The invention relates to the technical field of chemical engineering, and discloses spherical particles containing TiO2 purification factors. The spherical particles comprise the following raw materials in parts by weight: 100-200 parts of titanium sulfate, 50-100 parts of a reaction solvent, 10-20 parts of a surfactant, 20-30 parts of sulfuric acid and 40-60 parts of urea. The spherical particlescontaining the TiO2 purification factors are uniform in particle size distribution, are free of agglomeration or large particles, and have good dispersibility. When the TiO2-containing purification factors are illuminated in an application process, hydroxyl free radicals and superoxide ion free radicals generated on the surface have very strong oxidizing capacity. Reaction energy of the hydroxylfree radicals is 402.8 MJ/mol, and bonds such as C-C, C-H, C-N, C-O, N-H and the like in organic matter can be sufficiently destroyed, so that organic pollutants are completely oxidized into carbon dioxide and water under the action of hydroxyl free radicals and superoxide ion free radicals, main indoor pollutants such as hydrocarbons, benzene, formaldehyde, sulfides, ammonia and the like can be effectively removed, and the formaldehyde removal effect is excellent.