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46 results about "Lactose intolerant" patented technology

Probiotic fermented milk suitable for people suffering from lactose intolerance and preparation method of probiotic fermented milk

The invention discloses probiotic fermented milk suitable for people suffering from lactose intolerance and a preparation method of the probiotic fermented milk, and belongs to the field of health-care foods. The preparation method comprises the following steps: cleaning and drying jerusalem artichoke stalks, crushing and sieving to obtain jerusalem artichoke stalk particles, heating and extracting the jerusalem artichoke stalk particles with distilled water, filtering, and concentrating to obtain an extract; carrying out silica gel column chromatography on the extract, eluting with ethyl acetate, collecting eluent, and carrying out rotary evaporation to obtain a jerusalem artichoke stem extract; mixing milk with the jerusalem artichoke stem extract, sterilizing, and adding a probiotic leavening agent for fermentation to obtain yoghourt after fermentation is finished; and adding inulin and fructo-oligosaccharide into the yoghourt, uniformly mixing, refrigerating, and performing after-ripening to obtain the probiotic fermented milk suitable for people suffering from lactose intolerance. The jerusalem artichoke is treated and fermented together with the milk, and then the inulin and the fructo-oligosaccharide are added, so that the activity of beta-galactosidase generated by probiotics is greatly improved, and adverse symptoms generated when L1 patients take milk products are remarkably relieved.
Owner:山东福乐维康生物科技有限公司

Trpv4 antagonist

The present invention relates to a novel compound useful as a TRPV4 antagonist, specifically the compound 1-(((5S,7R)-3-(5-cyclopropylpyrazin-2-yl)-7-hydroxy-2-oxo-1-oxa-3-azaspiro[4.5]decan-7-yl)methyl)-1H-benzo[d]imidazole-6-carbonitrile, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compound.The compound of the invention can be useful in the treatment of a disease state selected from: atherosclerosis, disorders related to vasogenic edema, postsurgical abdominal edema, ocular edema, cerebral edema, local and systemic edema, fluid retention, sepsis, hypertension, inflammation, bone related dysfunctions and congestive heart failure, pulmonary disorders, chronic obstructive pulmonary disorder, ventilator induced lung injury, high altitude induced pulmonary edema, acute respiratory distress syndrome, acute lung injury, pulmonary fibrosis, sinusitis / rhinitis, asthma, cough; including acute cough, sub-acute cough and chronic cough, pulmonary hypertension, overactive bladder, cystitis, pain, motor neuron disorders, genetic gain of function disorders, cardiovascular disease, renal dysfunction, stroke, glaucoma, retinopathy, endometriosis, pre-term labor, dermatitis, pruritus, pruritus in liver disease, diabetes, metabolic disorder, obesity, migraine, pancreatitis, tumor suppression, immunosuppression, osteoarthritis, crohn's disease, colitis, diarrhea, intestinal irregularity (hyperreactivity / hyporeactivity), fecal incontinence, irritable bowel syndrome (IBS), constipation, intestinal pain and cramping, celiac disease, lactose intolerance, and flatulence.
Owner:GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO 2) LTD
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