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74 results about "Trans-resveratrol" patented technology

Resveratrol-Containing Compositions And Methods Of Use

A resveratrol-containing composition capable of providing a therapeutic benefit to a subject such as modulation of a biological activity, improving cell transplantation therapy, or improving macular degeneration or dystrophy treatments. The compositions comprise trans-resveratrol, a metal chelator, and one or more additional antioxidants such as phenolic antioxidants or vitamin D.
Owner:RESVERATROL PARTNERS

Dietary supplement system for multifunctional anti-aging management and method of use

A dietary supplement system includes a dietary supplement composition for oral administration by an individual in the morning, the composition, including (a) a telomere maintenance complex including: Purslane extract (aerial parts); Turmeric rhizome extract (95% curcuminoids); Quercetin dehydrate, Cayenne pepper fruit; Vanadium (as vanadyl sulfate); Fenugreek seed; Astragalus root extract, Omega fatty acid complex including linoleic acid; alpha-linolenic acid; oleic acid borage seed oil gamma-linolenic acid), evening primrose oil fish body oil (eicosapentaenoic acid; docosahexaenoic acid); (b) a calorie restriction mimetics and gene expression complex including Trans-resveratrol (from Polygonum cuspidatum root extract); Pterostilbene Fisetin 50% (Buxus microphlla Sieb (stem and leaf; Alpha lipoic acid, Coenzyme Q-10, Betaine HCl, Sulfur (from methylsulfonylmethane); L-Carnitine tartrate; L-Carnitine HCl, and (c) a free radical scavenger complex, including Green tea leaf extract catechin and polyphenols); Anthocyanins (from bilberry fruit and grape skin extracts).
Owner:LIFE SCI INT

Stereoselective route to produce tris-O-substituted-(E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene, an intermediate in the synthesis of trans-resveratrol

The present invention relates to a new stereoselective method for the preparation of tris-O-substituted-(E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene derivative of the formula (I) which is a key intermediate in the synthesis of trans-resveratrol (I, R2=R2=R3=H). The invention also provides a method for the exclusive synthesis of trans-isomer of compounds of formula (I) without any contamination of cis-isomer.
Owner:ORCHID CHEM & PHARM LTD

Resveratrol complex and process for the preperation

The present invention provides products having resveratrol with high water solubility and nutraceutical and / or phytotherapic compositions having said substances. The processes for obtaining them include the solubility increase of the polyphenol corresponding to a resveratrol compound, preferably trans-resveratrol in water, by its complexation with cyclodextrin under specific conditions that favor thermodynamic equilibrium. The products of the invention present high solubility and purity in aqueous medium, being, therefore, useful to prepare nutraceutical compositions (pharmaceutical and / or alimentary) with antioxidant, anti-inflammatory, antiviral, antidiabetics, cardioprotective, neuroprotective, chemoprotective activities; besides protecting against infections and ischemia, reducing obesity, and preventing aging. Phytotherapic compositions useful to the same therapeutical activities, prepared from the complex of resveratrol and cyclodextrin compound, preferably beta-cyclodextrin / trans-resveratrol, are also provided.
Owner:UNIAO BRASILEIRA DE EDUCACAO E ASSISTENCIA MANTENEDORA DA PUC RS

Composition comprising polyphenol

A food product comprising from 0.05 to 1 wt % of trans-resveratrol can advantageously be used to control blood pressure. Preferred food products are spreads or drinks.
Owner:CONOPCO INC D B A UNILEVER

Compositions Containing Resveratrol and Nucleotides

ActiveUS20130123207A1BiocideHydroxy compound active ingredientsNucleotideGamma-Tocotrienol
A resveratrol-containing composition capable of providing a therapeutic benefit to a subject such as modulation of a biological activity, improving cell transplantation therapy, or improving macular degeneration or dystrophy treatments. The compositions comprise trans-resveratrol, a metal chelator, one or more additional antioxidants such as quercetin, gamma-tocotrienol, or apple polyphenols, allicin, and nucleotides.
Owner:RESVERATROL PARTNERS

Process of obtainment of trans-resveratrol and/or emodin and nutraceuticcal compositions containing them

Processes for the separation and purification of polyphenol trans-resveratrol and / or anthraquinone emodin from Polygonum cuspidatum and / or Rumex acetosa, by means of solvent selective extraction. Products obtained by this process present high level of purity; being therefore useful in the preparation of nutraceutical (pharmaceutical and / or food) compositions with antioxidant, anti-inflammatory, antiviral, cardioprotective, neuroprotective, chemoprotective activities, besides protecting against infections and ischemia, treating type 1 and 2 diabetes, reducing obesity and preventing aging. Useful phytomedicines for the same therapeutic activity and prepared from the roots and / or rhizomes of Rumex acetosa or from their fractions are also provided.
Owner:UNIAO BRASILEIRA DE EDUCACAO E ASSISTENCIA MANTENEDORA DA PUC RS

Trans-resveratrol polysaccharide, method of producing thereof, and composition comprising thereof

An object of the present invention is to provide a trans-resveratrol derivative that resists isomerization to the cis-form. This object can be achieved by a method for producing a trans-resveratrol polysaccharide, the method comprising the step of bringing a trans-resveratrol glucoside into contact with sugar in the presence of γ-cyclodextrin glucanotransferase.
Owner:FAITH CO LTD

Process for synthesizing trimethoxyphenyl stilbene

The invention discloses a process for synthesizing trimethoxyphenyl stilbene, which includes subjecting 3, 5-dimethoxybenzyl alcohol to chloro by triphosgene to obtain 3,5-dimethoxybenzyl chloride in a high selectivity mode, then subjecting the 3,5-dimethoxybenzyl chloride and trimethyl phosphate to reaction to obtain phosphonate, then subjecting the phosphonate and anisic aldehyde to condensation under the action of sodium methoxide to obtain 3, 4', 5- trimethoxyphenyl stilbene. The yield of crude products can reach around 95%, and the yield of synthetical pure products is above 90%. According to the process for synthesizing the trimethoxy phenyl stilbene, all materials can be fully used, and the discharging of three wastes is low; the process for synthesizing the trimethoxy phenyl stilbene is environment-friendly in producing process and has the advantages of high conversion ratio, high selectivity, easiness in obtaining raw materials and recycling auxiliary raw materials, little in three waste pollution and suitable for industrial production. The 3, 4', 5- trimethoxy phenyl stilbene can be used as a key intermediate for synthesizing trans-resveratrol.
Owner:浙江新赛科药业有限公司

Method for separating trans-resveratrol from giant knotweed

InactiveCN102924239AAchieving Selectively Permeable SeparationLess quantitySemi-permeable membranesOrganic chemistryAlcoholAcetonitrile
The invention relates to a method for separating trans-resveratrol from giant knotweed. The method comprises the following steps of: (1) crushing the giant knotweed, adding methanol or 80 to 95 volume percent ethanol in an amount which is 20 to 50 times the massic volume of the giant knotweed, extracting, purifying by using macroporous resin, concentrating under reduced pressure, and drying to obtain an alcohol extract of the giant knotweed; (2) dissolving the alcohol extract of the giant knotweed into water, methanol or acetonitrile to ensure that the concentration of the alcohol extract of the giant knotweed in the obtained solution is 10 to 1,000mu g / ml to obtain a sample solution; and (3) pumping the sample solution and an extracting agent into a membrane separator, ensuring that the sample solution flows at the rate of 0.3 to 1.0ml / min in a membrane tube and the extracting agent contraflows at the rate of 0.3 to 1.0ml / min outside the membrane tube, adding a pH regulator into the extracting agent outside the membrane tube (the volume ratio of the pH regulator to the extracting agent is 0.1:99.9-1:99) after two phases inside and outside the membrane tube are balanced, collecting an extracting solution which flows outside the membrane tube, and concentrating under reduced pressure to obtain the trans-resveratrol. The method is high in selectivity and separation efficiency.
Owner:SOUTHERN MEDICAL UNIVERSITY

Topical Treatment Formulation of Natural Ingredients for Enhancing Sexual Response

The present invention relates to a topical composition to enhance sexual response. The composition includes L-arginine, trans-resveratrol, and a topical carrier wherein L-arginine is present in an amount not greater than about 10% and trans-resveratrol is present in an amount not greater than about 10% based upon the weight of the total composition. The invention also relates to a method of enhancing sexual response by topically applying the topical composition to the genitalia of a human, and an integrated product including the topical composition, a container for instantaneous delivery, and instructions for use.
Owner:AMATO TERI

Extraction method of resveratrol

The invention provides a preparation method of resveratrol, which relates to the field of medicament preparation and solves the problems of low preparation conversion rate, low yield and poor product quality of resveratrol in the prior art. The process comprises the following steps: pretreating giant knotweed used as raw material, washing away dust of the giant knotweed, cutting the giant knotweed into slices or preparing the giant knotweed into coarse powder, adding ethanol and heating to carry out reflux extraction, decompressing and distilling extract liquid to recover the ethanol, concentrating the ethanol into stiff paste, diluting the stiff paste by water for 10 times, adding enzymolysis liquid to carry out enzymolysis, heating and filtering the enzymatic enzymolysis liquid, decoloring the enzymolysis liquid by activated carbon, repeatedly recrystallizing the enzymolysis liquid by alcohol, and finally decompressing and drying the enzymolysis liquid to obtain a white resveratrol solid with purity of more than 98 percent. The extraction method of resveratrol greatly improves the production efficiency and the conversion rate, promotes active substances in the raw material to be converted into trans-resveratrol more, and further improves the quality of products with high purity, thereby being suitable for industrial production.
Owner:张守力

In vitro resveratrol-rich callus tissues derived from vitis thunbergii Sieb.et Zucc and method for producing the same

The present invention provides an in vitro resveratrol-rich callus tissue of Vitis thunbergii Sieb. et Zucc. which is a callus tissue developed from a tissue culture system containing one or more plant growth regulators (PGRs) and cultured from a stem or a petiole tissue explant of a wild type of V. thunbergii or a cultivated plantlet of V. thunbergii. The cultivated plantlet is in turn derived from a shoot of the wild type of V. thunbergii cultivated in a plantlet culture system containing no PGRs. The in vitro resveratrol-rich callus tissue of V. thunbergii is characterized by its containing at least about 1,000 to 10,000 mg / kg of dried weight of resveratrol, predominantly in the form of trans-resveratrol and / or resveratrol-O-glucoside, and being ready for harvest or subculture in about 30 days. The present invention further provides a method for cultivating the in vitro resveratrol-rich callus tissue, a method for extracting the resveratrol from the in vitro resveratrol-rich callus tissue, and a method for determining the resveratrol amount in the in vitro resveratrol-rich callus tissue by HPLC.
Owner:TATUNG UNIVERSITY +1

Total synthesis method of trans-resveratrol

The invention discloses a total synthesis method of trans-resveratrol. The total synthesis method comprises the following steps: (1) enabling 3,5-dihydroxy-benzoic acid to react with dimethyl sulfate, so as to generate 3,5-dimethoxy methyl benzoate; (2) enabling the 3,5-dimethoxy methyl benzoate to react with a reducing agent, so as to prepare 3,5-dimethoxybenzhydrol; (3) carrying out nucleophilic substitution on the 3,5-dimethoxy methyl benzoate and phosphorus tribromide, so as to generate 3,5-dimethoxy benzol benzyl bromide; (4) enabling the 3,5-dimethoxy benzol benzyl bromide to react through witting-horner, so as to prepare 3,5,4-triethoxy toluylene; and (5) preparing the trans-resveratrol from the 3,5,4-triethoxy toluylene. The total synthesis method has the advantages of being wide in material source, mild in reaction condition, friendly to environment, high in product yield, high in purity, applicable to industrialized mass production and the like.
Owner:HUNAN KEYUAN BIO PRODS

Method for preparing resveratrol

The invention discloses a method for preparing resveratrol, which comprises the following steps of: (1) preparing an intermediate (E)-2-(4-methoxyphenyl)-3-(3,5-dimethoxyphenyl)-acrylic acid; (2) performing decarboxylation reaction on the intermediate to prepare Z-3,4',5-trimethoxystilbene; and (3) performing protecting group removal or isomerization on the Z-3,4',5-trimethoxystilbene to prepare E-3,4',5-trihydroxystilbene, namely trans-resveratrol. In the method for preparing the resveratrol, inorganic alkali or organic alkali is added into an organic solvent and copper salt with catalytic amount is taken as a catalyst in the step (2), so compared with a quinoline / Cu powder catalyst in the prior art, the copper salt catalyst ensures that reaction time is greatly shortened, the reaction temperature is obviously reduced and reactants are difficult to carbonize; and the obtained product is single and easy to separate and purify.
Owner:SUZHOU UNIV

New antivirus, antibacterial method for animal and plant and product thereof

The invention provides the new method for antibiosis and anti-virus of animals and plants and the products thereof. Materials which contain trans-resveratrol or ramification thereof are used for replacing antibiotics to ensure that animals, plants and metabolite thereof become organic food.
Owner:宋彦彦 +2

Preparation method of dendrobium polysaccharides and dendrobine ethosomes and cosmetic

The invention discloses a cosmetic which comprises the following components in percentage by weight: 20-35% of dendrobium polysaccharides, 10-15% of glycerinum, 0-2 of ceramide, 42-65% of ultrapure water, 0.3-1% of dendrobine ethosomes, 0-2% of natural vitamin E, 0-1% of trans-resveratrol, 0-1% of vitamin C palmitate, 0-1% of alpha-arbutin and 0.1-1% of plant essential oil. The invention further provides a preparation method of the dendrobium polysaccharides and the dendrobine ethosomes in the cosmetic. The invention solves the technical problem of 'providing a cosmetic with dendrobium extracts (the dendrobium polysaccharides and the dendrobine ethosomes)', and the cosmetic disclosed by the invention has effects of ultraviolet resistance and oxidation resistance, meanwhile has effects of whitening skin and lightening stain, and moreover is purely natural and free of irritation.
Owner:宁波百岚德加进出口有限公司

Method for synthesizing trans-resveratrol by combining hydroxyl groups and protective groups

The invention relates to a method for synthesizing trans-resveratrol by combining hydroxyl groups and protective groups. The method is characterized in that in the process of synthesizing the trans-resveratrol, the hydroxyl group at a 4' site in the molecular structure is protected by adopting a benzyl group, and hydroxyl groups at 3' and 5' sites in the molecular structure are protected by adopting methyl groups. By adopting the method for synthesizing the trans-resveratrol by combining the hydroxyl groups and the protective groups, the purposes of low cost and easy obtaining of raw materials, easy crystallization and separation of an intermediate product and moderate reaction condition of protective group removal can be achieved. The method has the characteristics of high reaction yield, low cost, simpleness of industrial operation, and the like and is suitable for industrial production.
Owner:HUBEI UNIV FOR NATITIES

Nutraceutical Treatments for Diabetic and Non-Diabetic Wound Healing

In an embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, trans-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to reduce inflammation in mammals suffering from diabetes. In another embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, fr-απs-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to enhance wound healing in mammals suffering from diabetes. In an alternative embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, trans-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to reduce inflammation in mammals not suffering from diabetes. In another embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, trans-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera, combined synergistically to enhance wound healing in mammals not suffering from diabetes.
Owner:INTERHEALTH NUTRACEUTICALS

Tincture For Infusing Flavonoids And Methods Of Use

Methods and formulations for infusing bioavailable flavonoid tinctures into food, beverage, cosmetic or drug products with minimal or no effect on the alcohol by volume of the product is provided. A flavonoid tincture includes an amount of trans-resveratrol, pterostilbene, quercetin, or combinations thereof, mixed with a solvent of pure, or majority by weight, ethanol or Dimethyl sulfoxide The tincture is added to various food and beverages to make a bioavailable amount of flavonoids to be absorbed and metabolized by the body providing demonstrated health benefits.
Owner:HEART HEALTHY SPIRITS

Trans-resveratrol polysaccharide, method for producing the same, and composition comprising the same

An object of the present invention is to provide a trans-resveratrol derivative that resists isomerization to the cis-form. Another object of the present invention is to provide a trans-resveratrol derivative that has no toxicity against cells and has sufficient antioxidative properties and / or a sufficient whitening effect. This object can be achieved by a method for producing a trans-resveratrol polysaccharide, the method comprising the step of bringing a trans-resveratrol glucoside into contact with sugar in the presence of γ-cyclodextrin glucanotransferase.
Owner:FAITH CO LTD

Supplement composition for supporting DNA repair and method of use

Disclosed is a supplement composition for enhancing DNA repair process, comprising effective amounts of a carotenoid compound; a nicotinamide compound; a zinc compound; inositol hexaphosphate; water extract of uncaria tomentosa; trans-resveratrol; extract of arabidosis thaliana; extract of cauliflower; and extract of artemisia plants.
Owner:LIFE SCI INT
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