The invention relates to the technical field of goaf grouting, in particular to a goaf grouting process method based on negative pressure drainage, which comprises the following steps: S1, according to a grouting and filling sequence, constructing N central
drill holes in a to-be-filled area, and respectively constructing M circumferential
drill holes around each central
drill hole at proper intervals; s2, after construction of all the drill holes is completed, hole opening grouting devices are installed at hole openings of the grouting holes; an orifice air extractor is mounted at the orifice of the negative-pressure air extraction hole; s3, after preparation is completed, a pumping and drainage test is started; s4, performing grouting operation; s5, at the last stage of grouting, when the orifice air extractor detects the grouting
slurry, the negative pressure pumping and drainage operation is ended; and when the grouting completion standard is reached, the grouting operation of the grouting drilling hole is completed. According to the method, multi-channel synchronous grouting can be achieved, the flowing and diffusing speed of
grout in the goaf is increased, the flowing speed of the
grout in the goaf is increased through negative pressure drainage while it is guaranteed that the
grout is diffused evenly and orderly, and the grouting and filling efficiency is improved.