This invention provides a coherent anti-Stokes
Raman microscope system, its driving method, and its microscopic apparatus. The coherent anti-Stokes
Raman microscope system includes: a
femtosecond laser front-end module, a dual-
wavelength module, a
pulse broadening and amplification module, a time
delay module, a spectral broadening and filtering module, a
second harmonic generation module, a
dispersion compensation module, and a
microscope module. The self-
phase modulation spectral selection (SESS) driven coherent anti-Stokes
Raman microscope system of this invention uses a self-
phase modulation spectral selection (SESS) method to convert a 1550 nm pulse
wavelength to 1600 nm. Through a frequency doubling
crystal, a
second harmonic generation process is achieved, converting the 1600 nm pulse
wavelength to 800 nm, thus realizing coherent anti-Stokes Raman
microscopy imaging, i.e., selective imaging of various
biological tissue components. Compared with other
wavelength conversion methods, the device is simple, has high conversion efficiency, is tunable, and has strong
scalability.