The invention discloses a manufacturing method of a PCB, and a PCB manufactured by use of the method. The PCB comprises a PCB substrate and a protective cover plate. The protective cover plate is adhered to the PCB substrate through an adhesive coating, the adhesive coating is prepared by a low-flow glue material or a flow-free glue material, the PCB substrate is provided with a pad and a positioning hole, an installation hole is arranged at a position, corresponding to the pad, of the protective cover plate, a relief hole is arranged at a position, corresponding to the pad, of the adhesive coating, an LED chip is packaged inside the installation hole, the LED chip is electrically connected with the PCB substrate through the pad, alignment holes are arranged at positions, corresponding to the positioning hole, of the protective cover plate and the adhesive coating, and the positioning hole and the alignment holes are selectively aligned through an auxiliary positioning shaft. According to the invention, through a cooperative structure of the PCB substrate, the adhesive coating and the protective cover plate, gummosis on the surface of the pad position of the PCB substrate is avoided, and the integration density of the LED chip is improved. Besides, through a cooperative structure of the positioning hole, the alignment holes and the auxiliary positioning shaft, the alignment precision of the protective cover plate and the PCB substrate is effectively improved.