The invention provides a deodorizing and sterilizing insole and a manufacturing method thereof, belongs to the technical field of daily supplies and solves the problems of short service life and poorhealthcare effects of an existing insole. According to the manufacturing method of the deodorizing and sterilizing insole, raw materials including, in percent, 40%-50% of copper polyester fibers, 10%-20% of wood pulp fibers and 40%-50% of low melting point fibers are placed into a mixer and mixed into mixed fibers, the mixed fibers are placed into a fiber bale opener for bale opening, enter an opener for debonding, are sucked into a reserve box and treated into bobbin cotton, the bobbin cotton is placed into a carding machine, carded into a single-fiber state, placed into a lapping machine, uniformly folded and laid into needed width, a folded reticular fiber thin layer is repeatedly needled by seven needling machines, and fibers in the reticular fiber thin layer are drawn close and compressed, then enter a hot mill with the high temperature of 250 DEG C and are formed. The deodorizing and sterilizing insole has the advantages of low cost, simplicity in manufacture, strong deformationresistance and long service life.