The present invention discloses a screw-type terminal block, including a housing, a conductive member is fixedly installed inside the housing, the end of the conductive member is located in a wire pressing frame, and the wire can be fixedly clamped between the wire pressing frame and the conductive member by tightening the screws. The wire pressing frame is composed of an upper nut block and a lower U-shaped clamp, protrusions are provided on both sides of the nut block, and clamping holes are provided on both sides of the U-shaped clamp, the protrusions and the clamping holes are snap-connected, an inwardly inclined inclined guide surface is provided on the upper side of the protrusion, a dividing groove is provided in the middle of the bottom of the U-shaped clamp, and anti-slip teeth are formed on the outside of the dividing groove. The wire pressing frame of the present invention has a good self-locking effect, when the nut block moves upward, the inwardly inclined inclined guide surface on the protrusion can act on the clamping hole of the U-shaped clamp, and the U-shaped clamp is deformed inwardly to achieve locking; the bottom of the U-shaped clamp is provided with a dividing groove and anti-slip teeth, which can increase the friction when clamping the wire, and the wire is less likely to be pulled out.