37results about How to "Low requirement" patented technology

An active CMOS biosensor chip for fluorescent-based detection is provided that enables time-gated, time-resolved fluorescence spectroscopy. In one embodiment, analytes are loaded with fluorophores that are bound to probe molecules immobilized on the surface of the chip. Photodiodes and other circuitry in the chip are used to measure the fluorescent intensity of the fluorophore at different times. These measurements are then averaged to generate a representation of the transient fluorescent decay response unique to the fluorophores. In addition to its low-cost, compact form, the biosensor chip provides capabilities beyond those of macroscopic instrumentation by enabling time-gated operation for background rejection, easing requirements on optical filters, and by characterizing fluorescence lifetime, allowing for a more detailed characterization of fluorophore labels and their environment. The biosensor chip can be used for a variety of applications including biological, medical, in-the-field applications, and fluorescent lifetime imaging applications.

A detector (110) for determining a position of at least one object (112) is proposed. The detector (110) comprises: —at least two optical sensors (118, 120, 176), each optical sensor (118, 120, 176) having a light-sensitive area (122, 124), wherein each light-sensitive area (122, 124) has a geometrical center (182, 184), wherein the geometrical centers (182, 184) of the optical sensors (118, 120, 176) are spaced apart from an optical axis (126) of the detector (110) by different spatial offsets, wherein each optical sensor (118, 120, 176) is configured to generate a sensor signal in response to an illumination of its respective light-sensitive area (122, 124) by a light beam (116) propagating from the object (112) to the detector (110); and—at least one evaluation device (132) being configured for determining at least one longitudinal coordinate z of the object (112) by combining the at least two sensor signals.

This present disclosure provides reliable methods and apparatus for delivering a pharmaceutical active ingredient to a substrate. In some examples, the pharmaceutical active ingredient is applied to the substrate after the substrate has been fully prepared. The substrate can be an edible product or an inedible substrate. The edible product can be a baked or otherwise cooked good. In some examples, the edible product can be fruits and / or nuts. The method and apparatus for delivering the pharmaceutical agent can be configured to deliver microquantities of the pharmaceutical active ingredient to the substrate.

A laser including a semiconductor laser stack group, a beam compositor, a pump beam collimator, a thin-disk laser crystal, a first and a second parabolic reflectors with the same facial contour function, a corrective reflector, an output mirror, and a jet-flow impact cooling system. The thin-disk laser crystal and the output mirror form a laser resonant cavity. The first parabolic reflector, second parabolic reflector, thin-disk laser crystal, and corrective reflector form a multi-pumping focus cavity. The jet-flow impact cooling system is used for cooling the thin-disk laser crystal. The pump light produced by the semiconductor laser stack group is composited by the beam compositor, collimated by the pump light collimator, and enters the multi-pumping focus cavity. Within the multi-pumping focus cavity, the pump light is focused, collimated, and deflected to converge on the thin-disk laser crystal. The laser resonant cavity produces and outputs a laser beam.

A preparation method for solid film dip-coated with a novel chiral recognition agent belongs to the technical field of film separation. The method comprises: synthesis of a cyclodextrin-type chiral ionic liquid; preparation of a crosslinking solution; treatment of base film; soaking of film sheets in a chiral ionic liquid / chitosan crosslinking solution or a polyanionic film-making solution and a chiral ionic liquid film-making solution; washing of composite film sheets; and drying of film sheets. The method for preparing chiral solid film is easy, few in steps and low in requirements on equipment. Chiral separation experiments show that the use of the chiral separation solid film prepared by the method can realize high selectivity and low energy consumption in chiral separation processes.

The invention relates to a centering process method for an electron beam of a plane annular welding line, wherein the electronic beam is welded along the track of the plane annular welding line based on the linkage of the axis X and axis Y of a plane coordinate system. Through the invention, the common complex centering way is simplified, quick and precise centering of the plane annular welding line is realized, the production efficiency is improved by 300%, the welding line quality is effectively improved, the filament loss of an electron gun is reduced, and the requirement on the working experiment of an operator is lowered. The process method is adopted for quickly and precisely centering and welding the electron beam of the plane annular welding line for the first time in the country; the process method is applied to the welding and production of the electron beam of various plane annular welding line parts of an aircraft engine as well as the welding and production of the electron beam of various parts of a gas turbine and other similar structures. The process method has great predictable economic value and social values.

Production of de novo hydrophobic poly-azole film is carried out by taking wetted conductive poly-azole with switch property as raw material, selecting non-smooth substrate BCP to increase roughness, converting oxygenated hydrophilic property into hydrophobic property, controlling corresponded oxygenated hydrophobic property, depositing poly-azole thin-layer on surface selectively by electrochemical method and changing polymerization time to obtain the final product. It can decrease experimental parameter during process of polymerization and have polymer conductive product.

A signal processing device utilizes a stochastic approximation of a gradient descent algorithm for updating a transform. The signal processing device is configured to implement the transform for producing a desired transformed output signal, and the transform is updated using the stochastic approximation of the gradient algorithm based on received data associated with the signal being processed. The transform is represented in a reduced-parameter form, such as a Givens parameterized form or a Householder form, such that the reduced-parameter form for an N×N transform comprises fewer than N2 parameters. The updating process is implemented using computations involving the reduced-parameter form, and an adaptation of the transform is represented directly as one or more changes in the reduced-parameter form. The gradient algorithm may be configured to minimize a negative gradient of a pairwise energy compaction property of the transform. Advantageously, the gradient algorithm may be made locally convergent in mean for a specified step size. The invention can also be implemented in a backward adaptive form in which the updating process is driven by quantized data.

An image-processing method includes obtaining an image including a target object, the image being formed by an array of pixels. A current frame portion is extracted from the image, the frame portion being at least a portion of the pixels forming the image, corresponding to a region of interest in the image, the region of interest comprising the target object. A previously calculated current super-resolved frame portion is provided, corresponding to the region of interest in the image. An updated super-resolved frame portion is calculated from the current frame portion and the current super-resolved frame portion.

A method of preparing an additive suspension circuit for a hard disk drive suspension includes electrodepositing an alloy of copper using an electrolytic bath containing copper sulfate, tin, iron, sulfuric acid, and hydrochloric acid, using pulsed current of about 10-45 amperes per square foot.

Disclosed is a method of catalytic oxidation of lignite using oxygen as an oxidant at atmospheric pressure, belonging to a method of mild oxidation of lignite. The method is used to mildly oxidize the lignite using the oxygen as the oxidant under the action of a nitroxide radical catalyst and a metal salt or metal oxide cocatalyst; the process comprises the following steps: pulverizing the lignite to 200 meshes or less, drying a pulverized coal sample at a temperature of 80° C. in vacuum for 10 h, weighing 0.5 g of the treated coal sample, sequentially adding 10 ml of acetic acid, 0.5 mmol of a catalyst and 0.15 to 0.25 mmol of a cocatalyst into a round-bottom flask, connecting a tee joint to an upper orifice of a condenser pipe, replacing oxygen in vacuum for three times so that the round-bottom flask is filled with the oxygen, keeping oxygen pressure at 0.1 MPa, reacting at a temperature of 80° C. to 120° C. for 4 to 12 h; filtering after the reaction is finished; decompressing a filtrate to remove the acetic acid, adding a small amount of ethyl acetate to dissolve, then using an excess CH2N2 / ether solution to esterify for 10 h at room temperature, using 0.45 μm filter paper to filter, and analyzing an esterified product through a gas chromatography-mass spectrometer. The method has the advantages of using the oxygen as the oxidant, having low price, having no toxicity, and achieving environmental protection and mild conditions.

The present invention has the advantages of simple structure, low detection cost, high measurement precision, high detection speed, strong practicability, etc. The present invention relates to a novel array photoelectric sensor grating displacement detection system and method. The system includes a parallel light source, an incremental glass grating ruler, photoelectric sensor arrays, a high-speed voltage comparator, a signal processing unit and a displacement display unit, wherein the incremental glass grating ruler is perpendicular to an irradiation direction, of the parallel light source.

The invention discloses a preparation method of a prostaglandin derivative. The method comprises the following steps: protecting corresponding hydroxyl in a prostaglandin intermediate body with alkoxy benzyl; and performing a hydrogenation reaction under a normal pressure to prepare a corresponding prostaglandin derivative. According to the method, the reaction condition is reduced, and the yield is improved. The method is more suitable for industrial production.

Provided is a primary clarification depth filtration process of cell-culture feeds, including chemically treated flocculated feeds, containing target biomolecules of interest such as mAbs, mammalian cell cultures, or bacterial cell cultures, utilizing a primary clarification depth filtration device containing a media with significantly lower flushing requirements, resulting in lower levels of organic extractables released after media flushing, and increased throughput for the pre-treated feed streams, without the use of a primary clarification centrifugation step or primary clarification tangential flow microfiltration step. The primary clarification depth filtration device used in the primary clarification of fluid cell culture feeds, including chemically treated flocculated feeds containing flocculated cellular debris and / or colloidal particulates having a particle size distribution of about 0.5 μm to 200 um, contains a porous depth filter media having porous layers of varying pore ratings, and achieves the desired level, of total organic extractables (1-3 ppm) measured in the feed filtered through the media with, significantly lower flushing requirements. Kits and methods of using and making the same are also provided.

The present invention relates to magnets and to magnetic resonance imaging systems. The magnet is open with magnetic coils arranged in quadrant, separated about two perpendicular planes, a midplane and a plane of reflection, and wherein the windings are configured such that, in operation, current flow is symmetrical about the plane of reflection and anti-symmetrical about the midplane, to produce a nett magnetic field at the centre in a direction perpendicular to the plane of reflection.

Toner for developing electrostatic images including core particles that contain a colorant, a binder resin, and a wax, and exhibiting low-temperature fixability, high-temperature anti-offset property, image durability, flowability, high-temperature preservability, and low particle emission rate.

The present invention provides a perfluorophosphate-based drag-reducing agent for gas pipelines. Raw materials for the perfluorophosphate-based drag-reducing agent for gas pipelines consist of fatty acid(s), pyridine(s), fluorophosphates(s) and haloalkane(s) in a mass ratio of 2:1:1:1 to 2:3:1:2. A method for preparing the perfluorophosphate-based drag-reducing agent for gas pipelines is also provided. The perfluorophosphate-based drag-reducing agent for gas pipelines is non-toxic and environmentally friendly, has a high drag reduction percentage, a long-lasting effect, good stability and solubility, does not affect the inner surface and coatings of natural gas pipelines or gas quality, and is suitable for on-line atomization and injection.

A conductive adhesive mixture includes a component A which is 0.1% to 28% of the dry weight of the conductive adhesive mixture and a component B which is 72% to 99.9% of the dry weight of the conductive adhesive mixture. The component A is selected from one or more of the group consisting of SnCl4, InCl3 and SbCl3; and the component B is selected from one or more of the group consisting of K2O.nSiO2, Na2O.nSiO2, (SiO2)n and Al2O3. The conductive adhesive mixture, having good electrical conductivity, is used for preparation of the fluorescent screen anode plate, greatly improving the life of the luminous layer, thus improving the life and light efficiency of the field emission device. The present invention further provides a fluorescent screen anode plate manufactured with this conductive adhesive mixture and the manufacturing method thereof.

Disclosed is a method for estimating dense multipath parameters by means of multipolarized broadband extended array responses, which includes: first transmitting multiple different transmitted signal sequences via a multipolarized antenna array, and processing received data in multiple snapshots according to the known transmitted signals, to obtain channel responses of multipolarized antenna components at all frequency points in a frequency band; extending the obtained channel response matrixes of multiple frequency points in multiple snapshots into a large two-dimensional channel response matrix; then, acquiring a delay parameter regarding multipath propagation by using a reference array element, and estimating two-dimensional departure and arrival angles by using a channel matrix subjected to frequency domain smoothing and dimensionality reduction; and afterwards, pairing the estimated departure and arrival angles, and estimating parameters such as the cross-polarization ratios, the initial phases, and the amplitudes of the sub-paths by using the estimated parameters.