49 results about "Lactose intolerant" patented technology

Methods, compositions, and systems are provided for detecting one or more a gastrointestinal issues by characterizing the microbiome of an individual, monitoring such effects, and / or determining, displaying, or promoting a therapy for the gastrointestinal issue. Methods, compositions, and systems are also provided for generating and comparing microbiome composition and / or functional diversity datasets. Methods, compositions, and systems are also provided for generating a characterization model and / or therapy model for constipation issues, diarrhea issues, hemorrhoids issues, bloating issues, and lactose intolerance issues.

A “reverse isotope dilution assay” herein, wherein a pathway that produces a given metabolite is assayed by diluting a labelled metabolite produced by a second constitutive pathway. In one aspect, the invention relates to a method for monitoring lactose maldigestion or lactose intolerance in humans. Specifically, the method requires administering a reverse tracer of labeled glucose and unlabeled lactose to an individual and assessing labeled carbon dioxide in breath or blood. If the lactose is digested, the labeled CO2 produced by the labeled glucose is diluted by the metabolism of the lactose.

Compositions for ameliorating the symptoms associated with lactase deficiency, the composition including a lactose reduced dairy product, and an effective amount of a probiotic, a prebiotic, or a mixture thereof. The lactose reduced dairy product is selected from a fluid milk, a smoothie, a liquado, ice cream, yogurt, and a yogurt drink. Methods for treating lactose intolerance in a patient in need thereof, the method includes providing a composition having a lactose reduced dairy product, and an effective amount of a probiotic, a prebiotic, or a mixture thereof. The lactose reduced dairy product is selected from a fluid milk, a smoothie, a liquado, ice cream, yogurt, and a yogurt drink.

The invention relates to a low-lactose milk powder and a preparation method thereof. The lactose content of the low-lactose milk powder of the invention is 4.5-10%; the preparation method of the low-lactose milk powder includes that lactose enzyme is added into crude milk for hydrolysis after pasteurization on crude milk and before production burdening on the basis of the conventional production process. The invention adopts advanced biological enzymolysis technology, through researches on technological conditions of the steps of burdening, filtration, homogenizing, preheating and sterilization, evaporation concentration, spray drying, cooling, sieving, packaging and the like, a low lactose milk power is developed, the milk powder is full of nutriments, lactose hydrolysis rate can be above 70%, not only intolerance symptom of lactose intolerant people to lactose can be relived, but also the requirement of the lactose intolerant people on flavour and taste can be met.

The method for increasing lactose tolerance in subjects exhibiting lactose intolerance symptoms implements a protocol where the subjects ingest a gradually increasing amount of lactose containing product over a six week period. At various points during the six week period the subject ingests the lactose containing product once a day and then twice a day. The lactose containing product can be in liquid form, such as for example, milk, and is preferably in a powder form which is taken either by ingesting capsules having the lactose powder or in a granular form mixed with water or other non-lactose containing liquid. At the end of the six week period, the subject's tolerance for lactose containing products is substantially increased, with the potential of eliminating the subject's lactose intolerant behavior indefinitely.

The present invention discloses probiotics enriched crisp apple products and a preparation method thereof, and belongs to the technical field of agricultural product processing. Apples are used as raw materials, the apples are washed, the washed apples are blanched, a vacuum soaking method is used to enrich probiotics into apple tissues, and then a vacuum freeze-drying and vacuum microwave combined drying method is used to prepare the probiotics enriched crisp apple products. The method comprises the following steps: (1) raw material washing and blanching; (2) probiotic soaking liquid preparing; (3) vacuum soaking; and (4) vacuum freeze-drying and vacuum microwave combined drying. The prepared probiotics enriched fruit and vegetable crisp products are mellow in fruit fragrance, and crisp and tasty. The viable probiotic number can be maintained at 10<7> CFU / g at 25 DEG C for 90 days or more. The preparation method avoids the two major defects of high cholesterol risk of the probiotic fermented milk products and the non-consumption of lactose intolerant population, and the products combine health care and leisure, and have broad market prospects.

The invention discloses plant nutrient powder suitable for babies 12-24 months old. The plant nutrient powder comprises the following raw materials in parts by mass: 18-22 parts of rice, 4-6 parts of millet, 4-6 parts of glutinous millet, 4-6 parts of pearl barley, 4-6 parts of oat, 20-24 parts of isolated soy protein, 0.5-3.5 parts of fructooligosaccharide, 1.5-2.5 part of stachyose, 6-10 parts of apple powder, 6-10 parts of vegetable powder, 3-7 parts of honeysuckle extract, 1.5-2 parts of honey and 11-15 parts of plant. The plant nutrient powder disclosed by the invention is rich in various plant proteins, can prevent a baby from eating milk animal nutrition excessively, balance balanced diet, promote healthy growth of a baby and avoid allergy caused by animal proteins; moreover, since no lactose is in the formula of the plant nutrient powder, the baby can be prevented from having lactose intolerance.

The invention relates to a production method of high-protein milk and belongs to the field of dairy product processing. The production method includes: using raw milk to produce concentrated milk protein liquid, evenly mixing the raw milk with the concentrated milk protein liquid, performing pasteurization and cooling, adding lactase for enzymolysis, weighing and evenly mixing white granulated sugar and additives, performing shear thinning on the material obtained after the enzymolysis and the mixture of the white granulated sugar and the additives, evenly mixing, homogenizing, sterilizing and performing sterile filling. By the production method, the high-protein milk can be produced by using the liquid protein, and the produced high-protein milk is fresh, fine and smooth in taste, rich in nutrition, applicable to lactose-intolerant people, low in fat content, low in calorie value and healthy.

The invention provides a lactose-free infant formula food and a preparation method thereof. The preparation method disclosed by the invention comprises the following steps: adopting a dry-wet compounding process, namely producing vegetable fat powder by a wet process, and producing lactose-free whole milk powder by a lactose digestion process; performing dry mixing on the vegetable fat powder, thelactose-free whole milk powder, other main ingredients and auxiliary materials and bioactive substances, thereby obtaining the formula food suitable for lactose intolerant infants at an age of 0-12 months. According to the formula, the lactose is completely replaced with other carbohydrates, the lactose content of the product is less than 0.5wt%, and 1.8-2.2wt% of galactose having an important effect on brain development of the infants is remained. The protein in the formula is provided by lactoprotein, and the formula food is suitable to be eaten by the lactose intolerant infants so as to avoid lactose intolerance.

The invention relates to the technical field of food ingredients, specifically to a lactose-free infant formula milk powder for special medical use and a preparation method thereof. A special medical condition is primary or secondary lactose intolerant babies. The lactose-free infant formula milk powder mainly comprises the following ingredients (by weight): 35-70% of plant oil fatty powder, 1-10% of concentrated milk protein, 3-15% of separated whey protein, 20-50% of solid corn syrup powder, 0.1-5% of trace elements and 0.1-5% of vitamins, wherein sum of contents of the ingredients is no more than 100%, and content of lactose is less than 0.5g / 100g. The lactose-free infant formula milk powder contains 30 vitamins and trace elements which are essential to infants daily, linoleic acid, alpha-linolenic acid / aliphatic acid combination, DHA, AA and nucleotide, and lactose content meets requirements of GB25596-2010 on lactose content of lactose-free formula milk powder. In comparison with a common formula milk powder (containing lactose), the product meets health requirements of lactose intolerant lactose-free infants.

The invention provides lactose-intolerance fermented milk. The lactose-intolerance fermented milk is prepared by fermenting, by weight, 92.9874-99.994% of raw milk, 0-7% of sugar and 0.006-0.0126% of a fermentation agent; the fermentation agent comprises streptococcus thermophilus AIBI S 4.01 SWEET purchased from the Soyuz Nabob group. Lactase and a stabilizer are not added in the raw materials of the fermented milk, the lactose is degraded with special streptococcus thermophilus, and the fermented milk is refreshing in taste and delicate in tissue; the lactose content in the fermented milk is 0.014-0.5%, lactose-intolerance standard stipulated internationally is achieved, the problem about use of the fermented milk by lactose intolerant patients is solved, and the fermented milk in rich and full in nutrition and has the effect of immune disease prevention; during preparation, enzymolysis time of the lactase is omitted, no equipment and process is added, and production cycle of the fermented milk is short.

The invention provides methods and pharmaceutical compositions for treating symptoms associated with lactose intolerance and for overall improvement in gastrointestinal health. Described herein are methods and pharmaceutical compositions for improving overall gastrointestinal health or for decreasing symptoms of lactose intolerance by administering to subject in need thereof a pharmaceutical composition comprising a prebiotic, optionally in combination with effective amount of a probiotic microbe or microbes. The invention also provides diagnostic instruments and methods of diagnosing lactose intolerance using the diagnostic instruments.

A self-contained, portable H2 / CO2 (air) ratio apparatus has an exhaled breath system, an air analyzing chamber, a hydrogen concentration analyzer, a carbon dioxide (air) concentration analyzer, an air outlet, a computational analyzer and a display unit. The display unit can be a part of the self-contained, portable H2 / CO2 (air) ratio apparatus, remotely a part of the self-contained, portable H2 / CO2 (air) ratio apparatus, or combinations thereof. The apparatus can assist in the diagnosis of a neonatal patient developing necrotizing enterocolitis and / or lactose intolerance.

Provided is a method of preparing a high-purity galactooligosaccharide composition by fermentation of a low-purity galactooligosaccharide mixture with a yeast strain, Kluyveromyces lactis ATCC 8585. The high-purity galactooligosaccharide composition includes at least 99% of galactooligosaccharides selected from the group consisting of galactotriose, galactotetrose, galactooligosaccharides with five or more sugar units, and combinations thereof and lower than 1% of monosaccharides and disaccharides. Also provided is a high-purity galactooligosaccharide composition and applications thereof in regulating blood glucose level and improving gut microbiota. For example, the high-purity galactooligosaccharide composition may be used to manufacture food products, beverages, health food products, nutritional supplements, and pharmaceutical compositions for patients or pets afflicted with diabetes mellitus or lactose intolerance.

The invention provides lactose-free lipid-lowering milk and a production method thereof. The lactose-free lipid-lowering milk is prepared from a main material and auxiliary materials in the weight ratio being (90-98):(2-10), wherein the main material is lactose-free milk, the auxiliary materials comprise 50-80 parts by weight of hawthorn fruit powder, 10-30 parts by weight of cassia seed powder, 10-20 parts by weight of black fungus polysaccharides and 0.1-1 part by weight of phytosterol. During preparation, firstly, components of the auxiliary materials are mixed in proportion and then mixed with the lactose-free milk, the mixture is homogenized and sterilized, and the lactose-free lipid-lowering milk is obtained. According to the lactose-free lipid-lowering milk, various Chinese herbal medicine components perform a synergistic function and have a remarkable curative effect on hyperlipidemia; the content of lactose in the lactose-free milk is lower than 0.1%, and the lactose-free lipid-lowering milk is suitable for lactose-intolerant people; due to complete removal of lactose and monosaccharide, the lactose-free lipid-lowering milk is also suitable for people who have higher requirements for the content of sugar, such as people suffering from diabetes.

The invention relates to healthy food compositions with a gel or foam texture that have antioxidant properties, are rich in proteins, low-fat, lactose- and casein-free and easy-to-chew, comprising a neutral-flavored egg hydrolysate as a basic ingredient.These compositions are presented as an alternative to sweet and salty dishes using dairy products as a base because they have similar flavor, appearance and texture characteristics. These compositions are also presented as new foods that are particularly indicated for being consumed by people who are lactose intolerant or who have obesity issues.

The present invention relates to human milk oligosaccharides (HMOs) for use in the following, synthetic compositions comprising HMO for use in the following, and methods for prophylactically reducing the severity and / or incidence of gastrointestinal IBS symptoms in lactose intolerant IBS patients; reintroducing a lactose source into the diet of lactose intolerant IBS patients while prophylactically reducing the gastrointestinal IBS symptom severity and / or symptom incidence in IBS patients; and / or reducing the severity and / or incidence of non-gastrointestinal symptoms in lactose intolerant IBS patients.

The invention relates to a walnut calcium supplement effervescing preparation which is prepared from the following raw materials in parts by weight: 20-35 parts of walnut granules, 20-24 parts of ascorbic acid, 15-20 parts of calcium fumarate, 15-20 parts of calcium lactate and 15-20 parts of calcium gluconate and the like. The calcium supplement effervescing preparation provided by the invention contains multiple organic calcium and inorganic calcium and is more beneficial to absorption of calcium of human body, reduction of morbidity of osteoporosis and maintenance of hardness of skeleton and tooth, and the calcium supplement effervescing preparation can nourish brain. The calcium supplement effervescing preparation provided by the invention contains lactase and is especially applicable to people who suffer from lactose intolerance.

The invention discloses lactose-free micro-fermented cow milk and a preparation method thereof. The micro-fermented cow milk is prepared from the following raw materials in percentage by mass: 99.925 to 99.971 percent of raw milk, 0.008 to 0.012 percent of yeast, 0.001 to 0.003 percent of lactobacillus plantarum and 0.02 to 0.06 percent of lactase. The preparation method of the lactose-free micro-fermented cow milk comprises the following steps: S1, preheating raw milk, and degreasing to obtain skimmed milk and single cream; S2, sterilizing the skimmed milk in S1, adding yeast and lactase, heating, adding lactobacillus plantarum, and carrying out fermentation hydrolysis to obtain a fermentation hydrolysis feed liquid; and S3, sterilizing the single cream in the S1, adding the single cream into the fermentation hydrolysis feed liquid in the S2, preheating, carrying out sterile homogenization, cooling and filling to obtain the product. The micro-fermented milk disclosed by the invention does not contain lactose, is suitable for lactose intolerance consumer groups, and is good in flavor and taste.

The invention discloses a tablet formulation against lactose intolerance and alactasia and the preparation method. The formulation includes active ingredient lactase, excipient diluent agent, disintegrating agent, binder, wetting agent, glidant and lubricant. Among starch, microcrystalline cellulose, mannitol and pre-gelatinized starch, one ingredient or more than two ingredient compound can be chosen as diluent agent (filling agent); one or more ingredients can be chosen from carboxymethyl starch, crosslinking sodium carboxymethyl cellulose, crosslinking povidone, low-substituted hydroxypropyl cellulose, microcrystalline cellulose and pre-gelatinized starch as disintegrating agent; one ingredient can be chosen from povidone, starch pulp and any cellulose as binder; one ingredient can be chosen from micro-powder silica gel and talcum powder to be used as glidant; one ingredient can be chosen from magnesium stearate, calcium stearate, stearic acid, hydrogenated vegetable oil and carmowax as lubricant; one ingredient can be chosen from ethanol, water and ethanol water as wetting agent.

The invention aims at disclosing deep hydrolyzed protein formula powder and a preparation method thereof. The deep hydrolyzed protein formula powder is prepared from the following components in mass percent: 70-80% of vegetable fat powder, 10-20% of deep hydrolyzed protein powder, 1-5% of glucose syrup dry powder, 1-5% of a nutritional enhancer, 1-5% of fructo-oligosaccharide, 1-3% of arachidonicacid powder and 1-3% of docosahexaenoic acid powder. Compared with the prior art, the formula powder is reasonable in formulation, relieves complications such as infantile diarrhea, eczema and asthmacaused by milk protein allergy, and solves the problem of infantile diarrhea while solving protein allergy. For lactose intolerant people, the formula powder can be better digested and absorbed, and alleviate the problem of diarrhea in allergic people, achieving dual purposes. Addition of the nutritional enhancer ensures comprehensive and reasonable nutrition in the development stage of newborns,and meets the normal needs of physiology and life, thereby maintaining and improving the health level of the newborns. The formula powder is reasonable in design, easy to produce and convenient to control, and realizes the purposes of the formula powder.

The invention provides a composition for use in therapy of lactose intolerance or conditions arising from lactase deficiency, wherein the composition is a non-dairy solid dosage form comprising:(a) a lactase; and(b) one or more lactase-producing and / or lactase containing microorganisms selected from Lactobacillus delbrueckii ssp bulgaricus and Streptococcus thermophilus; wherein the lactase (a) is other than a lactase derived from the said one or more microorganisms (b); and wherein the one or more lactase-producing and / or lactase-containing microorganisms (b) are in dried form.Also provided are uncoated capsule and tablet compositions containing the lactase and the lactase-producing and / or lactase-containing microorganisms.

The invention provides a strawberry clavulanic acid milk beverage which comprises the following raw materials in parts by weight: 300-500 parts of raw goat milk, 25-40 parts of white granulated sugar, 0.04-1 part of acesulfame potassium, 5-9 parts of strawberry juice, 0.1-1 part of sodium citrate, 1-6 parts of lactic acid, 1.2-4 parts of citric acid, 0.5-7 parts of soluble dietary fiber, 0.01-0.08 part of salt, 0.05-1 part of broken pine pollen, 1.5-6 parts of stabilizer, 0.1-5 parts of sodium cyclamate, 0.1-0.6 part of potassium sorbate and 0.05-0.55 part of edible essence. The invention also provides a preparation method for the strawberry clavulanic acid milk beverage. The preparation method comprises the steps of reducing pressure, deodorizing and homogenizing. The strawberry clavulanic acid milk beverage prepared according to the method provided by the invention is low in lactose content, is capable of relieving the untoward effect to the lactose intolerant patient and meets the requirement of the lactose intolerant patient. The lactose content is 0.01-0.02% and is lower than that of the marketing milk beverage.

The invention discloses probiotic fermented milk suitable for people suffering from lactose intolerance and a preparation method of the probiotic fermented milk, and belongs to the field of health-care foods. The preparation method comprises the following steps: cleaning and drying jerusalem artichoke stalks, crushing and sieving to obtain jerusalem artichoke stalk particles, heating and extracting the jerusalem artichoke stalk particles with distilled water, filtering, and concentrating to obtain an extract; carrying out silica gel column chromatography on the extract, eluting with ethyl acetate, collecting eluent, and carrying out rotary evaporation to obtain a jerusalem artichoke stem extract; mixing milk with the jerusalem artichoke stem extract, sterilizing, and adding a probiotic leavening agent for fermentation to obtain yoghourt after fermentation is finished; and adding inulin and fructo-oligosaccharide into the yoghourt, uniformly mixing, refrigerating, and performing after-ripening to obtain the probiotic fermented milk suitable for people suffering from lactose intolerance. The jerusalem artichoke is treated and fermented together with the milk, and then the inulin and the fructo-oligosaccharide are added, so that the activity of beta-galactosidase generated by probiotics is greatly improved, and adverse symptoms generated when L1 patients take milk products are remarkably relieved.