233 results about "Tuberculous osteomyelitis" patented technology

The invention relates to a method of treating or monitoring / diagnosing a disease state mediated by activated macrophages. The method comprises the step of administering to a patient suffering from a macrophage mediated disease state an effective amount of a composition comprising a conjugate or complex of the general formulaAb−Xwhere the group Ab comprises a ligand capable of binding to activated macrophages, and when the conjugate is being used for treatment of the disease state, the group X comprises an immunogen, a cytotoxin, or a compound capable of altering macrophage function, and when the conjugate is being used for monitoring / diagnosing the disease state, X comprises an imaging agent. The method is useful for treating a patient suffering from a disease selected from the group consisting of rheumatoid arthritis, ulcerative colitis, Crohn's disease, inflammation, infections, osteomyelitis, atherosclerosis, organ transplant rejection, pulmonary fibrosis, sarcoidosis, and systemic sclerosis.

Described herein are devices, systems and methods for treating disease and / or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.

The invention relates to the medical instrument field, especially relates to the orthopaedics titanium alloy internal fixation field. The invention provides an intramedullary nail having a multifunctional coating and a preparation method. The intramedullary nail comprises a multifunctional composite medicament coating slow release system, and the slow release system comprises a porous transition layer and a degradable coating containing the medicament. The intramedullary nail integrates the functions of preventing, treating infection and internal fixation as one, and is mainly used for treating adaptation diseases such as open fracture and osteomyelitis, and has the effect for degrading and slowly releasing the medicines.

The invention relates to the use of tanshinone IIA in the preparation of medicaments for treating atherosclerosis, myocardial infarction, coronary heart disease, tumor, purulency osteomyelitis and tonsillitis. The tanshinone IIA of the invention can be prepared into various dosage types.

The invention relates to a medicine-carried injectable calcium sulfate based slow-release implant composition and application thereof. The slow-release implant composition adopts a component A and a component B, wherein the component A comprises 100 portions of semi-hydrated sulfuric acid, 0.1 to 10 portions of nucleater, 0.1 to 5 portions of plasticizer, 0 to 5 portions of surfactant and 2 to 5 portions of medicine-carrying particles, and the medicine-containing mass concentration is between 4 and 20 percent; and the component B is a diluent, and the weight of the diluent is 30 to 60 portions as calculated by 100 portions of the semi-hydrated sulfuric acid. The medicine-carried particle injectable calcium sulfate based slow-release implant system has the advantages that: the slow-release implant system can inject local medicine-release implant into focuses and make the implant formed without operation, overcome the defect that general preformed implant materials do not closely contact circumferential bone tissues, and prevent encapsulation of fiber tissues; due to the osteoacusis function of calcium sulfate, the slow-release implant system is more suitable for growth and repair of the bone tissues; and due to unique medicine-carried particles, the slow-release implant system can realize local medicine release, is stable to release medicines, has long medicine effect time and high medicine utilization rate, and is suitable for treating bone defect and the like caused by osteomyelitis, osteocarcinoma and the like.