The invention discloses a numerical control processing method and device for a complex molded surface of a rotor blade of an air compressor. The processing method comprises the steps of clamping the blade, selecting a milling cutter, and determining the milling mode of the blade and the milling sequence of the blade, wherein the back end of the blade is clamped through tightening; the milling cutter adopts a cylindrical cutter; the milling mode of the blade is spiral surrounding milling; and the milling sequence of the blade is that firstly, the edge is cut, then, a blade body is milled, then, a margin plate is milled, and finally, a root is milled. According to the processing method, the deformation in processing is reduced, the geometric accuracy and positional accuracy of the blade are guaranteed, the service life of the cutter is prolonged, the integrity of the blade surface is improved, the processing efficiency is improved, and the problems of overcutting and disorder of a cutter path are solved.