44results about How to "Stable dose" patented technology

Disclosed are bioluminescent bioreporter integrated circuit devices that detect selected analytes in fluids when implanted in the body of an animal. The device comprises a bioreporter that has been genetically engineered to contain a nucleic acid segment that comprises a cis-activating response element that is responsive to the selected substance operably linked to a gene encoding a bioluminescent reporter polypeptide. In preferred embodiments, the target analyte is glucose, glucagons, or insulin. Exposure of the bioreporter to the target substance causes the response element to up-regulate the nucleic acid sequence encoding the reporter polypeptide to produce a luminescent response that is detected and quantitated. In illustrative embodiments, the bioreporter device is encapsulated on an integrated circuit that is capable of detecting the emitted light, processing the resultant signal, and then remotely reporting the results. Also disclosed are controlled drug delivery systems capable of being directly or indirectly controlled by the detection device that provide drugs such as insulin to the animal in reponse to the amount of target analyte present in the body fluids.

A dosing dispenser for dosing at least two components, wherein the dosing dispenser has a reservoir with at least two containers, which can be combined to form the reservoir and each of which can receive one component wherein each container has at least one engagement element at least in the area facing the bottom side of the container, the at least one engagement element having at least one projecting element and at least one corresponding recessed element, wherein the containers can be combined to form the reservoir by inserting the projecting elements of each container into the recessed elements of the respective other container.

Stable unit dose compositions with high water content are provided. Such unit dose compositions include an aqueous composition having a water activity of from about 0.65 to about 0.95 and a water-soluble container formed from a water-soluble or water-dispersible film material. In one embodiment, the aqueous composition includes water in an amount of 25% to 70% by weight, a surfactant system, and a water binding agent. The surfactant system may include: (1) a linear alkylbenzene sulfonate (LAS) and/or an alcohol ethoxylsulfate (AES), (2) a non-ionic surfactant, and (3) a fatty acid. The unit dose compositions can prevent the enclosed liquid detergent composition with a high level of water content from dissolving or pre-maturely dispersing the water-soluble container.

This invention relates to analogues of auristatins, in particular monomethyl auristatin F (MMAF), as cytotoxic agents, conjugates of such cytotoxic agents with a cell-binding agent, the preparation and the therapeutic uses of these cytotoxic agents and conjugates thereof to arrest or retard abnormal cell growth and /or proliferation.

Stable unit dose compositions with high water content are provided. Such unit dose compositions include an aqueous composition having a water activity of from about 0.60 to about 0.95 and a water-soluble container formed from a water-soluble or water-dispersible film material. In one embodiment, the aqueous composition includes water in an amount of 20% to 70% by weight, a structured surfactant system which is in the form of a lamellar structure, and a salt which promotes the formation of the lamellar structure. The surfactant system may include: (1) a linear alkylbenzene sulfonate (LAS) and/or an alcohol ethoxylsulfate (AES), (2) a non-ionic surfactant, and (3) a fatty acid. The unit dose compositions can prevent the enclosed liquid detergent composition with a high level of water content from dissolving or pre-maturely dispersing the water-soluble container due to the lamellar structure of the composition.

The purpose of the invention is to provide a Pudilan children's antiviral oral pellet gel and a preparation method thereof. The preparation method comprises the following steps: adopting a gel matrix, extracting Radix Scutellariae, Herba Taraxaci, Corydalis bungeana Turcz. and isatis root, preparing pellets by using extracted effective components, and uniformly dispersing the pellets in a gel. The prepared gel can be a solid gel, a semisolid gel or a xerogel. The method effectively covers the bad smell of medicines, solves the mouthfeel problem of the medicines, and allows the sweet oral pellet gel loved by children to be prepared, and the sweet and smooth mouthfeel of the oral pellet gel makes children easily take the medicine. Traditional Chinese medicines are combined with the gel dosage form to improve the children's administration long-term single dosage form, and the oral pellet gel has the efficacies of heat clearing, detoxification, antibiosis and inflammation prevention, and also has the advantages of high content of the effective component, small administrating dosage, stable preparation and good curative effect.

Stable unit dose detergent pacs are provided which are less prone to leakage or breakage and more aesthetically pleasing during handling. The unit dose pacs include a water-soluble container formed from a water-soluble or water-dispersible film and a wash composition encapsulated in the container. According to one embodiment, the wash composition includes an anionic surfactant present at from about 2% to about 35%, a non-ionic surfactant present at from about 2% to about 30%, and a solvent system present at from about 37.5% to about 80%, characterized in that the solvent system is composed of water and a single non-aqueous solvent only, or composed of water, a single non-aqueous solvent, and a residual solvent (less than 5%) only.

The present invention uses the oleanolic acid extracted from ligustrum fruit and zymolyzed dried powder made up by using silkworm chrysalis as main raw material, and adds the auxiliary materials of excipient and vitamins and utilizes a certain preparation process to obtain the invented liver-protecting functional food.

The invention discloses a liver-protecting functional food and a preparation method thereof. The liver-protecting functional food is prepared by using oleanolic acid extracted from ligustrum fruit and polysaccharide extracted from poria cocos and lentinula edodes as main raw materials, and by adding the auxiliary materials of excipient and vitamins. The liver-protecting functional food has effective components with definite structure, exact liver protecting effect, stable dosage and preparation form, and obvious effect of preventing and treating liver disease. According to the invention, the functional food can not only reduce the contents of MDA and TG in liver, has the function of protecting liver, is safe and non-toxic, and has no any side effects for long term taking.

A photolithography apparatus is constructed comprising an exposure light source that emits light with a wavelength of 400 nm or less as the exposure light, a reticle with a pattern original image formed therein, an illumination optical system that irradiates light outputted from the exposure light source onto the reticle, a projection optical system that projects the pattern image outputted from the reticle onto a photosensitive plate and an alignment system that positions the reticle and the photosensitive plate. At least some of the synthetic silica glass members composing the illumination optical system, the synthetic silica glass members composing the projection optical system and the reticle consist of synthetic silica glass members which, upon 1x104 pulse irradiation with an ArF excimer laser at an energy density from 0.1 muJ/cm2.p to 200 mJ/cm2.p, have a loss factor of no greater than 0.0050 cm-1 at 193.4 nm measured after irradiation, a hydrogen molecule concentration of from 1x1016 molecules/cm3 to 2x1018 molecules/cm3 and a loss factor of no greater than 0.0020 cm-1 before ultraviolet irradiation.

The invention discloses a feedback control method and system for an electronic accelerator irradiation system. The control method includes steps that (1), electrons are collected by an electron collector; (2), the aggregated power is amplified and adjusted to become a voltage signal of 0-10v; (3), an electron beam of 0-60mA outputted by an electron accelerator is proportionally adjusted to correspond to the 0-10v voltage signal; (4), the 0-10v voltage signal is transmitted to an industrial computer through a PLC AD analog module; and (5), the digital signal is calibrated and compared by the industrial computer, and equipment is controlled. The electronic collector of the control system is electrically connected with an electronic modulator through a power transmission line and a current limiting resistor, the electronic modulator is electrically connected with the PLC AD analog module through an optical isolator, and the PLC AD analog module is electrically connected with a PLC and theelectron accelerator. The method and the system are advantaged in that beam intensity can be accurately monitored and controlled, and stability and accuracy of the quality of irradiated products canbe greatly improved.

The present invention relates to a chewing gum formulation that serves as a means for awakening human consciousness and mindfulness to the sensorial subtleties, which in turn strengthens sovereignty such that overall psycho-spirituality is enhanced. More particularly, this invention relates to a dietary supplement consisting of the botanical plant Salvia divinorum as the source substance, including Salvinorin Alpha (A) as its primary active constituent, which is precisely extracted from S. divinorum to achieve a consistent dosing regimen predetermined for standardized efficacies.

The invention provides a single-photon 6MeV medical low-energy standing-wave accelerating tube, comprising a cavity chain body, wherein two ends of the cavity chain body are respectively connected with an electron gun and a target body; the side face of the cavity chain body is fixedly connected with a rectangular waveguide; the rectangular waveguide is fixedly connected with a microwave input window and a sputtering ion pump; the electron gun is a grid-control triode electron gun; in comparison with a diode electron gun, the grid-control triode electron gun is additionally provided with a grid; the grid can be used for better controlling beams and fine-tuning the X-ray dosage rate and energy, so that the electron beams can reach a stable state instantly and fast hit the target body, therefore X-rays are generated. The cavity chain body is an accelerating cavity chain consisting of 6-7 accelerating cavities with a beam aperture of 4-6 mm and a coupling cavity; the length of the cavity chain body is 27-33 cm; and according to the accelerating tube manufactured based on the design, the dose can reach the stable state in the beam outgoing moment.

The invention discloses a medical 'zedoary oil' and a manufacturing method for its micro capsule, the zedoary oil is acquired by confecting the beta-elemene, zedoary alcohol, curdione according to a fixed proportion, compared with natural zedoay oil, its effective ingredients content are high, and in virtue of the cooperation among the three, thus it has higher functions for resisting tumor, bacteria, and virusl; the producing method for mciro capsule is: because of increasing the even process, and through controlling the inner circulation in the even process, the particle size of the capsule is controllable between 50nm and 500nm, it can acquire the micro capsule with the uniform particle size, its irregularity is not more than plus and minus 5 nm.

The invention relates to a full-automatic dosing system for electroplating sewage treatment equipment. The full-automatic dosing system comprises a first dosing system for roughly adjusting a dose, a second dosing system for finely adjusting the dose, and a dosing control system for controlling the dose and dosing speed of the first and second dosing systems; the first dosing system and the second dosing system are respectively communicated with a wastewater pipeline for conveying wastewater; and the wastewater pipeline communicated with the second dosing system is positioned at downstream of the wastewater pipeline communicated with the first dosing system. Through the two dosing systems, full-automatic dosing system automatically adds agents into the wastewater, can effectively stabilize the dose of the agents and reduce the fluctuation of the dose, effectively controls the use cost of the agents, and is safe, simple and convenient.

The invention discloses an integrated field emission X-ray source, comprising a vacuum container, an anode target installed in the vacuum container and an electron gun, wherein the electron gun comprises an emission cathode and a grid, the emission cathode and the anode target are respectively installed at opposite ends in the vacuum container, and the grid is installed between the emission cathode and the anode target; Also included is a feedback control circuit, A feedback control circuit includes an anode current sampling module, scan memory module, A non-linear regulation control module and a gate voltage input module, The input of the anode current sampling module is connected to the anode target electrode, the input of the non-linear regulation control module is connected to the anode current sampling module and the scanning memory module, respectively, and the output of the non-linear regulation control module is connected to the gate electrode through the gate voltage input module. The invention makes the current fluctuation of the X-ray source small, and has excellent X-ray stable emission performance.

The invention discloses a self-coated non-vascular orifice insertion tube, and belongs to the technical field of medical instruments. The self-coated non-vascular orifice insertion tube comprises a non-vascular orifice insertion tube, and is characterized in that the right end of an outer cylinder body sleeves the outer wall of the left end of an inner cylinder body, an annular piston is arrangedin an annular cavity of the inner cylinder body, the annular piston is connected with the right end of a sleeve, and the left end of the sleeve is connected with an annular top plate; a first compression spring is arranged between the annular piston and the left end wall of the inner cylinder body, the inner wall of the sleeve is provided with a plurality of fixing grooves, grooves corresponding to the fixing grooves are formed in the lower end wall of the annular cavity of the inner cylinder body, a ratchet bar is fixedly arranged in each fixing groove, the outer wall of a positioning wheel is provided with a plurality of arch-shaped protrusions arranged uniformly in a circumference, an arc-shaped groove is formed between every two arc-shaped projections, and the inner side end of a guiding ball abuts in an arc-shaped groove of the positioning wheel. Compared with the prior art, the self-coated non-vascular orifice insertion tube has the advantages of simple structure and reasonable design.