54 results about "Squaraine dye" patented technology

The present invention relates to amphiphilic squaraine dyes of the general formula (1) as shown below Formula (1) wherein, R<1> = -(CH2-CH2-O)n-CH3, n = 4-8, or -(CH2)n-CO2X, n = 3-6, X = H, succinamide and R<2> = -CH3 or -(CH2-CH2-O)n-CH3, n = 4-8 and pharmaceutically acceptable derivatives thereof, for use as near infrared fluorescence probes in photodynamic diagnostic and biological, biochemical and industrial applications.

The invention relates to a preparation method of a tin indium sulfide / squaraine composite visible light catalyst. The preparation method comprises the following steps: preparing tin indium sulfide, synthesizing indole squaraine dyestuff and preparing the tin indium sulfide / squaraine composite visible light catalyst. The preparation method provided by the invention has the beneficial effects that the preparation method is relatively simple and preparation conditions are easy to control; the prepared tin indium sulfide / squaraine composite visible light catalyst is a green, environment-friendly and high-performance catalyst, has no pollution and has high catalysis efficiency and certain application value.

Photochemical acid progenitors in combination with dihydroperimidine squarylium dyes have been found to be particularly effective at generating acid upon irradiation with near-infrared radiation. It has been found that dihydroperimidine squarylium dyes that are particularly useful in this invention have an oxidation potential greater than about 0.5 V relative to SCE as measured in dichloromethane.

A squarylium dye represented by formula (1):wherein A1 and B1 each independently represents a ring structure, and R1 and R2 each independently represents a substituent having a carbon number of 1 to 12.

The invention relates to water-soluble near infrared luminescent quinoline squaraine dye, of which the molecular structural general formula is shown on the figure. The method for preparing the water-soluble near infrared luminescent quinoline squaraine dye comprises that: firstly, 2-methylquinoline is subjected to bromination, sulfonation, nitration and acylation and reacts with acetonitrile and iodo-acid or iodo-ester to generate quinoline quaternary ammonium salt; and secondly, the quinoline quaternary ammonium salt is mixed with squaric acid, and the mixture is subjected to azeotropic distillation and dehydration, vacuum distillation and silica gel column chromatography and recrystallization through ethanol to obtain the water-soluble quinoline squaraine dye. The dye is applied in the fields of development of novel medicines, fluorescence labeling, probes, biological immunoassay, biological immunodetection and the like. The fluorescence-emission wavelength of the water-soluble quinoline squaraine dye is near infrared, so that the water-soluble quinoline squaraine dye has superior penetrability on environments and biological tissues and reduces self absorption and background absorption, and the sensitivity of fluorescence analysis can reach 10<-10> mol / L. The preparation method is simple and easy, has low cost and good economic benefit and is suitable for industrialized production.

The invention belongs to the technical field of squaraine dyes, and particularly relates to an indole squaraine dye and a preparation method and application thereof. The provided indole squaraine dyehas a structural formula shown in the formula (I), wherein R is a phenyl, an anthryl or a pyrenyl. The indole squaraine dye has a high molar extinction coefficient in the near-infrared region, has strong absorption in the near-infrared region, has obvious effects in sensitized singlet oxygen, can be used as a triplet photosensitizer, has a good application prospect in the field of photodynamic therapy, and can solve the problem that the existing squaraine dye has low quantum yield of the singlet oxygen in photodynamic therapy.

The invention relates to synthesis of an amphiphilic indole squarylium cyanine dye and an application of the dye in the field of specific lysosome marking. In the invention, phenylhydrazine hydrochloride, of which a 4 position is substituted by bromine, hydrogen or methyl, is employed as a raw material to prepare the indole squarylium cyanine dye having the three substitutive groups and having carboxyl group functionalization, and then a condensation reaction between a carboxyl group and a primary amine is carried out to further introducing amino groups into the dye molecules. Ultraviolet absorption and fluorescent emission of the amphiphilic indole squarylium cyanine dye are both in near infrared region, so that interference due to background fluorescence in a bio-imaging process is reduced greatly. The dye is water-soluble so that the dye can be directly used in bio-imaging without any organic co-solvents, thereby achieving low bio-toxicity. The amino group in the dye is fully protonized under a lysosome acidic environment so that the electrostatic effect with lysosome membrane is more intensive. The dye can be used for marking the lysosome in living cells with marking time being capable of lasting for more than 48 h. It is the first time that the indole squarylium cyanine dye is applied in the field of lysosome marking.

The invention relates to a method for preparing a trapezoidal broadband absorption carbene squaraine dye with a one-step method. The method comprises the following steps of: fully mixing functional carbine, a squaric acid, a ligand and a solvent at the room temperature; undergoing a reflowing reaction at the temperature of 60-130 DEG C for 10-120 hours; and after the reaction, purifying to obtain the carbene squaraine dye, wherein the mass ratio of the functional carbine to the squaric acid is (20-10):(4-1). The preparation method provided by the invention is easy and practicable, has a good economic benefit, and is suitable for industrial production; and the carbene squaraine dye prepared with the method can be widely applied in the fields of nonlinear optics, photodynamics therapy, optical database storage, laser printing, biological probes, near infrared mapping, solar cells, and the like.

Provided are a squarylium dye having a carboxyindolenine structure and an N-alkyl substituent, and a photoelectric conversion element having high photoelectric conversion efficiency in a near-infrared region and a dye-sensitized solar cell, both of which are produced using the squarylium dye. The photoelectric conversion element or dye-sensitized solar cell uses a compound represented by the formula (1) as the squarylium dye. In the formula (1), R1 and R2 represent a substituted or unsubstituted C5 to C30 alkyl group; X represents C(CH3)2; and A and B represent a carboxy group.

Fluorescent cyanine and squaraine dyes are described that can be conjugated to analyte molecules of interest such as peptides, proteins, nucleic acids, RNA, DNA, carbohydrates, polymers aid small molecules via a sulfonyl or sulfonamide substituent. The new dyes are made via a novel cyanine dye activation procedure that converts the normally stable, water solubilizing sulfonate substituents into a reactive sulfonyl halides. The sulfonyl halides may be directly conjugated to analytes or can be further converted to more stable reactive sulfonamide handles or to water soluble sulfonamides. The general structure of the new dyes is given below where the central linker is an unsaturated carbon chain or an unsaturated chain containing a squaraine moiety.