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Coherent anti-stokes raman microscopy system, its driving method and microscopy apparatus

ActiveCN119394998BEnable selective imagingImprove conversion efficiency
This invention provides a coherent anti-Stokes Raman microscope system, its driving method, and its microscopic apparatus. The coherent anti-Stokes Raman microscope system includes: a femtosecond laser front-end module, a dual-wavelength module, a pulse broadening and amplification module, a time delay module, a spectral broadening and filtering module, a second harmonic generation module, a dispersion compensation module, and a microscope module. The self-phase modulation spectral selection (SESS) driven coherent anti-Stokes Raman microscope system of this invention uses a self-phase modulation spectral selection (SESS) method to convert a 1550 nm pulse wavelength to 1600 nm. Through a frequency doubling crystal, a second harmonic generation process is achieved, converting the 1600 nm pulse wavelength to 800 nm, thus realizing coherent anti-Stokes Raman microscopy imaging, i.e., selective imaging of various biological tissue components. Compared with other wavelength conversion methods, the device is simple, has high conversion efficiency, is tunable, and has strong scalability.
Owner:INSTITUTE OF PHYSICS CHINESE ACADEMY OF SCIENCES

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