The invention discloses a vertical centrifugal separation discharge grinding system. The vertical centrifugal separation discharge grinding system comprises a grinding cavity, a grinding rotor, and adischarging and separating rotor mechanism, wherein the grinding rotor is in linkage with a second rotating shaft by adopting a splicing structure, the inner side and the outer side of the grinding cavity are sealed through mechanical seal, a hollow structure is adopted at the front end of the grinding rotor, the second rotating shaft is driven by a second driving mechanism to rotate at a high speed, materials enter the grinding cavity from a feeding port through pumping, under the action of the rotation of the grinding rotor, the materials and a grinding medium are driven to collide with andrub with one another, and the materials flow towards a discharging and separating rotor. The vertical centrifugal separation discharge grinding system is simple in structure and ingenious in design, avertical structure, centrifugal separation, and free-net discharging are adopted, a screen is not additionally arranged, so that the problems that in the prior art, the discharging screen is easy toblock, the flow is small, the cleaning is difficult and the ball leakage are solved.