41results about How to "Reduce residue levels" patented technology

Compositions and methods for conferring herbicide resistance or tolerance to plants, plant cells, tissues and seeds are provided. Compositions include transgenic plants, plant cells, tissues, and seeds that have been transformed with a nucleic acid molecule encoding a cytochrome P450 or variant thereof that confers herbicide resistance or tolerance, alone or in combination with one or more additional nucleic acid molecules encoding polypeptides that confer desirable traits. In particular, the cytochrome P450 or variant thereof confers resistance or tolerance to HPPD inhibitors, benzothiadiazinones, sulfonylureas, and other classes of herbicides. The additional polypeptide may also confer resistance or tolerance to an herbicide, including HPPD inhibitors and other herbicides. Methods are also provided for the production and use of the herbicide resistant or tolerant plants, plant cells, tissues and seeds of the invention.

A disinfectant treatment for self-contained potable water systems. A lamp or lamps within the interior of at least one component system in which water is resident. During operation of the system. As the water tank, water heater, water filter, or other component which holds a volume of water. By putting a radioactive and a microbial effect in response to exposure to UV radiation may be formed of the vessel or other component. The radioactive material may be tin dioxide, titanium dioxide, or other material that produces hydroxyl ions in response to UV exposure. The hydroxyl ions flow from the vessel or other component into the piping and other components so as to attack / inhibit microbial action throughout the system. The lamps are mounted within quartz sleeves for immersion in water or other components. The quartz sleeves to prevent vibration damage. May also be used to of the system so as to prevent friction freeze damage.

A Pseudo-Random Phase Modulation (PRPM) multiple-input-multiple-output (MIMO) radar system suitable for use on an automated vehicle includes a first transmit-antenna that transmits a first transmit-signal generated by a first PRPM-code, a second transmit-antenna that transmits a second transmit-signal generated by a second PRPM-code, a receive-antenna used to detect a first reflected-signal arising from the first transmit-signal and a second reflected-signal arising from the second transmit-signal, and a controller. The controller is in communication with the receive-antenna and is operable to generate the first PRPM-code and the second PRPM-code. The controller is configured to generate a first sub-channel-output based on a down-converted-signal from the receive-antenna and the first PRPM-code, generate a second sub-channel-output based on the down-converted-signal from the receive-antenna and the second PRPM-code, determine a first residue-signal based on the second sub-channel-output, and determine a first residue-removed-signal by subtracting the first residue-signal from the first sub-channel-output.

A UV disinfectant system for treatment of water resident in a vessel. One or more UV lamps are mounted within the interior of the vessel so as to expose the water stored therein. The vessel may be, for example, a water tank, water heater, water filter or other component which holds a volume of water. A layer of photoreactive material may be formed on an inside surface of a wall of the vessel so as to be exposed to the UV radiation from the lamp. The photoreactive material may be tin dioxide, titanium dioxide, or other material that produces hydroxyl ions in response to UV exposure. The hydroxyl ions flow from the vessel into the piping and other components of the system so as to inhibit microbial action therein. The UV lamps may be mounted in quartz sleeves that surround the lamps for immersion in water and that are supported to protect the sleeves and lamps from vibration damage. The system may also be used to prevent freeze damage to the vessel and water system.

Processes and apparati are provided for separating molecules of interest from a mixture by depth filtration (DF). The DF of the invention is useful in the clarification and processing of various feedstreams for the removal of a molecule of interest. According to a preferred embodiment, a transgenic milk feedstream is stabilized and particulate matter such as fat, casein miscelles and bacteria are removed. An aseptic filtration step was also developed to remove any bacteria remaining in a clarified transgenic milk feedstream.

A continuous online process for rejuvenating whole stream of contaminated lean sulfolane in an extraction system is provided. In particular, a rejuvenator is installed in the solvent circulation loop to remove the contaminants continuously to keep the solvent clean, effective and less corrosive. Specifically, the rejuvenator comprises a high pressure vessel with a removable cover and a round rack with vertical stainless steel tubes fitted in the high pressure vessel. A magnetic bar is placed in each stainless steel tube. A screen cylinder is installed inside the ring of stainless steel tubes. As the contaminated sulfolane is passed through the rejuvenator, the rejuvenator picks up its contaminants. The rejuvenator can be dissembled to remove the contaminants periodically. The rejuvenator is characterized by simple in construction, reliable in operation, and low in operation and maintenance costs. With this rejuvenator, the extraction system can be operated at high efficiency and high capacity without the dreaded corrosion.

Methods for preparing microparticles having reduced residual solvent levels. Microparticles are contacted with a non-aqueous washing system to reduce the level of residual solvent in the microparticles. Preferred non-aqueous washing systems include 100% ethanol and a blend of ethanol and heptane. A solvent blend of a hardening solvent and a washing solvent can be used to harden and wash microparticles in a single step, thereby eliminating the need for a post-hardening wash step.

The present invention concerns methods for treating or preventing neurological disorders characterized by dysfunction of nicotine acetylcholine receptors by co-administration of metanicotine and at least one compound which exhibits antagonist activity, or both agonistic and antagonist activity, toward one or more nicotinic acetylcholine receptor subtypes. The subject invention, in another aspect, pertains to pharmaceutical compositions containing metanicotine and at least one compound which exhibits antagonistic activity, or both agonistic and antagonistic activity, toward one or more nicotinic acetylcholine receptor subtypes.

Processes and apparati are provided for separating molecules of interest from a mixture by depth filtration (DF). The DF of the invention is useful in the clarification and processing of various feedstreams for the removal of a molecule of interest. According to a preferred embodiment, a transgenic milk feedstream is stabilized and particulate matter such as fat, casein miscelles and bacteria are removed. An aseptic filtration step was also developed to remove any bacteria remaining in a clarified transgenic milk feedstream.

Compositions and methods for conferring herbicide resistance or tolerance to plants, plant cells, tissues and seeds are provided. Compositions include transgenic plants, plant cells, tissues, and seeds that have been transformed with a nucleic acid molecule encoding a cytochrome P450 or variant thereof that confers herbicide resistance or tolerance, alone or in combination with one or more additional nucleic acid molecules encoding polypeptides that confer desirable traits. In particular, the cytochrome P450 or variant thereof confers resistance or tolerance to HPPD inhibitors, benzothiadiazinones, sulfonylureas, and other classes of herbicides. The additional polypeptide may also confer resistance or tolerance to an herbicide, including HPPD inhibitors and other herbicides. Methods are also provided for the production and use of the herbicide resistant or tolerant plants, plant cells, tissues and seeds of the invention.

Methods of forming compositions for the sustained release of water soluble active agents, including biologically active polypeptides and products produced by the process are described. Improved product characteristics and ease of scale-up can be achieved using a novel coacervation process wherein at least one coacervation agent is added to the mixture comprising the active agent and the polymer in at least two distinct stages.

A Pseudo-Random Phase Modulation (PRPM) multiple-input-multiple-output (MIMO) radar system suitable for use on an automated vehicle includes a first transmit-antenna that transmits a first transmit-signal generated by a first PRPM-code, a second transmit-antenna that transmits a second transmit-signal generated by a second PRPM-code, a receive-antenna used to detect a first reflected-signal arising from the first transmit-signal and a second reflected-signal arising from the second transmit-signal, and a controller. The controller is in communication with the receive-antenna and is operable to generate the first PRPM-code and the second PRPM-code. The controller is configured to generate a first sub-channel-output based on a down-converted-signal from the receive-antenna and the first PRPM-code, generate a second sub-channel-output based on the down-converted-signal from the receive-antenna and the second PRPM-code, determine a first residue-signal based on the second sub-channel-output, and determine a first residue-removed-signal by subtracting the first residue-signal from the first sub-channel-output.

The invention relates to methods and systems for selective removal of catalyst residue from a depolymerization product stream without a water quench, as well as methods and systems for subsequent recovery of residual linear oligomer. The substantially metal-free and substantially water-free residual oligomer byproduct can then be advantageously used as recyclate in a process for preparing MPO. For example, the residual oligomer recyclate can be used as a reactant in the polymerization and subsequent depolymerization (cyclization) of low-acid polyester to form MPO.

A continuous, preferably counter-current, extraction process that can be used to significantly reduce the concentrations of residual monomers, residual catalyst, undesired solvents, and other impurities in polymer compositions. The invention is particularly beneficial for extracting residual monomers and other impurities from viscous, sticky polymer solutions, such as solutions of PSAs and low cohesive strength polymer compositions that phase change during extraction (i.e., change from liquid to solid, or precipitate), in a continuous manner. The polymer composition can be extruded into an extraction solvent as fibers in a vertical extraction column, under conditions such that at least a portion of an impurity is extracted from the polymer into the extraction solvent.

A continuous online process for rejuvenating whole stream of contaminated lean sulfolane in an extraction system is provided. A rejuvenator is installed in the solvent circulation loop to remove the contaminants continuously to keep the solvent clean, effective and less corrosive. The rejuvenator includes a high pressure vessel with a removable cover and a round rack with vertical stainless steel tubes fitted in the high pressure vessel. A magnetic bar is placed in each stainless steel tube. A screen cylinder is installed outside the ring of stainless steel tubes. As the contaminated sulfolane is passed through the rejuvenator, the rejuvenator picks up contaminants. The rejuvenator can be dissembled to remove the contaminants periodically. The rejuvenator is simple in construction, reliable in operation, and low in operation and maintenance costs. With this rejuvenator, the extraction system operates at high efficiency and high capacity without the dreaded corrosion.

The present invention provides methods of monitoring Aβ-directed immunotherapy. The methods involve administering a PET ligand that binds to amyloid deposits and detecting the PET ligand in the brain to provide an indication of the level and / or distribution of amyloid deposits. Surprisingly, the data in the present application show that a statistically significant reduction in amyloid deposits occurs early and consistently among patients following initiation of treatment before statistically significant effects of most if not all other markers are detectable. In consequence, the present methods allow early detection of whether a patient is responding to the Aβ-directed immunotherapy and if necessary adjustment of the immunotherapy regime.

The invention discloses an artichoke foliage spraying fertilizer. The artichoke foliage spraying fertilizer comprises nutrient elements, plant growth regulators and fungicides, wherein the nutrient elements include the following components at a mass ratio: 40-55g of urea, 15-20g of potassium dihydrogen phosphate, 5-8g of magnesium sulfate, 10-15g of potassium sulfate, 1-3g of ferrous sulfate, 1-3g of copper sulfate, 1-3g of zinc sulfate, 1-3g of manganese sulfate, 1-3g of boric acid and 1-3g of ammonium molybdate; the plant growth regulators include the following components: 10-15g of uniconazole, 0.01-0.05g of brassin and 0.02-0.05g of sodium nitrophenolate; the fungicides include 10-15g of cymoxanil and 15-20g of dimethomorph mancozeb. The components of the nutrient element are weighted according to the weight ratio and dissolved in 1000g of water and then the plant growth regulators and fungicides are added, mixed and dissolved to obtain a solution. The solution is diluted by 1000-1500 times and used as the artichoke foliage spraying fertilizer. Due to adoption of the artichoke foliage spraying fertilizer disclosed by the invention, the diseases and insect pests can effectively be prevented, the foliage spraying fertilizer is not easily enriched and concentrated in other organisms and the food chain, the residual level of the foliage spraying fertilizer is low and safe to the human and animals, the artichoke product can maintain a high quality, and after the foliage spraying fertilizer is sprayed on the artichoke, the growth and development of the artichoke are promoted and both yield and income are increased.

The invention relates to a preparation method of crosslinked sodium hyaluronate gel with ultralow crosslinking agent residual quantity and high viscosity, which comprises the following steps: S1, swelling the gel formed by crosslinking with a buffer solution, and preparing gel particles with proper particle size by using a high-speed dispersion machine; S2, adding dimethyl sulfoxide for washing, so that the unreacted cross-linking agent is eluted from the interior of the gel; S3, removing the dimethyl sulfoxide by adopting ultrafiltration; and S4, collecting a sample, and filling the sample into a filling and sealing injector. The preparation method is simple, the contact area of the gel and the washing filtrate can be effectively increased, and the uncrosslinked crosslinking agent embedded in the gel can be effectively removed by using the dimethyl sulfoxide which is a special organic solvent, so that the residual level of the crosslinking agent is far lower than that of the crosslinking agent prepared by the conventional preparation method.

The invention relates to a new radix salviae milliorrhizae extract and preparation thereof. The preparation method of the radix salviae milliorrhizae extract disclosed by the invention comprises the following steps: (1) extracting a radix salviae milliorrhizae medicinal material by using lower alcohol, filtering the obtained product so as to obtain alcohol extracting liquid, and taking herb residues A for standby application; (2) adding water into the herb residues A to extract, filtering the obtained product so as to obtain water extracting liquid, and removing herb residues B; (3) respectively cooling and standing the alcohol extracting liquid and the water extracting liquid, and respectively sucking supernatants as an alcohol extracting supernatant and a water extracting supernatant; (4) concentrating the water extracting supernatant so as to obtain a water extracting concentrated solution; (5) gradually adding the water extracting concentrated solution into the alcohol extracting supernatant, and concentrating the obtained mixture, so that a mixed concentrated solution is obtained; and (6) adding purified water into the mixed concentrated solution, concentrating the obtained mixture until a certain concentration proportion is achieved, and collecting paste, so that the radix salviae milliorrhizae extract is obtained.

There is a need for odorless rubbery polymers that offer high heat resistance, ultraviolet light resistance and low fogging characteristics. For instance, rubbery polymers of this type are needed by the automotive and construction industries. The deodorized rubbery polymers of this invention are of particular value because they can be blended with polyvinyl chloride to make leathery compositions having good heat and ultraviolet light resistance. The present invention more specifically discloses a process for preparing a deodorized rubbery polymer which comprises the steps of (1) polymerizing in a first stage (a) butyl acrylate, (b) at least one member selected from the group consisting of methyl methacrylate, ethyl methacrylate, methyl acrylate and ethyl acrylate, (c) acrylonitrile and (d) a crosslinking agent under emulsion polymerization conditions to produce a seed polymer containing latex, wherein said polymerization is initiated with a redox initiator system, wherein the redox initiator system is comprised of a free radical generator and a reducing agent; (2) adding (a) styrene, (b) additional acrylonitrile, (c) additional crosslinking agent and (d) additional free radical generator to the seed polymer containing latex under emulsion polymerization conditions which result in the formation of an emulsion containing the rubbery polymer; and (3) recovering the rubbery polymer from the emulsion containing the rubbery polymer.

Disclosed herein are viral vector production systems secreting nuclease for degradation of residual nucleic acid during viral vector production and methods of the same. Such a viral vector production system comprises a viral vector production cell comprising nucleic acid sequences encoding: 1) viral vector components; and 2) a nuclease, wherein the nuclease is expressed in the production cell and secreted in cell culture thereby degrading residual nucleic acid during viral vector production. Another such viral vector production system comprises 1) a viral vector production cell comprising nucleic acid sequences encoding viral vector components; and 2) a nuclease helper cell comprising a nucleic acid sequence encoding a nuclease, wherein the nuclease is expressed and secreted in co-culture of the production cell of 1) and the helper cell of 2), thereby degrading residual nucleic acid during viral vector production.

The invention relates to methods and systems for preparing macrocyclic polyester oligomer (MPO) directly from monomer via heterogeneous catalysis, rather than by depolymerizing a polyester. For example, in an exemplary embodiment, cyclic poly(butylene terephthalate) (cPBT) is produced by reacting butanediol (BDO) and dimethylterephthalate (DMT) in an organic solvent—for example, ortho-dichlorobenzene (oDCB). The mixture flows over (or otherwise contacts) the catalyst-coated fiberglass or silica gel, e.g., which is packed in a column or bed. MPO is produced in the reaction mixture, while residual linears and catalyst residue remain in the column / bed.

The present invention relates to a method for endotoxin removal from a sample comprising the following steps: combining the sample comprising one or more target molecule(s) with a chromatography media comprising beads having an inner porous core functionalized with ligands capable of binding endotoxin and an outer porous layer without functional groups and a pore size small enough to exclude the target molecule from the inner core; and collecting the sample from the media, wherein the sample comprises an endotoxin level which is at least 75% less, preferably 90% less, than before the removal and the yield of the target molecule is at least 75%.

A method for producing ketimine structure-containing alkoxysilane comprising reacting amino-functional alkoxysilane with a monocarbonyl compound by heating and azeotropically distilling off the produced water together with the monocarbonyl compound to yield ketimine structure-containing alkoxysilane, characterized by introducing additional monocarbonyl compound at the time of the azeotropic distillation of the produced water together with the monocarbonyl compound.

The present invention relates to a method for endotoxin removal from a sample comprising the following steps: combining the sample comprising one or more target molecule(s) with a chromatography media comprising beads having an inner porous core functionalized with ligands capable of binding endotoxin and an outer porous layer without functional groups and a pore size small enough to exclude the target molecule from the inner core; and collecting the sample from the media, wherein the sample comprises an endotoxin level which is at least 75% less, preferably 90% less, than before the removal and the yield of the target molecule is at least 75%.

The invention discloses a portable on-site air quality detector for environmental protection engineering construction, and relates to the technical field of air quality detectors. The detector includes a body, a control panel is fixedly arranged on the front face of the body, a temperature and humidity sensing area and an air inlet are fixedly formed in the top of the body, a display screen is fixedly arranged on the top of the front face of the body, a film is fixedly arranged on the front face of the display screen, and handrails are fixedly arranged on the two sides of the body. The hand of people can be protected by arranging a rubber sleeve, the air quality detector is prevented from being separated from the hand of people under the condition of strong wind, the film can prevent the display screen from being obviously abraded, data observation is clear, and the sliding block and the through groove which are meshed can assist in operating the dustproof net cover. The dustproof effect of the air quality detector is enhanced, operation of people is simplified, it is ensured that the air quality detector can work for a long time in the severe environment of a construction site, and the working performance of the air quality detector is improved.

Compositions and methods for conferring herbicide resistance or tolerance to plants, plant cells, tissues and seeds are provided. Compositions include transgenic plants, plant cells, tissues, and seeds that have been transformed with a nucleic acid molecule encoding a cytochrome P450 or variant thereof that confers herbicide resistance or tolerance, alone or in combination with one or more additional nucleic acid molecules encoding polypeptides that confer desirable traits. In particular, the cytochrome P450 or variant thereof confers resistance or tolerance to HPPD inhibitors, benzothiadiazinones, sulfonylureas, and other classes of herbicides. The additional polypeptide may also confer resistance or tolerance to an herbicide, including HPPD inhibitors and other herbicides. Methods are also provided for the production and use of the herbicide resistant or tolerant plants, plant cells, tissues and seeds of the invention.

The invention discloses an organic medicinal fertilizer with antibacterial and anthelmintic activities and a preparation method thereof. The active organic fertilizer contains 10-20 parts of Aconitum, 5-10 parts of Liwu, 4-8 parts of Artemisia chinensis, 10-15 parts of chamaejasma, 20-30 parts of Oxytropis, 2-3 parts of Drunken Horse Grass, and 5- 10 parts, 3-8 parts of Artemisia chrysanthemum stems, leaves, seeds, 50-60 parts of mushroom dregs, 10-20 parts of cottonseed meal, 5-10 parts of rice husks, crush the raw materials to replenish water, and after solid material microwave technology treatment, add According to 80g / T to 120g / T of active biological complex bacteria for composting and fermentation, the active biological complex bacteria are prepared by directly mixing Bacillus jelly-like, Bacillus megaterium, Bacillus subtilis, Glomus moses and Glomus terrestriale Antibacterial active biological organic fertilizer. The organic medicinal fertilizer provided by the invention contains antibacterial and anthelmintic components and an organic medicinal fertilizer with active organisms, and has wide application value.

The present invention relates to use of certain chain transfer agents to control molecular weight of addition mass polymerization of certain polycycloolefinic monomers. More specifically, the present invention relates to use of a series of substituted bicycloalkenes as chain transfer agents in the addition mass polymerization of a series of functionalized norbornene-type monomers. This invention also relates to compositions containing bicycloalkenes as chain transfer agents in forming “in mold” polycycloolefinic polymers by addition mass polymerization.

A rotary table device used for producing microdroplets from a liquid material and a device for producing microspheres are provided. The rotary table device has a rotary table structure the center of which is provided with a cup container and a driver thereof. At least two dish-shaped rotary table layers are embedded outside the cup container in order, with each dish-shaped rotary table layer beingprovided with a corresponding driver. A power unit below the cup container is started, a material solution in the cup container passes through the cup opening under the function of high-speed centrifugal force and hits the surface of an outer dish-shaped rotary table under functions of centrifugal force and impact force to form microdroplets; the formed microdroplets move to the edge of the rotary table and hit the surface of an outer dish-shaped rotary table having a larger inner diameter; after two or more times, the microdroplets move to the edge of the outer dish-shaped rotary table having the largest inner diameter, fly out of the rotary table and gradually cure to form microspheres; and then the dried microspheres are collected by a collector below the rotary table device.