44 results about "Resonance fluorescence" patented technology

A grating-based sensor is disclosed that has a grating structure constructed and designed for both evanescent resonance (ER) fluorescence detection and label-free detection applications. Some embodiments are disclosed which are optimized for ER detection in an air mode, in which the sample is dry. Other embodiments are optimized for ER detection in liquid mode, in which the sample is suspended in liquid medium such as water. One and two-dimensional gratings are also disclosed, including gratings characterized by unit cells with central posts, central holes, and two-level, two-dimensional gratings. A readout system for such sensors is also disclosed. One embodiment includes a first light source optimized for collecting label-free detection data, a second light source optimized for collecting ER fluorescence amplification data, and at least one detector. In one embodiment, the detector is an imaging system and includes a CCD camera for collecting both ER and label-free data. In other embodiments, the at least one detector takes the form of a spectrometer for collection of label-free data and a photomultiplier for collecting ER data. In other embodiments, a single light source such as a tunable laser or broad band light source is used.

Quantum resonance fluorescent microscope systems for detecting component substances in a specimen are described. The systems are based on exciting the sample containing the material with a femtosecond to nanosecond probe pulse of collimated light, which is tailored to optimize detection of a given material by separating the probe pulse into component features of frequency, polarization, phase and / or amplitude. The component features are independently shaped and formed into a composite pulse selected to optimize a signature response pulse received from the material. In some cases, two independently re-shaped pulses are combined, where one re-shaped pulse has two mixed polarization states and the other re-shaped pulse is linearly polarized. These two pulses are made to intersect at an angle of 90 degrees so that the combined pulse has electric field in each of the XYZ axes. Selection of the appropriate shapes for the component features of the pulses for a given material is accomplished by testing variations in the features on the material, assigning a fitness value to variants that tend to optimize a distinctive spectral response from the material, and using a genetic algorithm to select the combination of component features that enhances the distinctiveness of the response received over a typical background.

A grating-based sensor is disclosed that has a grating structure constructed and designed for both evanescent resonance (ER) fluorescence detection and label-free detection applications. One and two-dimensional gratings are also disclosed, including gratings characterized by unit cells with central posts, central holes, and two-level, two-dimensional gratings. A readout system for such sensors is also disclosed. Various applications for the biosensors are described, including cell-based assays for assessing the effect of drug compounds, proteins, peptides and other materials on cell function. A biosensor embodiment optimized for a luminescent response at two different wavelengths is also described. Such luminescent response could be produced by fluorescence (either native or from an attached fluorophore), phosphorescence, chemi-luminescence, or other luminescence technology. Two different luminescence technologies could be combined on the same biosensor chip.

A method for classifying a sample based upon a complete spectral analysis. The sample is illuminated with penetrating radiation and an initial complete spectral analysis is performed based on spectral resolution of resonant fluorescence lines emitted at the surface, or within the volume, of the sample. If the initial complete spectral analysis yields the composition of the sample to within acceptable limits, analysis values are output to the user. Otherwise, further analysis, informed by the results if the initial complete spectral analysis, is performed.

The invention relates to an on-line in-water heavy metal monitor based on atomic fluorescence spectroscopy. The monitor comprises a feeding-reacting system, an atomization system and an optical system, wherein the feeding-reacting system is used for quantitatively introducing a water sample or a standard solution into an instrument to be reacted with a reducing agent so as to generate heavy metal hydride in a gas state; the heavy metal hydride is carried by a carrier gas and enters the automation system after being subjected to water-gas separation; the hydride in the gas state is decomposed into metal atoms at appropriate temperature; under the triggering action of a specific wavelength triggering light of the optical system, the metal atoms in the gas state generate resonance or non-resonance fluorescence; and by measuring the fluorescence intensity, the quantitative result of the heavy metal element is obtained. The advantages of the atomic fluorescence spectroscopy analysis principle is sufficiently utilized, the rapid high-sensitivity on-line monitoring on the in-water heavy metal elements is realized, and the problem of analysis interference is avoided to the maximum extent.

A light source is gated ON and OFF in response to a pulsed signal. Photo emissions from the light source are coupled to a material under test. Resonant fluorescent emissions from the material are coupled to a photodiode. Current from the photodiode is coupled into an amplifier system comprising a first and second amplifier stages. The first amplifier stage is gated to a low gain when the light source is turned ON and the gain is increased when the light source goes from ON to OFF. The second amplifier stage has digitally programmable offset and gain settings in response to control signals. The output of the second amplifier stage is digitized by an analog to digital converter. A controller generates the pulse control signal and the control signals.

The broadening of the lines in NRF from an isotope that is part of a material may be due to several causes: the temperature of the material, the molecular structure of the material and the crystalline structure of the material. By measuring the broadening caused by the molecular structure and the crystalline structure the material itself can be identified. The exact energy of the lines in NRF may also depend on the nature of the crystalline and molecular structure of the material. By measuring the changes in the energy of the NRF lines caused by the structure of the material the material itself may be identified. These techniques provide a “fingerprint” of the molecule or crystal that is involved. The fingerprint information may be used to determine a potential threat.

Isotope identification imaging of nuclear fuel material or explosives concealed in a drum or container in which nuclear reactor fuel or radioactive waste are sealed is realized while ensuring high precision, high reliability, and safety. A sample 31 is irradiated with laser Compton photon beams 21 and 22 generated by a collision between an electron beam 12 and polarized laser light 16 and 20. An isotope in the sample is identified using nuclear resonance fluorescence, and the spatial distribution thereof is imaged. In so doing, a nuclear level of an isotope whose emission direction of nuclear resonance fluorescence is dependent on the planes of polarization of the incident LCS photon beams is used.

The invention relates to a heterogeneous photocatalysis resonance fluorescence method for accurately detecting trace uranium in an environmental water sample. The method mainly comprises the following steps: quantitatively separating the trace uranyl in a complex environmental water sample by using solid phase extraction particles UMIP having a specific recognition and adsorptive action on UO2<2+>, and adsorbing the trace uranyl to the surface of the UMIP to form a uranium-containing molecularly imprinted polymer; then accurately detecting the content of the uranium by the heterogeneous photocatalysis resonance fluorescence method. The method has the characteristics of high sensitivity, high specificity, high matrix interference resistance, simplicity, quickness and low cost. The invention also discloses a heterogeneous photocatalysis kinetic analysis and detection device which comprises a photocatalytic reaction system, a low-heat high light source, an air-cooled constant temperature system and an electromagnetic-stirring system.

The invention relates to a whole day photon counting laser radar device and a method, which comprises an emission system consisting of a laser, an expander and a reflector, a receiving system consisting of a telescope, an optics filter and a photoelectric detector, and a central control device connected with the photoelectric detector with a software. The invention is characterized in that the wavelength of the laser and the optics filter are chosen to match with the fraunhofer absorption line wavelength of the solar spectrum; the intense absorption is adopted to reduce the intensity of a solar back light by 80 to 90 percent and to lead the laser radar to have good photon counting ability under the back light condition in days. The invention is characterized in that the day detection signal-noise ratio and the detection distance are greatly improved, which effectively improves the whole day high-performance working ability. Besides, the invention is widely suitable for the laser radarof detecting weak signal such as Mie dispersion, Rayleigh dispersion, Raman dispersion and atom resonance fluorescence, etc.