The invention relates to a control device and a method of a CAST segmental inflow and synchronous denitrification and dephosphorization reinforcement process, which belongs to the technical field of SBR and variant process spent water biological denitrification. The denitrification and dephosphorization effect of the currently used CAST technique is not desirable. The device comprises a selector, a main reaction zone, an inlet pump, a stirrer, a diving stirrer, a return sludge pump, an aerator, an air compressor, a decant machine, a drain valve, a mud valve, a real-time controlling system and a sensor. The real-time controlling system is used for controlling a time-delay device which is connected with the inlet pump, the stirrer, the diving stirrer, the return sludge pump, the air compressor, the decant machine, the drain valve and the mud valve, a computer, and a data collecting card connected on the computer. By the processes of inflow anoxia stirring, inflow anaerobism stirring, aeration, sedimentation, drainage and leaving unused, the synchronous denitrification and dephosphorization is realized. The device and the method have the advantages of good denitrification and dephosphorization effect, low operation cost, and being capable of realizing intelligent control, and the like.