The invention relates to the field of fireproof materials, particularly to a magnesium-calcium-titanium-carbon brick and a preparation method of the brick. The brick is characterized in comprising the following raw materials based on weight: sintered dolomite sand, fused magnesite, graphite, asphalt powders, anhydrous resin, urotropine, an antioxidant and industrial titanium dioxide. Compared with the prior art, the magnesium-calcium-titanium-carbon brick has the following beneficial effects: (1) the brick can be widely applied to various external refining devices such as LF (ladle furnace), VAD (vacuum arc degassing) furnace, VOD (vacuum oxygen decarburization) furnace, AOD (argon oxygen decarburization) furnace, RH (recirculation degassing) furnace, GOR (gas oxidation refining) furnace, ASEA-DKF and K-OBM-S, thereby having wide application value; (2) the brick can resist against corrosion, endure peeling, and has good high-temperature vacuum stability, and the product is small in re-burning line change, good in thermal shock stability, and not limited by intermittent usage conditions; (3) the product has excellent hydration resistance; and (4) the brick does not contain water or need any external water, so that the magnesium-calcium fireproof material can be effectively protected from hydration, and the brick is especially fit for matching with the magnesium-calcium fire brick.