The invention discloses a method, device and equipment for predicting the fatigue life of a connecting piece, a medium and a program product, and belongs to the technical field of mechanical structural parts, and the method comprises the following steps: obtaining a CT scanning image of a connecting piece area, and calculating a performance reduction coefficient in combination with a standard sample fatigue test; key macroscopic mechanical parameters of the
base metal and the
welding flux are obtained, a macroscopic mismatch factor is calculated, and a
microstructure non-uniformity factor is calculated according to microhardness distribution of the connecting piece; equivalent load conversion of the environmental
impact factors is calculated; correcting the finite
element model based on a performance reduction coefficient, a macroscopic mismatch factor, a
microstructure non-uniformity factor and equivalent load conversion; and based on the corrected finite
element model, obtaining a fatigue life prediction result of the connecting piece. According to the method, the mechanical influence of the defects of the connecting piece is accurately quantified, and the material
influence factor and the environment
influence factor are considered, so that multi-source collaborative
coupling correction is formed, and the fatigue life prediction precision of the connecting piece is effectively improved.