The invention relates to the technical field of immunological detection, specifically relates to a kit for quantitatively detecting anti-SS-A antibody IgG by utilizing magnetic particle chemiluminescence, a preparation method and a detection method thereof. The kit for quantitatively detecting anti-SS-A antibody IgG by utilizing magnetic particle chemiluminescence comprises an Anti-SS-A IgG calibration product, an Anti-SS-A IgG reagent 1#, an Anti-SS-A IgG reagent 2#, an Anti-SS-A IgG magnetic separation reagent, an Anti-SS-A IgG quality control material and a cleaning fluid. The invention also discloses the preparation method and the detection method for the kit. According to the detection method, on the basis of the traditional film strip immunization and enzyme linked immunosorbent assay, the sensitivity and the linearity range are increased by 3-5 orders of magnitudes and the quantitative detection is realized; the kit has the advantages of high sensitiveness, strong specificity, high accuracy, low cost, convenience in operation and objective judging result; the full-automatic chemiluminiscence immune analyzer is used for realizing the full-automatic use and has wide application prospect.