The invention relates to a Cornus officinalis fruit wine and a preparation method thereof. Raw materials of the Cornus officinalis fruit wine comprise dried Cornus officinalis fruit flesh, Medlar, Licorice, Epimeddium, Radix Astragali, Chinese magnoliavine, Chinese dates, white sugar and purified water. The preparation method comprises putting the dried Cornus officinalis fruit flesh, the above Chinese medicinal materials and sugar solution prepared by the white sugar and the purified water into a fermentation cylinder, carrying out a dry yeast inoculation in the fermentation cylinder to carry out primary fermentation with stirring well to obtain primary fermentation products, feeding the peeled primary fermentation products into the fermentation cylinder to carry out after-fermentation, when the after-fermentation is finished, collecting fermentation liquor from the fermentation cylinder to put the fermentation liquor into a wine clarification tank for clarification of the fermentation liquor, wherein during the clarification, the fermentation liquor and additives are stirred well and then are sealed and stand for multiple days, segregating pure mellow wine produced by the clarification and wine dregs, putting the pure mellow wine into a clean stainless steel tank, controlling and adjusting physical and chemical indexes comprising a sugar degree, an acid degree and an alcoholic degree for the pure mellow wine to make the physical and chemical indexes meet standards, wherein sweet wine has an alcoholic degree of 9% to 12% (v/v), and carrying out a low temperature brewing process on the pure mellow wine having the physical and chemical indexes standardized to obtain Cornus officinalis sweet fruit wine.