10 results about "Graphene field effect transistors" patented technology

The application discloses a kind of Micro&Mini-LED architecture and its manufacturing method, including SiO2 layer, the bottom of the SiO2 layer is provided with Gate gate layer, the top of SiO2 layer is provided with a layer of graphene layer, one end of the graphene layer is provided with Source&Drain electrode and N-type electrode, the top of graphene layer is provided with a layer of N-type GaN layer, and N-type GaN layer extends to N-type electrode, the outside of Source&Drain electrode is provided with a layer of PMMA film layer, and PMMA film layer extends to graphene layer between Source&Drain electrode and N-type electrode, and is fixed by high temperature pyrolysis method on overflow method glass substrate and attached graphene film, and utilize graphene film as graphene field effect transistor to compose Micro-LED drive circuit, simultaneously, utilize PMMA material film formation to protect graphene layer, to prevent ultraviolet light exposure and etching to graphene cause damage, directly epitaxial growth GaN on graphene layer can realize the purpose of epitaxial LED chip on glass substrate.

Two-dimensional atomically thin heterostructure graphene field effect transistors (2D-HGFETs) are described in which a graphene conductive channel is encapsulated within highly insulating hexagonal boron nitride (hBN) layers with one dimensional metal edge contacts. The hBN layers comprise 10B or 11B that is isotopically pure. The 2D-HGFETS have demonstrated effects of remote interfacial phonons at the graphene / hBN interfaces when operated at elevated temperatures that impacts positively the transistor's performance including 1 / ƒnoise.

Provided are electronic biosensors based on graphene field effect transistors that utilize engineered hairpin probe DNA that allows for target recycling and hybridization chain reactions.

The invention relates to the field of biosensors, in particular to a biosensor and a preparation method and application thereof. The biosensor comprises a substrate and a graphene field effect transistor located on the substrate, the graphene field effect transistor comprises a source electrode, a drain electrode and a graphene channel connected with the source electrode and the drain electrode. And the alpha synuclein antibody is bonded on the surface of the graphene channel. According to the biosensor, the high-sensitivity G-FET sensor array is utilized, each detection unit is modified with an antibody, alpha-Syn detection under low concentration is achieved, and the problems of sensitivity reduction and false positive increase caused by non-specificity of a traditional amplification process are solved. Meanwhile, the technology can avoid the overlapping problem of multicolor fluorescence spectrums and realize specific sensing.

This invention provides a highly stable liquid-gate graphene field-effect transistor and its fabrication method, comprising: S1: hydrophobicating the substrate; S2: growing graphene by vapor deposition; S3: transferring the graphene onto the substrate; S4: drying, removing adhesive, cleaning, and removing impurities; S5: setting up a reaction tank and attaching the reaction tank above the graphene; S6: curing in an ultraviolet chamber to obtain the graphene field-effect transistor. This invention utilizes octadecyltrichlorosilane (OTS) to self-assemble on a glass substrate to form a hydrophobic film, effectively preventing the diffusion of liquid from the graphene surface to the space between the graphene and the substrate, thus overcoming the formation of a water film.

The invention belongs to the technical field of biomarker detection, and particularly relates to a suspended graphene field effect transistor, a preparation method thereof and application of the suspended graphene field effect transistor in a biosensor. The suspended graphene field effect transistor provided by the invention comprises a substrate, wherein a groove is formed in the upper surface of the substrate; the insulating layers are arranged on the upper surface, except for the groove, of the substrate, the side wall of the groove and the bottom surface of the groove, the electrode layers are arranged on the upper surfaces of the insulating layers and comprise source electrodes and drain electrodes, and the source electrodes and the drain electrodes are located on the upper surfaces of the insulating layers on the two sides of the groove respectively; and the single-layer graphene film is arranged on the upper surface of the electrode layer, covers the groove and is communicated with the source electrode and the drain electrode. The suspended graphene field effect transistor provided by the invention can realize miR-21 detection without marking, is high in detection sensitivity and low in detection limit, can realize miR-21 detection in a fly mole magnitude, and provides a technical approach for promoting early cancer diagnosis.

The present invention provides a stimulation and recording neural probe (100) at least comprising: a substrate (10); a stimulation and recording array (12), said stimulation and recording array (12) including at least one single-layer or double-layer solution-gated graphene field effect transistor (SG-GFET) (14) for recording brain signals of a patient, and at least one electrode (16) for applying electrical stimulation to a brain tissue and / or recording brain signals of the patient; and metal tracks (18, 20) for the at least one electrode (16) and the at least one single-layer or double layer SG-GFET (14), encapsulated in respective first and second encapsulation layers (22, 24). The invention further provides a method of manufacturing a stimulation and recording neural probe, such as the neural probe described above. Still further, the invention provides closed-loop system (200) for brain stimulation and recording comprising a control unit (202) and a stimulation unit (204), the stimulation unit (204) comprising at least one neural probe as described above.

Bifunctional graphene dielectrophoresis (DEP)-graphene field effect transistor (GFET) devices are provided. Aspects of the devices include: a graphene dielectrophoresis (DEP) component and a graphene field effect transistor (GFET) component, wherein the graphene DEP and GFET components are independently operable. Also provided are methods of evaluating a sample for the presence of an analyte, e.g., by introducing the sample into a bifunctional graphene dielectrophoresis (DEP)-graphene field effect transistor (GFET) device and obtaining a result from the device providing information as to whether the analyte is present in the sample. In addition, kits comprising the devices or systems described herein are provided. The devises, systems, methods and kits find use in a variety of different applications, including research and diagnostic applications.

Methods, systems and devices for detecting the presence of a pathogen, for example, a virus (e.g., SARS-CoV-2), or its molecular components, in health care-related samples and / or environmental samples are disclosed. An example system for improving detection of a pathogen includes biosensor device comprising a detection chip and at least one probe that specifically recognizes a pathogen, where the detection chip comprises a graphene field-effect transistor (FET) chip and the probe, which comprises an aptamer, specifically binds to a DNA, RNA, or protein associated with the pathogen.

The invention belongs to the technical field of biomedical detection, and discloses a preparation method of a microfluidic integrated graphene field effect transistor biosensor for rapid diagnosis of cytokine storm. The micro-fluidic integrated graphene field effect transistor biosensor is composed of a GFET sensing chip and a PMMA micro-fluidic module. Specific aptamers of cell factors such as TNF-alpha and IL-6 are fixed on the surface of the chip through the AL-BSA connecting layer, and the AL-BSA connecting layer serves as an anti-pollution layer, so that the anti-interference capability is remarkably improved. The microfluidic system is bonded on the sensing chip. According to the invention, synchronous, real-time and label-free detection of two cell factors is realized, the detection limit of TNF-alpha reaches 0.017 pg / mL, and the detection limit of IL-6 reaches 0.0158 pg / mL. The sensor has the advantages of high specificity, simplicity and convenience in operation and the like, and provides a reliable platform for bedside diagnosis of cytokine storm.