I have discovered that trace metals such as 
copper, 
zinc, iron, and 
manganese that are necessary for the proper functioning of 
superoxide dismutase (SOD) and other deactivators of active-
oxygen molecules (which cause aging of 
skin and other 
skin disorders), can be delivered from the topical compositions. This is achieved by the preparation of 
copper and other 
trace metal complexes with phosphorylated nucleosides, such as nucleotides, and phosphorylated monosaccharides, such as phosphorylated glycosides which act as small molecular weight (SMW) 
transporter molecules. These 
trace metal complexes of nucleotides and glycosides can be prepared by an in-situ method in water, water-miscible 
organic solvent, or a mixture of water and water-miscible 
organic solvent from commonly available ingredients in concentrations that are desirable and can be accurately controlled. I have additionally discovered compositions to achieve the transport of 
copper from the surface 
layers of 
skin into the deeper 
layers of skin utilizing SMW 
transporter molecules; and the intra-cellular storage of copper ions in the 
cell, for example in a bound form with 
glutathione; and the intra-cellular transport of copper from 
glutathione to SOD apoprotein by metallochaperones; and the supply of energetic molecules, such as ATP, ADP, or phosphorylated saccharides for SOD metallochaperones to perform their intra-cellular 
metal transfer function. These cosmetic or pharmaceutical compositions are useful for antiaging and antiviral benefits.