The invention relates to the field of
traditional Chinese medicine preparation detection, in particular to a quality detection method of cough syrup for children. The quality detection method comprises the following steps: diluting a sample to be detected with
methanol, and filling into a liquid chromatograph for detection, and comparing an obtained chromatogram with a reference
fingerprint chromatogram so as to judge the quality of the sample to be detected, wherein the detection conditions of the liquid chromatograph are as follows: octadecylsilane chemically bonded silica is adopted as a filling agent,
acetonitrile is adopted as a flow phase A, a 1%
acetic acid solution is adopted as a flow phase B, the above components are eluted according to specific programs in a gradient manner, the
wavelength is 252-256 nm, the flowing speed is 0.8-0.9 ml / min, the
column temperature is 29-31 DEG C, and the number of theoretical plates is no less than 3000 according to the peak of
ammonium glycyrrhetate. As multiple influence factors are controlled, the quality detection method of cough syrup for children, which is provided by the invention, is stable, reliable and good in
repeatability, achieves the purpose of controlling the quality by virtue of
fingerprint chromatogram detection, and meanwhile is significant for ensuring the consistency of quality of each batch of products.