The invention relates to the technical field of soles and vamps, in particular to shoe outsole and vamp with cattlehide powder and a manufacturing method of the shoe outsole and vamp. The shoe outsole and vamp comprise a shoe outsole body and a vamp body, bonding layers are arranged on the bottom face of the shoe outsole body and the face portion of the vamp body, and the cattlehide powder is sprayed to the bonding layers. The method comprises the following steps of a, body pretreatment, b, gluing and c, powder spraying. Compared with the prior art, the cattlehide powder can be sprayed to shoe outsoles and vamps of different materials at the same time, bonded leather is formed, skid resistance is achieved, attractiveness and environment friendliness are achieved, full-automatic procedures are achieved in the manufacturing method of the shoe outsole and vamp, efficiency can be improved, stereoscopic spraying is achieved on the shoe outsole and vamp, the cattlehide powder is evenly sprayed, the thickness degree can be adjusted, and product quality can be improved.