57results about How to "Inexpensive to synthesize" patented technology

The present invention relates to chalcone and chalcone derivatives and analogs which are useful as angiogenesis inhibitors. The present compounds, which are inexpensive to synthesize, exhibit unexpectedly good activity as angiogenesis inhibitors. The present invention also relates to the use of chalcone and its analogs as antitumor / anticancer agents and to treat a number of conditions or disease states in which angiogenesis is a factor, incluidng angiongenic skin diseases such as psoriasis, acne, rosacea, warts, eczema, hemangiomas, lymphangiogenesis, among numerous others, as well as chronic inflammatory disease such as arthritis.

The present invention relates to novel compounds and the use of said compounds as a medicament, as well as for the manufacture of a medicament for treatment of disorders relating to the binding of galectin to receptors in a mammal. Said galectin is preferably galectin-3.

A pixel-based display utilizes persistence-of-vision to sweep text and graphics in a cylindrical plane, including time and date, custom messages and animations. The display is generated from a light array with a column of modulated light emitting elements, which is mounted on a rotating display assembly. Power and data are combined on a fixed control assembly and inductively coupled to the display assembly. A control assembly processor interprets a display application language that describes display-specific tasks to generate command, mode, character and graphic data for the display assembly. The control assembly processor also reads a trigger position sensor and adds a trigger delay to generate a virtual trigger command, which provides for flexible display positioning and scrolling display effects.

A recyclable esterification or transesterification catalyst and methods for making and using the same are provided herein. The catalyst can be used to prepare biodiesel or methyl soyate from various feedstocks, including vegetable oils and animal fats. The catalyst can both esterify free fatty acids and transesterify mono-, di-, and triglycerides. The catalyst can also be combined with a metal oxide, and optionally calcined, prior to carrying out a catalytic reaction.

The present invention relates to an arylphenoxy catalyst system producing an ethylene homopolymer or copolymers of ethylene and α-olefins, and a method of producing an ethylene homopolymer or copolymers of ethylene and α-olefins having a high molecular weight under a high temperature solution polymerization condition using the same. The catalyst system includes a group IV arylphenoxy-based transition metal catalyst and an aluminoxane cocatalyst or a boron compound cocatalyst. In the transition metal catalyst, a cyclopentadiene derivative and arylphenoxide as fixed ligands are located around the group IV transition metal, arylphenoxide is substituted with at least one aryl derivative and is located at the ortho position thereof, and the ligands are not crosslinked to each other. The catalyst includes an environmentally-friendly raw material, synthesis of the catalyst is economical, and thermal stability of the catalyst is excellent. It is useful for producing an ethylene homopolymer or copolymers of ethylene and α-olefins having various physical properties in commercial polymerization processes.

The invention discloses a preparation method of an MIL-100(Fe) packaged phosphotungstic heteropolyacid catalyst. The preparation method comprises the steps of: adding raw materials for synthesizing phosphotungstic heteropolyacid into a certain amount of deionized water based on certain proportion; subsequently adding a certain amount of an iron source, mixing and stirring, further adding a certain amount of an organic ligand, mixing, stirring, adding a certain amount of an acid solution, and mixing and stirring; mixing, stirring and reacting for 5-20 hours under normal pressure at 80-95 DEG C; and filtering the obtained solid, washing for 10-20 hours at 60-80 DEG C by using absolute ethyl alcohol, subsequently treating for 10-15 hours at 60-80 DEG C by using a 30-60mmol / L ammonium fluoride solution, sufficiently washing by using deionized water, and finally drying for 5-10 hours at 100-200 DEG C so as to obtain the MIL-100(Fe) packaged phosphotungstic heteropolyacid catalyst. The method is temperate in synthesis condition, low in synthesis energy consumption and high in catalyst synthesis yield.

The present invention relates to a carbon nanotube transistor biosensor with aptamers and a method for detecting a target material using the same, more particularly to a carbon nanotube transistor biosensor recognizing the target material, i.e., a specific molecule (such as a protein, a peptide, an amino acid, and an organic / inorganic compound) by using DNA aptamers and a method for screening a target material using the same. In the biosensor of the present invention, the aptamers binding specifically to a particular protein are adsorbed on a carbon nanotube constituting the channel domain of carbon nanotube transistor to easily detect / identify a particular protein via the electric conductivity of carbon nanotube that varies if the particular protein is exposed to corresponding aptamers.

Process for the synthesis of hydrocarbon constituents of gasoline comprising catalytic conversion in a gasoline synthesis step of an oxygenate-containing feed comprising methanol and / or dimethyl ether and a mixture of at least on a total oxygenate basis 0.05 wt % C3+ higher alcohols and / or their oxygenate equivalents to hydrocarbon constituents of gasoline.

The present invention relates to a bis-arylaryloxy catalyst system for the production of ethylene homopolymers or copolymers with α-olefins, which has high catalytic activity. More particularly, it relates to a transition metal catalyst comprising a group-IV transition metal as a central metal, a cyclopentadiene derivative around the central metal, and two aryloxide ligands substituted with aryl derivatives at the ortho-positions, the ligands not being bridged to each other, as well as a catalyst system comprising said catalyst and an aluminoxane co-catalyst or a boron compound co-catalyst, and a method for producing high-molecular-weight ethylene homopolymers or copolymers with α-olefins using the same.

Disclosed herein is an apparatus and method for synthesizing carbon nanotubes, including a fuel supply unit for supplying a large amount of liquid metal catalyst mixture using a syringe pump for quantitatively supplying a liquid metal catalyst mixture, mixed with hydrocarbon-based liquid carbon sources such as xylene, toluene, benzene and the like, and metal catalytic particles, such as iron, nickel, cobalt, molybdenum and the like, and a general liquid pump for supplying a liquid metal catalyst mixture depending on the amount thereof; an evaporation unit for evaporating and atomizing the liquid metal catalyst mixture supplied from the fuel supply unit into precursors having a uniform size on the nanometer scale; a carrier gas supply unit for transferring particles atomized in the evaporation unit to a reactor and transferring carrier gas, having an influence on the synthesis of carbon nanotubes, to the reactor; a horizontally oriented reaction unit for synthesizing carbon nanotubes in large quantities using the carrier gas supplied from the carrier gas supply unit and the precursors formed in the evaporation unit; a filtering unit comprising a filter for filtering residual particles among the atomized particles synthesized into carbon nanotubes in the horizontally oriented reaction unit and some of the carbon nanotubes synthesized in the vapor phase; and a vacuum generation unit comprising a vacuum pump configured to be connected with the filtering unit, decrease pressure in the reactor, and remove oxygen remaining in the reactor, or a continuous collection unit in the case where the apparatus includes a vertical type reaction unit.

The present invention relates to chalcone and chalcone derivatives and analogs which are useful as angiogenesis inhibitors. The present compounds, which are inexpensive to synthesize, exhibit unexpectedly good activity as angiogenesis inhibitors. The present invention also relates to the use of chalcone and its analogs as antitumor / anticancer agents and to treat a number of conditions or disease states in which angiogenesis is a factor, including angiongenic skin diseases such as psoriasis, acne, rosacea, warts, eczema, hemangiomas, lymphangiogenesis, among numerous others, as well as chronic inflammatory disease such as arthritis.

Disclosed is an arylphenoxy catalyst system for producing an ethylene homopolymer or copolymers of ethylene and α-olefins, and a method of producing an ethylene homopolymer or copolymers of ethylene and α-olefins having a high molecular weight under a high temperature solution polymerization condition using the same. The catalyst system includes a group 4 arylphenoxy-based transition metal catalyst and an aluminoxane cocatalyst or a boron compound cocatalyst. In the transition metal catalyst, a cyclopentadiene derivative and arylphenoxide as fixed ligands are located around the group 4 transition metal, arylphenoxide is substituted with at least one aryl derivative and is located at the ortho position thereof, and the ligands are not crosslinked to each other. The catalyst includes non-toxic raw materials, synthesis of the catalyst is economical, and thermal stability of the catalyst is excellent. It is useful for producing an ethylene homopolymer or copolymers of ethylene and α-olefins having various physical properties in commercial polymerization processes.

The invention is directed to mixtures of polysilanes macroscopically solid at ambient temperature wherein the individual components of the composition SinH2n and / or SinH2n+2 of which decompose before they are boiling at an applied process pressure and which are produced from the hydrogenation of plasmachemically generated largely chlorinated polysilane mixtures. These mixtures of polysilanes are especially suited to be applied onto surfaces as solutions or dispersions and to obtain silicon-based structures or layers in subsequent process steps. Furthermore, they are especially safe in handling and can be additionally made up into transport forms in suitable transport containers.

The present invention relates to chalcone and chalcone derivatives and analogs which are useful as angiogenesis inhibitors. The present compounds, which are inexpensive to synthesize, exhibit unexpectedly good activity as angiogenesis inhibitors. The present invention also relates to the use of chalcone and its analogs as antitumor / anticancer agents and to treat a number of conditions or disease states in which angiogenesis is a factor, incluidng angiongenic skin diseases such as psoriasis, acne, rosacea, warts, eczema, hemangiomas, lymphangiogenesis, among numerous others, as well as chronic inflammatory disease such as arthritis.

Small molecule, peptidic hepatocyte growth factors mimics, which act as both mimetics and antagonists, have been generated. These molecules have been shown or predicted to have therapeutic potential for numerous pathologies including dementia (e.g. Alzheimer's) and Parkinson's disease.

The present invention relates to solenopsin A and its analogs for use as angiogenesis inhibitors. The present compounds unexpectedly exhibit good activity as angiogenesis inhibitors, which find use as antitumor / anticancer agents as well as to treat a number of conditions or disease states in which angiogenesis is a factor.

A vaccine is described which provides protection against a broad spectrum of viral strains, including but not limited to influenza A strains such as H1N1, H3N2, and H5N1. Embodiments of the present invention offer a number of advantages over conventional vaccine, in that they are cheaper to synthesize, more stable, easily scalable, and amenable to further genetic manipulation. Most importantly, certain embodiments of the present invention contemplate features, including but not limited to endosomal targeting, which result in a more robust immune response.

The purpose of the present invention is to develop and provide a nucleic acid molecule that can specifically and efficiently inhibit the activity of a target RNAi molecule and can be produced safely at a low cost. Provided is a nucleic acid molecule for inhibiting the activity of a target RNAi molecule. The nucleic acid molecule comprises a single-stranded nucleic acid moiety that contains one unmodified DNA region composed of a nucleotide sequence completely or sufficiently complementary to a nucleotide sequence of a functional strand having the activity in the target RNAi molecule and a double-stranded nucleic acid moiety to be linked to at least one of the 5′-end and the 3′-end of the single-stranded nucleic acid moiety.

A process performs solid phase synthesis of halogenated derivatives of fluorescein, and includes reacting fluorescein with a halide MX, wherein M is an alkali metal and X is a halogen, and Oxone(R) ( 2 KHSO5.KHSO4.K2SO4), at a temperature higher than or equal to 150° C. A structure uses a halogenated derivative of fluorescein selected from the group consisting of 2',4',5'-trichlorofluorescein, 2',4',5',7'-tetrachlorofluorescein, 4',5'-diiodofluorescein diacetate and 2',4',5'-triiodofluorescein as electro-bistable material in a non-volatile memory device.

The invention is directed to mixtures of polysilanes macroscopically solid at ambient temperature wherein the individual components of the composition SinH2n and / or SinH2n+2 of which decompose before they are boiling at an applied process pressure and which are produced from the hydrogenation of plasmachemically generated largely chlorinated polysilane mixtures. These mixtures of polysilanes are especially suited to be applied onto surfaces as solutions or dispersions and to obtain silicon-based structures or layers in subsequent process steps. Furthermore, they are especially safe in handling and can be additionally made up into transport forms in suitable transport containers.

The invention provides a Fe-doped Ni-MOF nanosheet as well as a preparation method and application thereof, and belongs to the technical field of electrochemical material preparation. The method comprises the following steps that: S1, terephthalic acid and soluble iron salt are fully dissolved in a solvent to obtain a solution B, wherein the mass ratio of the terephthalic acid to the soluble ferric salt is 1: (0.1-0.3); and S2, a NiCo-LDH nanosheet material taking foamed nickel as a substrate and the solution B obtained in the step S1 are put into a closed container, then solvothermal high-pressure reaction is carried out at 100-120 DEG C, and after the reaction is completed, filtering and drying are performed to obtain the Fe-Ni-MOF nanosheet. The electro-catalyst of the Fe-Ni-MOF layered nanosheet structure, which is low in price and excellent in electro-catalytic performance, is synthesized by a method of combining a technology of creating a high-temperature and high-pressure environment through a solvothermal method and a metal ion synergistic effect, and the method is simple and convenient to operate.

The invention relates to a silicone composition comprising components bearing ≡SiH / ≡SiOH groups, which can be polymerized / cross-linked by means of a dehydrogenative condensation reaction in the presence of a carbene-type catalyst in solution.

Use of a water-soluble paramagnetic substance to reduce the relaxation time of a coolant and corresponding method The invention relates to the use of a water-soluble paramagnetic substance, in particular a magnetic resonance contrast medium, to reduce the magnetic resonance relaxation time of a coolant for magnetic resonance systems. Furthermore the invention relates to a corresponding method for reducing the magnetic resonance relaxation time of a coolant.

The invention relates to the technical field of sewage treatment, and particularly discloses an efficient sewage treatment precipitant and a preparation method thereof. The precipitant is prepared from poly(diallyldimethylammonium chloride), a sodium hydroxyethyl cellulose aqueous solution and a sodium silicate aqueous solution, wherein the mass ratio of sodium hydroxyethyl cellulose to sodium silicate is 1:8-1:10, and the mass ratio of poly(diallyldimethylammonium chloride) to sodium hydroxyethyl cellulose is 1:1.7-1:2. The precipitant has the characteristics of larger flocs, lower dosage, notoxicity, lower synthesis price and higher precipitation efficiency.

The invention belongs to the technical field of fine chemical synthesis and particularly relates to a novel composite phosphonium salt as well as a preparation method and an antibacterial application thereof. The novel composite phosphonium salt adopts a molecular structure shown in the general formula represented in the specification, wherein R is selected from one of Cl, Br and NO2 groups. The novel composite phosphonium salt has good stability, excellent antibacterial performance and long bacteriostasis duration; the preparation method comprises steps of synthesis of brominated substituted benzyl triphenylphosphine, synthesis of an antibacterial complex, crystallization and the like, the operation is simple and controllable, large-scale instruments and equipment are not required, and the production cost is reduced remarkably.

The present inventio, relating to the field of biomatrix materials, discloses a preparation method and an application of cholesterol-carboxymethyl chitosan derivative materials, to solve the problems in the prior art of high synthesis price, natural degradation incapability, shortage of induction release function, shortage of targeting and slow release properties and poor compatibility. The preparation method comprises: (1) conducting carboxymethylation reaction on collagen on the condition that phthalic anhydride protects -NH2 of collagen C2 to synthesize O-carboxymethyl chitosan; (2) synthesizing cholesterol-carboxymethyl chitosan derivative materials through the esterification reaction of cholesterol and -COOH on carboxymethyl chitosan C6. The cholesterol-carboxymethyl chitosan derivative materials can be used to develop high efficiency and low residue green and environment-friendly nanocapsule slow release antimicrobial pesticide new dosage forms, and can prolong the validity period of the pesticide action, reduce the application amount of pestisides, and achieve high-efficiency pestiside utilization and environment protection.

The invention relates to the use of a water-soluble paramagnetic substance, in particular a magnetic resonance contrast medium, to reduce the magnetic resonance relaxation time of a coolant for magnetic resonance systems. Furthermore the invention relates to a corresponding method for reducing the magnetic resonance relaxation time of a coolant.

The invention relates to the field of organic photoelectric materials, and specifically discloses a coordination compound and a preparation method thereof, a phosphorescent material, an organic electroluminescent device, a display screen and a solar cell, wherein the coordination compound has the following structure defined in the specification. According to the invention, the coordination compound of the embodiments has good luminous efficiency; by selecting the ligand of the specific heterocyclic ring to combine, the wavelength of the coordination compound is adjusted, so that the organic electroluminescent device prepared from the obtained coordination compound has increased luminous efficiency and long service life; and the preparation method of the embodiments has advantages of low synthesis price and low synthesis process requirements, is suitable for industrial production, and solves the problem of insufficient luminous efficiency of the existing phosphorescent material.