese medicine is used for treating dry stool, constipation due to intestinal dryness, clear and long urine, soreness and weakness of waist and knees, general weakness, stomachache, abdominal distension, blood deficiency and sallow yellowness, insomnia, headache and dizziness, spontaneous perspiration and inappetence caused by kidney deficiency and body fluid deficiency; the traditional Chinese medicine is used for treating irritable bowel syndrome and menstrual disorder.

The present application provides a kind of instant enema health coffee containing probiotics and its processing method, which is composed of the following raw materials in mass percentage: low-acid arabica coffee base 40-50%, the coffee base is 160-170 ℃, 10-15 min shallow roasting, roasting degree 40-50%; Composite probiotics 5-8%, the composite probiotics is bifidobacterium (CGMCC1.396), lactobacillus plantarum (CGMCC1.557), lactobacillus rhamnosus (CGMCC1.3724) is compounded according to 2:1:1, total viable count ≥10 10 CFU / g, and is treated by microcapsule embedding; through shallow roasting control coffee irritant ingredient content, cooperate with the buffering effect of pH regulator and licorice extract, make enema liquid pH stable at 5.5-6.5, highly adapt to intestinal environment, avoid mucosa damage, no abdominal pain, diarrhea and other discomfort, adapt to long-term intestinal health needs.

The invention discloses a herbal formula with the effects of regulating menstruation, relieving pain, warming ovary, warming uterus and dredging qi and blood, and particularly relates to the technical field of traditional Chinese medicine conditioning, and the herbal formula comprises special decoction prescriptions for the premenstrual period, the menstruation period and the post-menstrual period and corresponding preparation processes of the decoction prescriptions. The traditional Chinese medicine composition comprises the following components by weight: 5-7g of loofah sponge, 4-6g of liquidambar formosana hance, 5-7g of rose, 7-9g of fried hawthorn, 4-6g of pericarpium citri reticulatae, 9-11g of poria cocos and 20-30g of red dates. The formula strictly adapts to the physiological characteristics and common discomfort of the menstrual cycle including the premenstrual period, the menstrual period and the post-menstrual period, staged precise intervention is achieved, the limitation of a single soup formula is broken through, meanwhile, dual repair of ovary maintenance and qi and blood nourishing is achieved, and the curative effect is good. Periodic conditioning can effectively relieve common menstrual period problems such as premenstrual swelling pain, menstrual period abdominal pain and latter menstrual period weakness, and long-term use of the traditional Chinese medicine is helpful for improving the menstrual cycle rule, so that female reproductive health is maintained from the source.

The invention discloses a pepper and brown sugar composition with immediate cold dispelling and abdomen warming functions and a preparation method thereof, and belongs to the technical field of functional foods. The composition is prepared from the following raw materials in percentage by weight: 85-95% of brown sugar, 5-15% of pepper and water which accounts for 15-35% of the total weight of the brown sugar and the pepper. The preparation method comprises the following steps: mixing the brown sugar, the pepper and the water in proportion, boiling at 105-130 DEG C, and frying to completely evaporate water, thereby finally forming a sand-like material. The core of the invention lies in that the bioavailability of functional components is remarkably improved through scientific compatibility of greatly increasing the proportion of pepper to 5-15% and a unique'boiling-stir-frying 'process. The obtained product can be rapidly dissolved and release effective components after being brewed with hot water, discomfort such as dysmenorrhea, stomach cold and stomachache due to cold can be rapidly and instantly relieved, and the problem that a traditional product takes effect slowly is solved. The composition can be further processed into various forms such as instant drinking blocks, granules, tablet candies, liquid beverages, external products and the like, and is wide in application.

This invention discloses the application of porcine bile acid components in the preparation of drugs for treating irritable bowel syndrome (IBS-D). The study found that the content of porcine bile acid components in the peripheral feces of IBS-D patients treated with traditional Chinese medicine was significantly increased. Furthermore, compared with a healthy control group, the content of porcine bile acid components in the peripheral fecal samples of IBS-D patients was significantly reduced. Further research revealed that porcine deoxycholic acid and natural traditional Chinese medicine porcine bile powder can significantly improve diarrhea and abdominal pain symptoms in TNBS-induced mice by inhibiting tryptophan hydroxylase 1 activity and reducing peripheral serotonin levels. This invention suggests the application value of porcine bile acid components in the treatment of IBS-D.

The invention provides a traditional Chinese medicine composition for treating diarrhea-type irritable bowel syndrome. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials: radix paeoniae alba, hypericum perforatum, codonopsis pilosula, rhizoma atractylodis macrocephalae, semen cuscutae, fructus evodiae, rhizoma zingiberis, fructus amomi rotundus, schisandra chinensis and radix curcumae. The traditional Chinese medicine composition has the effects of warming kidney and strengthening spleen, soothing liver-qi stagnation and relieving diarrhea with astringents. The traditional Chinese medicine composition disclosed by the invention has an outstanding clinical effect on treating the diarrhea-type irritable bowel syndrome, and particularly has an obvious curative effect on patients with abdominal distension, abdominal pain, diarrhea, belching, dysphoria, dull pain, bitter mouth, light tongue, white and smooth tongue coating and deep and thin pulse caused by spleen-kidney yang deficiency, liver-qi stagnation and intestinal dysfunction.

The invention discloses a sectional type gastric bypass stent conveying and releasing system, and relates to the technical field of medical instruments. The sectional type gastric bypass stent conveying and releasing system comprises a sectional type stent and a conveying and releasing mechanism, the sectional bracket comprises an upper bracket, a lower bracket, a connecting rope and a membrane tube, the upper bracket and the lower bracket are connected through the connecting rope, and one end, far away from the upper bracket, of the lower bracket is connected with the membrane tube; the lower support and the membrane pipe are both contained in a containing pipe of the conveying and releasing mechanism, the membrane pipe is connected with the releasing small ball, the lower support makes contact with the support pushing block, the connecting rope is led out of the rope passing groove, and the upper support is contained in a gap between a conveying pipe of the conveying and releasing mechanism and an outer sleeve. The sectional stent provided by the invention reduces the incidence rate of gastrointestinal tract events (vomiting, nausea, stomachache and the like) and stent displacement, reduces the occurrence rate of gastric retention or obstruction, and is not easy to form pressure ulcer. The sectional type support and the conveying and releasing mechanism are high in matching performance, and the conveying and releasing effects are better.

The invention discloses modified radix puerariae, radix scutellariae and rhizoma coptidis decoction with an intestinal flora regulating function for treating ulcerative colitis, and the modified radix puerariae, radix scutellariae and rhizoma coptidis decoction is mainly prepared from the following raw materials in parts by mass: 20-28 parts of radix puerariae, 6-12 parts of radix scutellariae, 6-12 parts of rhizoma coptidis, 3-9 parts of honey-fried licorice root, 3-9 parts of radix paeoniae alba, 6-12 parts of fructus jujubae, 9-15 parts of vinegar schisandra chinensis and 1-6 parts of fructus evodiae. According to the modified radix puerariae qinlian decoction (MGQD) disclosed by the invention, cold and warm medicines are used together, so that the effects of clearing heat and tonifying healthy qi are achieved, the imbalance of intestinal flora of ulcerative colitis can be effectively reversed, the diversity of the intestinal flora can be enhanced, the relative abundance of beneficial bacteria such as Muriacaceae, Lacnospiraceae NK4A136group and Lactobacillus can be increased, the level of metabolite bile acid of the intestinal flora can be regulated, and the curative effect of the ulcerative colitis can be improved. According to the traditional Chinese medicine composition, the protein expression of TGR5 and FXR in a colon tissue is up-regulated, the injury caused by colitis is relieved, inflammatory cell infiltration of the colon tissue is reduced, the number of goblet cells is increased, the symptoms such as stomachache, diarrhea and hematochezia can be effectively improved clinically, the illness state is controlled to be stable, the recurrence period is prolonged, and recurrence is reduced.

The invention discloses a decoction for treating liver and gallbladder damp-heat type acute bile pancreatitis and a preparation method thereof, and aims to solve the problems of biliary tract obstruction and viscera obstruction. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 14 to 18 parts of radix geutianae, 14 to 18 parts of fructus gardeniae, 14 to 18 parts of radix angelicae sinensis, 14 to 18 parts of radix rehmanniae, 14 to 18 parts of fructus forsythiae, 14 to 18 parts of caulis bambusae in taeniam, 28 to 32 parts of cortex moutan, 28 to 32 parts of herba patriniae, 48 to 52 parts of herba artemisiae scopariae, 7 to 11 parts of cortex magnoliae officinalis, 14 to 18 parts of rhizoma corydalis and 7 to 11 parts of radix aucklandiae. The raw materials are weighed according to the proportion and components and prepared into decoction, and mirabilite is added for taking after being mixed with water. The traditional Chinese medicine composition has the effects of clearing liver, benefiting gallbladder, relaxing bowels and relieving pain, can effectively control the development of illness conditions and relieve dry and bitter mouth, stomachache and abdominal distension symptoms, and is rapid in curative effect and low in price.

The application belongs to the technical field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition for treating irritable bowel syndrome, and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials by extraction: Fructus Evodiae 1-10 parts, Terminalia chebula 3-15 parts, ginseng tablet 1-10 parts, fried Radix Paeoniae Alba 5-20 parts, Radix Saposhnikoviae 5-18 parts, Cinnamomum cassia 2-15 parts, Radix Paeoniae Alba 2-10 parts, Herba Agrimoniae 5-15 parts, dried ginger 2-10 parts, Pericarpium Citri Reticulatae 2-12 parts, and Radix Glycyrrhizae 2-15 parts. The traditional Chinese medicine composition has the effects of invigorating the spleen and warming the kidney, astringing the intestines and stopping diarrhea, and relieving pain, and is suitable for the patients with diarrhea type irritable bowel syndrome and with the syndrome of deficiency of the spleen and kidney yang. Clinical research shows that the traditional Chinese medicine composition has a sustained clinical effect in relieving the main symptoms such as diarrhea and abdominal pain, and improving the traditional Chinese medicine syndromes, and the effect has an increasing trend with the extension of the treatment cycle.

The invention discloses a pharmaceutical composition for treating ulcerative colitis and application thereof, and belongs to the field of biological medicine. According to the Mongolian medicine theory guidance, a hot composition containing pomegranate, fructus piperis longi and the like is scientifically compatible with a cold composition containing radix aconiti agrestis buds, musk and the like, and a pharmaceutical composition with a remarkable treatment effect on ulcerative colitis is developed. The pharmaceutical composition realizes multi-target synergistic treatment, can regulate stomach fire, resist inflammation and bacteria, kill stickiness and clear heat, and effectively improves symptoms such as abdominal distension, hypogastralgia, diarrhea and borborygmus of ulcerative colitis patients. The enema is innovatively adopted and directly acts on the colon focus, the first-pass effect is avoided, the medicine utilization rate is increased, and a new treatment strategy is provided for clinical treatment of ulcerative colitis.

The present invention relates to a method for determining and quantifying proteose peptones derived from β-casein. This method comprises the steps of (i) providing a dairy-based product for analysis; (ii) subjecting the product to liquid chromatography-mass spectrometry analysis; and (iii) determining and / or quantifying the proteose peptones derived from β-casein in the product by detecting compounds with defined m / z values ​​or by deconvolving the mass spectra to calculate monoisotopic masses. The present invention also relates to nutritional compositions having a reduced content of proteose peptones derived from β-casein and their uses, for example, treating, preventing, and / or alleviating abdominal pain in infants.

The invention discloses a traditional Chinese medicine navel application agent for activating an abdominal cavity immune network and a preparation method thereof, through specific compatibility of 11 pungent and warm medicines (including five medicines for resolving dampness with aromatics, five medicines for warming the interior and one medicine for astringing the intestine), and in combination with a superfine grinding technology (the particle size is less than or equal to 30 microns) and a beta-cyclodextrin inclusion process, the transdermal absorption rate of the medicines is increased to 3-5 times that of common navel therapy. Animal experiments show that the preparation can increase the phagocytic rate of macrophages in the abdominal cavity of a mouse by 32.7%, the CD4 + / CD8 + ratio of T lymphocytes is recovered from 1.2 to 1.8 + / -0.2, and the slgA concentration of mucous membranes is increased by 2.3 times. Clinical observation shows that the effective rates for diarrhea, stomachache and vomiting symptoms caused by deficiency-cold of spleen and stomach of children within 24 hours respectively reach 90.2%, 85.6% and 80.4%, and liver and kidney dysfunction is not found.

The application discloses a traditional Chinese medicine health-care patch with the functions of regulating qi and inducing defecation and a preparation method thereof. The traditional Chinese medicine health-care patch adopts a traditional Chinese medicine paste which comprises the following components in parts by weight: 50-70 parts of radix codonopsis, 50-70 parts of cyperus rotundus, 20-40 parts of amomum villosum, 20-40 parts of syzygium aromaticum, 20-40 parts of cinnamomum cassia, 20-40 parts of angelica sinensis, 35-55 parts of perilla leaf, 20-40 parts of pachystachys johnstonii, 10-20 parts of radix rhei, 10-20 parts of cumin, 20-40 parts of honey-fried licorice, 50-70 parts of honey-roasted foxtail millet, 20-40 parts of saussurea lappa, 35-55 parts of long-jointed knotweed root, 10-20 parts of vinegar, 10-20 parts of yellow rice wine, 5-15 parts of lubricant and 400-500 parts of honey. The traditional Chinese medicine health-care patch can significantly increase the small intestine propulsion rate of constipated mice through a mouse test, and has a significant curative effect on functional constipation through a human efficacy test, with a total effective rate of 93.9%, and the improvement of abdominal distension and abdominal pain symptoms of constipated children is particularly obvious, so that the traditional Chinese medicine health-care patch has a very good effect of regulating qi and inducing defecation.

The invention discloses a traditional Chinese medicine composition for treating ulcerative colitis in an active stage as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 5-35 parts of humifuse euphorbia herb, 3-12 parts of carbonized sanguisorba root, 3-12 parts of sophora flower, 3-12 parts of madder, 3-12 parts of cacumen biotae, 1-6 parts of rhizoma bletillae, 0.5-5 parts of pseudo-ginseng, 2-10 parts of hairyvein agrimony and 3-12 parts of crinis trachycarpi. The traditional Chinese medicine composition has the advantages that the effects of clearing heat, cooling blood, astringing to stop bleeding, diminishing swelling and promoting tissue regeneration are achieved through synergistic interaction of the medicines, the traditional Chinese medicine composition is accurately adapted to the core pathogenesis of damp-heat accumulation, injury to blood collaterals due to heat and bleeding due to blood heat in the active period of ulcerative colitis, and the traditional Chinese medicine composition is especially suitable for active-period patients with blood, stomachache and tenesmus as main manifestations and is high in curative effect pertinence.