The invention discloses an orthopedic perforating device capable of precisely positioning. The orthopedic perforating device comprises a base, a power interface, a control switch and an operation panel are successively arranged on the front face of the base from right to left, a working table is arranged at the upper end of the base, a movable device is arranged at the middle of the upper end of the working table, a fixed base is arranged at the upper end of the movable device, a fixed sleeve matched with the fixed base is arranged at the upper end of the fixed base, a vertical column is arranged at the upper end of the base and disposed at one side of the working table, a crossbar is arranged at one side of the upper end of the vertical column, the crossbar is sleeved with a first slidingsleeve, the lower end of the first sliding sleeve is fixedly connected with the upper end of a vertical rod, the vertical rod is sleeved with a second sliding sleeve, a fixed base is arranged at thelower end of the vertical rod, a first rotating shaft is arranged at one side of the second sliding sleeve, and one end, away from the second sliding sleeve, of the first rotating shaft is movably connected with one end of a connection plate. The orthopedic perforating device has the advantages of being high in work efficiency, simple in operation, accurate in positioning, and safe and high-efficiency in perforation assisted treatment recovery of orthopedic patients, the degree of work difficulty of medical staffs is reduced, and the comfort of the patients is fully guaranteed.