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75 results about "SKIN BENIGN NEOPLASM" patented technology

A neoplasm can be benign, potentially malignant, or malignant (cancer). Benign tumors include uterine fibroids, osteophytes and melanocytic nevi (skin moles). Potentially-malignant neoplasms include carcinoma in situ. Malignant neoplasms are commonly called cancer.

An anti-tumor compound and its preparation method, application, and pharmaceutical compositions

InactiveCN102924507AHighly directional (targeted) selectionOrganic active ingredientsGroup 5/15 element organic compoundsDiseaseEster prodrug
The present invention discloses an anti-tumor compound and its preparation method,application, and pharmaceutical compositions. The anti-tumor compound is a 4 - nitro-substituted benzyl group ifosfamide ester prodrug thereof, or pharmaceuticallysalt, or solvate thereof of the structure of formula I. The structure of formula I. The present invention has the following advantage of being used for the treatment or prevention of mammalian tumor-related diseases, such as leukemia, hemangioma, glioma, Kaposi's sarcoma, ovarian cancer, breast cancer, lung cancer, pancreatic cancer, lymphoma, prostate, colon and skin tumors and their complications.
Owner:ANHUI SIWEI PHARMA

Pharmaceutical composition for the management of tumors

The present invention relates to the effect of naturally occurring compounds on tumor development. As an example of proof, we used low; non-toxic doses of three compound e.g. Calcium D-glucarate, a naturally occurring Ca++ salt of D-glucaric acid; Nicotinamide (NA), a naturally occurring vitamin and butyric acid (BA), a naturally occurring saturated short chain fatty acid. 7,12 dimethylbenzanthracene (DMBA), which is a very potent skin carcinogen and is an environmental pollutant, was used for skin tumor development. Experiment was performed upto 30 weeks. All the above-mentioned compounds were used either alone or concomitantly any two or all the three. In the positive control group 100% tumorigenesis was attained in 28 weeks, use of single compound led to the inhibition of DMBA induced tumorigenesis between 33 to 47%, use of two compounds resulted in the 73 to 80% reduction in tumorigenesis but the concomitant use of three compounds resulted into 100% inhibition of tumor development at the end of 30 weeks. This led us to conclude that the concomitant use of Cag, NA and BA in combination of two is useful for preventing skin tumor develoment for a sort or long period of time. But the concomitant use of all the three compounds, as described, exhibited the perfect synergistic effect in preventing the tumor development completely. This strategy should be equally effective in the management of benign and possibly malignant tumor in any organ caused by any mean.
Owner:COUNCIL OF SCI & IND RES

Magnetic resonance imaging cancer probe and methods of use

InactiveUS20190053760A1Higher magnetic resonance sensitivityHigh sensitivityAcupunctureSurgeryAbnormal tissue growthChemical treatment
A magnetic resonance spectroscopy and imaging device and method of use for accurately delineating the lateral extent and depth of a skin tumor. The device includes a radiofrequency tuned circuit with an antenna in the shape of an acupuncture needle that is positionally-controlled using a mechanical actuator to provide high-contrast spatial images of skin tumors with sub-millimeter lateral and depth resolution. The device is used by dermatologists to provide accurate spatial demarcations of skin tumors, which facilitate the complete excision of a tumor in the first pass of the Mohs micrographic surgical procedure. Different sizes and shapes of the needle antenna provide advantages for sensitivity, image resolution, and capabilities to impact treatments. A hollow needle antenna provides for a capability of the inventive device to affect treatment of a skin tumor by injecting a chemical agent while monitoring chemical and spatial aspects of the tumor, and by aspirating cancer tissue to remove the tumor and related chemical treatment agents.
Owner:GERALD II REX ERVIN

Compositions and methods for treating skin cancer associated diseases

The invention provides compositions and methods for treating skin cancer associated diseases. Specifically, the invention relates to topically administering a signaling pathway inhibitor or a related compound to treat pre-cancerous skin lesions, skin tumors, and their associated diseases or disorders.
Owner:THE TRUSTEES OF THE UNIV OF PENNSYLVANIA

Intelligent tracking method and system for skin tumor precise surgery based on machine vision

The invention discloses an intelligent tracking method and system for a skin tumor precise surgery based on machine vision. The method comprises the following steps of conducting full-process high-definition shooting on the extraction process of a subcutaneous tissue slice and the re-excision process of a corresponding area of the subcutaneous tissue slice, and transmitting a shot video to a visual computing unit in real time; detecting and tracing a surgical blade by the visual computing unit according to the shot video, wherein specifically, the central point of a movement trajectory of thesurgical blade is calculated, then a corresponding surgical area is marked, a re-excision area is matched with a subcutaneous tissue slice extraction area, and a matching result is transmitted to a human-machine interaction unit; the human-machine interaction unit displays the matching result of the visual computing unit to a user, and simultaneously receives an operation instruction of the user and transmits the instruction to the visual computing unit. By means of the intelligent tracking method and system, the subcutaneous tissue slice extraction area and the re-excision area are marked bytracking the movement trajectory of the surgical blade, and the system is expected to replace a human assistant in large-area skin tumor excision surgeries.
Owner:SOUTH CHINA UNIV OF TECH

Pharmaceutical composition for the management of tumors

The present invention relates to the effect of naturally occurring compounds on tumor development. As an example of proof, we used low; non-toxic doses of three compound e.g. Calcium D-glucarate, a naturally occurring Ca++ salt of D-glucaric acid; Nicotinamide (NA), a naturally occurring vitamin and butyric acid (BA), a naturally occurring saturated short chain fatty acid. 7,12 dimethylbenzanthracene (DMBA), which is a very potent skin carcinogen and is an environmental pollutant, was used for skin tumor development. Experiment was performed up to 30 weeks. All the above-mentioned compounds were used either alone or concomitantly any two or all the three. In the positive control group 100% tumorigenesis was attained in 28 weeks, use of single compound led to the inhibition of DMBA induced tumorigenesis between 33 to 47%, use of two compounds resulted in the 73 to 80% reduction in tumorigenesis but the concomitant use of three compounds resulted into 100% inhibition of tumor development at the end of 30 weeks. This led us to conclude that the concomitant use of Cag, NA and BA in combination of two is useful for preventing skin tumor development for a sort or long period of time. But the concomitant use of all the three compounds, as described, exhibited the perfect synergistic effect in preventing the tumor development completely. This strategy should be equally effective in the management of benign and possibly malignant tumor in any organ caused by any mean.
Owner:COUNCIL OF SCI & IND RES

Preparation for treating skin tumors and neoplasm and preparation method thereof

The invention relates to the preparation technology of drugs for treating skin tumors and neoplasm, and aims at providing a preparation for treating the skin tumors and neoplasm and a preparation method thereof. The preparation is an injection product for injection and comprises anatase TiO2-coated nano monocrystal lanthanum boride, gelatin and deionized water; physical and chemical properties ofthe anatase TiO2-coated nano monocrystal lanthanum boride are as follows: the color and density depend on a thickness of a anatase TiO2 coating layer, the color is pink or light purple, the anatase TiO2-coated nano monocrystal lanthanum boride is insoluble in water, and the density is 4.1 to 4.5 g / cm<3>. The main component anatase TiO2-coated nano monocrystal lanthanum boride of the injection is simple in synthetic process and suitable for the industrialized mass production. By adopting the preparation, the surface wound infection can be controlled, the wound can be promoted to be rapidly healed, and the wound can be prevented from being infected. The temperature of an affected part can rise to the gelling temperature of proteins by utilizing the sunlight, the tumor cells and neoplasm cells can be killed, and the treatment effect can be achieved. The preparation has no drug side effect, and is safe and convenient, capable of saving trouble and money, and wide in industrialized prospect.
Owner:ZHEJIANG UNIV

Non-destructive detection system and method for skin tumors on basis of frequency modulation excitation thermal map

The invention discloses a non-destructive detection system and method for skin tumors on the basis of a frequency modulation excitation thermal map. The system comprises a thermal infrared imager assembly, a thermal excitation source, a function signal generator, a light modulator and a data receiving and processing device; the thermal infrared imager assembly includes an infrared thermography head, and the thermal excitation source includes a halogen lamp head. The method includes the following steps of adjusting the position of the thermal infrared imager assembly; adjusting the focal lengthof the infrared thermography head until a clear infrared image is displayed; adjusting the thermal excitation source to converge lamp holder apertures in the thermal excitation source to a to-be-detected part; inputting and determining a frequency modulation signal in the data receiving and processing device, outputting the frequency modulation signal to the function signal generator and redetermining the frequency modulation signal in the function signal generator; turning on a halogen lamp assembly power source and collecting image data of the to-be-detected part. Compared with the prior art, the system and method in the scheme have the advantages that patients have no painful feeling in a diagnostic process, the detection cost is low, and a detection result is accurate and reliable.
Owner:HARBIN UNIV OF COMMERCE
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