The invention provides an automatic leakage monitoring and repair system for a chemical plant device. The system comprises a seal point database, a working condition database, an expert knowledge subsystem, a leakage risk database, an automatic monitoring and evaluation subsystem and a repair task management subsystem, wherein the repair task management subsystem receives a task instruction, transmits the task instruction to a corresponding repair worker, and after a repair task is completed, sends a task complete instruction to the automatic monitoring and evaluation subsystem around a device corresponding to the repair task; the automatic monitoring and evaluation subsystem acquires monitoring data of a surrounding environment of the device, and automatically estimates a fugitive emission amount of the device area; if the fugitive emission amount exceeds a normal value, a new seal point repair task is further increased; and if the estimated emission amount is smaller than the normal value, there is no serious leakage point. The system reduces the leakage risk, effectively reduces the emission, realizes all-weather real-time online monitoring, and timely generates a repair task to remind an enterprise of quick repair.