The invention provides a preparation method of an oral
oxiracetam preparation suitable for old people to take. Medicines and auxiliary materials are reasonably compatible and are granulated and tableted through a
fluidized bed to prepare the preparation, the preparation can quickly disintegrate in the
oral cavity under the waterless condition (or under the condition that only a small amount of water exists) and enter the
digestive tract with
swallowing actions, is consistent with a common tablet in the body about behaviors and is very suitable for
old patients difficulty in
swallowing. The prepared orally disintegrating
oxiracetam tablet is reasonable in composition, prepared
fluidized bed granules are thin, small and uniform, the
angle of repose ranges from 30 degrees to 35 degrees, the liquidity is good, tablets do not break or is not softened or sticky,
astringent and odd
flavor phenomena do not occur in the
tableting process, and the
hardness of the prepared disintegrating
oxiracetam tablet is 35-50 N. The disintegrating
time limit is 30-40 S, the taste is better, no gravel feeling exists, the
dissolution rate accumulated within 20 minutes exceeds 80%, and the oral oxiracetam preparation does not need special production conditions, has the advantages of being low in production cost and convenient to carry, store, transport and take, improves the taking compliance of patients and has a higher practical value.