The invention discloses a logistics transportation supervision system based on internet of things and cloud computing, which is composed of a transportation equipment supervision device, a personnel information supervision device, a logistics information supervision device and a logistics transportation supervision center, wherein the transportation equipment supervision device comprises a wireless communication module, a smoke sensor, a temperature and humidity sensor, an analog-digital converter, a signal conditioning circuit, a microprocessor module, a camera, an alarm and a power supply; the personnel information supervision device comprises a wireless communication module, a radio frequency recognizer, a microprocessor module, a camera, an alarm and a power supply; the logistics information supervision device comprises a wireless communication module, a radio frequency recognizer, a microprocessor module, an information positioning module and a power supply; and the logistics transportation supervision center comprises a wireless repeater, a cloud server and a central supervision device. The logistics transportation supervision system based on internet of things and cloud computing has the advantages of simple structure, informatization, network, cloud storage and computing, and high-efficiency real-time monitoring and safety management.