56 results about "Stimulant drug" patented technology

This invention relates to a nutritional intervention composition for enhancing satiety prior to a meal and extending satiety after a meal. The nutritional intervention composition decreases food intake producing weight loss over time. The composition consists of Niacin, Vitamin B6, Calcium, Phosphorous, Magnesium, Chromium, Chitosan, Fenugreek, Ginseng, White willow bark, Garcinia cambogia, Aloe Vera gel powder, Momordica charantia, Griffonia simplicifolia, Lagerstroemia speciosa and Vanadyl sulfate. The invention does not require stimulants or anabolic ingredients. There are three phases of activity within the composition. One, enhanced satiety through elevated serotonin. Two, improved carbohydrate metabolism, reduced blood glucose and slowed gastric emptying. Three, enhanced fiber binding of lipids and excess bile acids.

A pharmaceutical composition comprising at least one of components (a) and at least one of components (b) shown in below: (a) a compound represented by the general formula (I) (wherein R1 represents a hydrogen atom or a hydroxyl group) or an acid addition salt or hydrate thereof; and (b) an ameliorant of cerebral circulation, a vasodilator, a cerebral protecting drug, an brain metabolic stimulants, an anticoagulant, an antiplatelet drug, a thrombolytic drug, an amelirant of psychiatric symptom, a antihypertensive drug, an antianginal drug, a diuretic, a cardiotonic, an antiarrhythmic drug, an antihyperlipidemic drug, an immunosuppressant, or a pharmaceutically acceptable salt (except the components shown in (a)). It is useful as a preventive or remedy for cerebrovascular disorders and cardiac diseases.

The invention provides a natural plant health care product capable of calming heart, refreshing mind, tonifying brain and improving intellectual development and a preparation method thereof. The health care product at least comprises the following raw materials in parts by weight: 20-200 parts of soybean, 20-200 parts of mung bean, 20-200 parts of wheat, 10-100 parts of Chinese dates, 10-100 parts of spina date seeds, 5-60 parts of lucid ganoderma and 5-30 parts of liquorice. The preparation method thereof comprises the following steps: washing the raw materials clean, denucleating, slicing, drying, heating slightly, crashing, poaching, filtering and concentrating; extracting with ethanol to obtain an extracting solution; and preparing the extracting solution into various preparations of the natural plant health care product. The health care product has the efficacies of calming the heart, tranquilizing the mind, nourishing the heart, refreshing the mind, tonifying the brain, improving the intellectual development, stabilizing emotion, replenishing heart and brain nutrition, improving and consolidating memory and the like, thus realizing the purposes of cheering spirits, concentrating attention and overcoming the difficulties and obstacles in sleep, learning and examinations caused by psychological, spiritual and physical problems; and the health care product does not contain any hormone and stimulant, and has no toxic and side effects and dependence.

The present disclosure provides oral drug dosage forms comprising: (a) an erodible non-stimulant material admixed with an ADHD non-stimulant; and (b) an erodible stimulant material admixed with an ADHD stimulant, wherein the erodible non-stimulant material admixed with the ADHD non-stimulant is embedded in a substrate material, and wherein upon exposure to gastrointestinal fluid the ADHD non-stimulant is released according to a desired non-stimulant release profile and the ADHD stimulant is released according to a desired stimulant release profile. In some embodiment, the ADHD non-stimulant is released according to a sustained release profile. In some embodiments, the ADHD stimulant is released according to an immediate release profile. The oral drug dosage forms of the present disclosure are useful for the treatment of attention deficit hyperactivity disorder (ADHD). Also provided herein are methods of designing and manufacturing the oral drug dosage forms described herein.

The invention discloses a quantum dot and immunochromatography test strip rapid detection method for beta-stimulant multiresidue. The detection method includes the steps that a quantum dot is coupled with beta-stimulant monoclonal antibody to obtain a quantum dot and beta-stimulant monoclonal antibody labeling complex which is namely a quantum dot fluorescence probe; after the labeling complex serving as the quantum dot fluorescence probe and a sample to be detected are mixed uniformly and incubated, and an immunochromatography test strip is used for detecting the beta-stimulant residue. Multiple beta-stimulant drugs can be screened fast, the detection method is simple, fast, accurate in result, high in sensitivity, low in prices and wide in application range and has excellent application and popularization prospects, and qualitative and quantitative determination can be carried out.

The polypeptides in the present invention possess the effects of promoting and inhibiting the secretion of prolactin, and are thus useful as drugs for the prevention and treatment of various diseases, in terms of prolactin secretion stimulants, which are associated with the secretion of prolactin, such as hypoovarianism, spermatic underdevelopment, menopausal symptoms, hypothyroidism, etc. The polypeptides are useful as drugs for the prevention and treatment of various diseases, in terms of prolactin secretion inhibitors, which are associated with the secretion of prolactin, such as pituitary tumor, diencephalon tumor, menstrual disorder, autoimmune diseases, prolactinoma, sterility, impotence, amenorrhea, lactorrhea, acromegaly, Chiari-Frommel syndrome, Argonz-del Castilo syndrome, Forbes-Albright syndrome, lymphoma, Sheehan's syndrome, spermatogenesis disorder, etc.

The invention discloses a method applicable to serum-free culture of mesenchymal stem cells. The method comprises a step of adding a stimulant drug thrombin into a base culture medium to stimulate mesenchymal stem cells to secrete endogenous fibronectin. The method disclosed by the invention is a method which is simple and convenient, low in cost and high in safety, effectively solves an adherence problem of the serum-free cultured mesenchymal stem cells, and also obviously promotes the mesenchymal stem cells to propagate in a serum-free culture medium at the same time. The method is applicable to serum-free culturing and propagating of clinical research-level mesenchymal stem cells.

The invention relates to a five-conjugate testing card for detecting beta-stimulant drugs and a preparation method thereof and belongs to the technical field of beta-adrenergic receptor stimulant detection. A test strip is arranged in a casing of the testing card which is composed of a polyvinyl chloride (PVC) glue board, a sample pad, a colloidal gold combination pad, a coated film and absorbent cotton. A colloidal gold film is a glass cellulose film which contains colloidal gold markers of a clenbuterol monoclonal antibody, a ractopamine monoclonal antibody, a salbutamol monoclonal antibody, a phenylethanolamine A monoclonal antibody and a terbutaline monoclonal antibody. The coated film is a nitrocellulose film, wherein five detection lines T and a quality control line C are arranged on the coated film, and the quality control line C is coated with a rabbit anti-mouse immunoglobulin G (IgG) antibody. The five-conjugate testing card can simultaneously detect out clenbuterol, ractopamine, salbutamol, phenylethanolamine A and terbutaline, and is simple, convenient and fast in method, and accurate in result.

The invention discloses a colloidal gold kit for detecting a beta-stimulant drug. The kit comprises reagent strips and colloidal-gold marker micropores, the reagent strip comprises a base plate, a chromatography membrane, a sample pad arranged at two ends of the chromatography membrane, and an absorbent pad are arranged on the base plate in order, a quality control line C and a detection line arearranged on the chromatography membrane, the line C is coated with a goat-anti-mouse IgG antibody, the detection line comprises a T1 line and a T2 line, the T1 line is a ractopamine detection line, and is coated with a ractopamine antigen, the T2 line is the salbutamol, clenbuterol, brombuterol, tulobuterol, mabuterol, terbutaline, cimbuterol, clorprenaline, and cimaterol detection line, the T2 line is coated with a beta-stimulant antigen, the line C, the T1 line, and the T2 line present three parallel bands which are vertical to a long phase of a test paper strip, the colloidal-gold marker micropores contains a colloidal gold-labeled beta-stimulant polyclonal antibody and a ractopamine monoclonal antibody, by aiming at special objects of raw milk and fresh milk, ten drugs can be detectedat one time, a detection scope is enlarged, leak detection can be prevented, sensitivity is high, and stability is good.

The invention provides a method for simple, rapid and inexpensive analysis of drugs such as nicotine and other drugs which are accumulated in biological samples of addictive drugger of tobacco, stimulant drug and the like. The method comprises the steps of introducing the biological sample into an injection needle, inserting the needle into an injector of a chromatograph and injecting a carrier into the needle to conduct chromatography treatment.

The invention provides a healthy product for relieving the physical fatigue and a preparation method thereof, and relates to an anti-fatigue healthy product and a processing process thereof. The healthy product is characterized by being prepared from the following components in parts by weight: 25-45 parts of ginseng extract, 100-200 parts of acanthopanax extract, 110-210 parts of polygonatum kingianum extract, 50-110 parts of cervus elaphus linnaeus powder, 10-30 parts of starch and 2-6 parts of magnesium stearate. The preparation method comprises the following steps: screening raw and auxiliary materials; weighing the materials; mixing the materials; filling capsules; radiating and sterilizing; and inspecting and sending into warehouse. The healthy product has the characteristics of small-dosage taking, quick response, good anti-fatigue effect, no stimulant and the like, is suitable for common people and athletes, and is a relatively ideal healthy product capable of relieving physical fatigue.

The invention relates to a traditional Chinese medicine extract and an application field thereof, and discloses application of a morinda officinalis extract in preparation of a skeletal muscle fatigueresisting agent. The skeletal muscle fatigue resisting agent comprises components of 0.1-2.5 mg/mL of the morinda officinalis extract, 6-7 mg/mL of NaCl, 0.13-0.15 mg/mL of KCl, 0.1-0.3 mg/mL of NaHCO3, 0.1-0.3 mg/mL of CaCl2, 0.01-0.02 mg/mL of NaH2PO4, 1-3 mg/mL of glucose and water. A traditional Chinese herbal medicine, namely, the morinda officinalis extract is used as the main component ofthe morinda officinalis extract, the time for skeletal muscle to reach the fatigue state can be prolonged, the fatigue resisting activity of the skeletal muscle can be effectively improved, besides, no stimulant is added, and the skeletal muscle fatigue resisting agent is a safe and efficient anti-fatigue drug.

The present invention relates to compositions and methods for treating neuropsychiatric disorders in vertebrates and humans. More specifically, the present invention provides for use of IRL-1620, an endothelin-B receptor agonist, in appropriate doses to be a neuroprotective and a neuroregenerative agent. Accordingly, in one aspect the disclosure provides a method of treating a neuropsychiatric disorder comprising administering to a patient in need thereof a therapeutically effective amount of an endothelin-B receptor agonist to treat the neuropsychiatric disorder. In some embodiments, the endothelin-B receptor agonist is co-administered with an additional agent to treat the neuropsychiatric disorder. In some embodiments, the additional agent is selected from the group consisting of an antidepressant, an anti-inflammatory agent, a CNS stimulant, a neuroleptic, and an anti-proliferative agent.

The invention relates to a detection method for detecting beta-receptor stimulant drugs in animal body fluid. The method comprises the steps of enabling animal body fluid to be detected to come into contact with acetonitrile, ethyl alcohol or a multiwalled carbon nanotube for the first time to obtain sample extraction liquid, enabling the sample extraction liquid to come into contact with chloroauric acid solution and cetyl trimethyl ammonium bromide solution in PBS (Phosphate Buffer Solution) for the first time to obtain a reaction mixture, incubating the reaction mixture for 4-12min at 60-100 DEG C and observing the color change of the reaction mixture. The invention also provides a detection kit for detecting beta-receptor stimulant drugs in animal body fluid. The method can conveniently and rapidly detect the beta-receptor stimulant drugs in animal body fluid.

Novel compounds, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the compounds are agonists and/or ligands of cannabinoid receptors and may be useful, inter alia, for treating and/or preventing pain, gastrointestinal disorders, genitourinary disorders, inflammation, glaucoma, auto-immune diseases, ischemic conditions, immune-related disorders, and neurodegenerative diseases, for providing cardioprotection against ischemic and reperfusion effects, for inducing apoptosis in malignant cells, and as an appetite stimulant.

The present invention relates to a thermo-responsive hydrogel polymer formulated with one or more active agents selected from the group consisting of menthol and menthone, wherein said active agents are effective in invigorating the user and/or effective in relieving fatigue.

The invention discloses a method for simultaneously and quantitatively detecting the contents of epinephrine, phenothiazine and atropine drugs in a sample. The method comprises the following steps oftaking a to-be-detected sample solution, detecting by the high performance liquid chromatography, and carrying out gradient elution by using a sodium heptanesulfonate solution as a mobile phase A andmethanol as a mobile phase B. According to the method, the sample is simple to prepare and operate, at most three or eight compounds can be detected at the same time, the separation condition betweenchromatographic peaks is good, and the method is suitable for detecting the content of epinephrine receptor stimulant drugs, phenothiazine drugs and atropine in food, drugs, blood products and the like.

The invention provides a method for detecting seven protein assimilation preparation stimulants in animal feed, which comprises the following steps of: adding an isotope internal standard intermediate solution, deionized water and dichloromethane into a sample for extraction, purifying a dichloromethane layer, blowing the obtained supernatant to be nearly dry, dissolving by using a mixed solution of acetonitrile, formic acid and water, carrying out vortex oscillation, filtering to obtain a to-be-detected solution, and determining by using a high performance liquid chromatography tandem mass spectrometer to obtain corresponding spectrogram information; determining the mixed standard working solution under the same condition, and comparing two groups of spectrogram information; and finally, selecting corresponding parameters from the content and the peak area of a to-be-detected component in the mixed standard working solution, the concentration and the peak area of an internal standard substance in the to-be-detected solution, the peak area of the to-be-detected component in the to-be-detected solution, the peak area and the concentration of an internal standard substance in the mixed standard working solution, the extraction volume, the sample weight, the extraction volume and the constant volume of a sample solution and the dilution ratio, and calculating the content of all stimulants by using an internal standard method and an external standard method.